False Discovery Rates
False Discovery Rates
... of false discovery rates (Storey & Tibshirani ...incurring false positives, failing to identify truly differentially expressed genes is a major concern, leading to the false ...
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A direct approach to false discovery rates
... to false discovery rates is that the error rate is controlled for all values of m 0 (the number of true null hypotheses) simultaneously without us- ing any information in the data about m 0 ...
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Controlling false discovery rates in RNA-Sequencing data
... High throughput sequencing technologies are supplanting microarrays as the preferred technology for detecting and quantifying differential gene expression. The raw data produced by the a technique known as RNA-sequencing ...
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A Simulation Based Evaluation of the Bootstrap Bias Corrected Percentile Interval Estimators of the Local False Discovery Rates
... excessive false negative ...prevent false positive ...control false positive ...controlling false discovery ...lower false negative rates than Bonferoni correction and ...
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Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data
... affect false discovery rates as well as empirical p-values, which are an often-used alternative approach for identifying differen- tially expressed genes ...
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Outlier Detection and False Discovery Rates. for Whole-genome DNA Matching
... For many reasons, not all affected individuals share the same haplotype in a region bracketing a liability locus: i many individuals will have the disorder for other reasons, either gene[r] ...
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Controlling false discovery rates in factorial experiments with between subjects and within subjects tests
... of false positive test results has enjoined considerable attention in the statistical ...the False discov- ery Rate (FDR). This is the expected fraction of false positive results among all positive ...
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Power-enhanced multiple decision functions controlling family-wise error and false discovery rates
... of false discoveries for a pre-specified, usually small, overall size α, the optimal procedure dictates that not much size should be accorded those tests with either very low or very high ...
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Strong control, conservative point estimation and simultaneous conservative consistency of false discovery rates: a unified approach
... The false discovery rate (FDR) is a multiple hypothesis testing quantity that describes the expected proportion of false positive results among all rejected null ...
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Protein identification false discovery rates for very large proteomics data sets generated by tandem mass spectrometry
... We compared protein identification false discovery rate (FDR) estimates of MAYU , ProteinProphet and the naïve target-decoy strategy for four different data set sizes (1, 5, 10 and 20[r] ...
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False Discovery Rate Control with Groups
... It is hence desirable to incorporate such information when dealing with multiplicity problems to increase statistical power. In this article, we demonstrate the benefit of considering group structure by presenting a ...
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Private False Discovery Rate Control
... Our general approach is to adapt a well-known variant of the Benjamini-Hochberg procedure (BHq), making each step differentially private. This destroys the classical proof of FDR control. To prove FDR control of our ...
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False Discovery Control in Low-rank Estimation
... Approaches based on false discovery (rate) control have had substantial impact on how variable or feature selection is done in practice.. False discovery control techniques useful primar[r] ...
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On false discovery rate thresholding for classification under sparsity
... explicit rates of convergence of the excess risk to zero, as the number m of items to be classified tends to infinity and in a regime where the power of the Bayes rule is away from 0 and ...
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False Discovery and Its Control in Low Rank Estimation
... of false discoveries is the dimension of the remaining components of the estimated row/column ...or false discoveries, which is ill-suited to the smooth structure underlying low-rank ...
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Controlling the false discovery rate in multiple hypothesis testing
... and Hochberg, Y.,1995: Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing.. 1, 289-300.[r] ...
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Predicting Discovery Rates of Genomic Features
... *Department of Human Genetics and Génome Québec Innovation Centre, McGill University, Montréal, Quebec H3A 0G1, Canada and † NHLBI Exome Sequencing Project, National Heart Lung and Blood Institute, National Institutes of ...
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Challenges of the information age: the impact of false discovery on pathway identification
... representing special cases, the slope of the curve is 2466 articles per input node. Discussion These results demonstrate that pathways related to can- cer can be readily generated using sets of genes selected randomly ...
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On the false discovery proportion convergence under Gaussian equi-correlation
... a mean below π 0 α (because the false discovery rate of the BH procedure is below π 0 α for each m for PRDS statistics, see Theorem 1.2 in Benjamini and Yekutieli (2001)), the FDP can exceed π 0 α + ε (ε > ...
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FMR1, circadian genes and depression: suggestive associations or false discovery?
... depression collected for the DSPS sample result in stronger association. The DSPS and Sleep Clinic samples were recruited for differing comorbidities, with neither study focused primarily on depression. As a parametric ...
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