Fas/FasL
Protective Role of Fas-FasL Signaling in Lethal Infection with Herpes Simplex Virus Type 2 in Mice
... not Fas-mediated apoptosis, was involved ...of FasL- mediated apoptosis diminishes in a situation where a large amount of IFN- ␥ is rapidly induced by memory Th1 CD4 ⫹ T ...induce FasL-expressing ...
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Association between Fas/FasL gene polymorphism and musculoskeletal degenerative diseases: a meta analysis
... between FasL (rs5030772) and these two race groups of MSDD in any ...between FasL rs763110 and RA but it got an opposite ...in Fas (rs1800682) site, it has some errors in data extrac- tion of ...
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In vivo analysis of Fas/FasL interactions in HIV infected patients
... cause Fas/FasL interactions play a key role in peripheral T lymphocyte homeostasis, we investigated the susceptibility to Fas-mediated apoptosis in peripheral T lymphocytes and of FasL ...
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IFN γ and Fas/FasL are required for the antitumor and antiangiogenic effects of IL 12/pulse IL 2 therapy
... by Fas/FasL–mediated apopto- ...express FasL, treatment with IFN- γ and/or TNF- α enhances cell surface Fas expression and the susceptibility of Renca to Fas-mediated killing upon ...
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Huachansu suppresses human bladder cancer cell growth through the Fas/Fasl and TNF- alpha/TNFR1 pathway in vitro and in vivo
... to Fas by its physiological ligand, FasL, results in recruitment of adaptor molecules and activation of Caspase-8 or Caspase-10, to form death inducing signal- ing complex (DISC), transducing a downstream ...
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Original Article Expression of soluble Fas and soluble FasL in human nucleus pulposus cells
... of Fas and Fas ligand (FasL) in NP has been noted as the underlying mecha- nism of immune privilege of the ...kDa, FasL belongs to the tumor necrosis factor (TNF) ...receptor Fas, ...
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Role of the Fas/FasL Pathway in HIV or SIV Disease
... the Fas death pathway since activated T or B cells express ...in Fas and FasL expression in peripheral blood [50] as well as in thymus and other lym- phoid tissues ...express Fas [52] and ...
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Lymphocytic Expression of Fas and FasL Apoptotic Markers in Vitiligo
... disease. Fas receptor is a death receptor on the surface of cells that leads to programmed cell death (apoptosis) and FasL is its ...ligand. Fas/FasL system plays a crucial role in modulating ...
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Highly efficient, In-vivo Fas-mediated Apoptosis of B-cell Lymphoma by Hexameric CTLA4-FasL
... other bi-specific technologies, such as Signal Converter Proteins, are being assessed as well [20,22,36,37]. As we have shown in this study and previous ones, the main advantage of bi-specific biological drugs over ...
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Fas and FasL gene polymorphisms are not associated with cervical cancer but differ among Black and Mixed ancestry South Africans
... receptor Fas/CD95, which together with Fas ligand (FasL), triggers programmed cell death ...in Fas (FasR- 1377G/A, FasR-670A/G) and one in FasL (FasL844T/C) were studied in South ...
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FAS and FASL genetic polymorphisms impact on clinical outcome of malignant pleural mesothelioma
... reluctance against different treatment strategies. Thus, these new markers would help to distinguish the patients who would most likely benefit from these strategies and decrease the morbidities and mortalities ...
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Sheng Mai San protects H9C2 cells against hyperglycemia induced apoptosis
... investigated Fas and FasL ex- pression. The Fas/FasL signaling pathway can directly trigger cardiomyocyte apoptosis and has been reported in studies related to cardiovascular diseases ...[33]. ...
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Reactive oxygen species induced oxidative stress, neuronal apoptosis and alternative death pathways
... Reactive oxygen species (ROS) are produced as a by- product of cellular metabolic pathways and function as a critical second messenger in a variety of intra- cellular signaling pathways. The excessive intracellu- lar ...
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Original Article Distinct different sensitivity of Treg and Th17 cells to Fas-mediated apoptosis signaling in patients with acute coronary syndrome
... the Fas/Fas ligand ...rate, Fas/FasL expression and Caspase-3 activity of ...and Fas/FasL expression of Th17 cells among the four ...and Fas/Fas Ligand pathway ...
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Wentong decoction cures allergic bronchial asthma by regulating the apoptosis imbalance of EOS
... Background: Eosinophils (EOS) is one of the most important cells involved in the pathogenesis of chronic airway inflammation in asthma, and its apoptosis is part of the mechanisms of asthma. Therefore, this study aimed ...
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Association of FAS A-670G Polymorphism and Risk of Uterine Leiomyoma in a Southeast Iranian Population
... the FAS/Fas ligand (FAS/FasL) (CD95) pathway initiates ...apoptosis. FAS, also known as TNFRSF6/CD95/APO-1, is a member of the transmembrane receptor family and plays a significant role ...
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Tolerance induction ameliorates allograft vasculopathy in rat aortic transplants Influence of Fas mediated apoptosis
... of Fas expression and apoptosis in SMCs via a cGMP-independent mechanism ...of Fas or FasL in human monocytes and macrophages ...the Fas–FasL interaction is one of the critical modes ...
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Plasma concentrations of soluble Fas receptors (Fas) and Fas ligands (FasL) in relation to CD4+ cell counts in HIV 1 positive and negative patients in Yaounde, Cameroon
... While this study is strengthened by the inclusion of sam- ples from Cameroon, with high HIV diversity, some limita- tions need to be considered. The relatively small sample size may have lowered the power to identify ...
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Inhibition of TNFalpha in vivo prevents hyperoxia-mediated activation of caspase 3 in type II cells
... the Fas/FasL system [10], exposure to donors of nitric oxide or hydrogen peroxide [11], hyperoxia and nitric oxide [12], respiratory distress syndrome [13], and hyperoxia-mediated increase of total lung p53 ...
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Camptothecin induces the transit of FasL trimers to the cell surface in apoptotic HEp-2 cells
... Abstract: Fas ligand (L) is a membrane protein from the tumor necrosis factor (TNF) ...its Fas/CD95/APO1 receptor. Trimerization of FasL on the surface of effector cells is essential in the binding ...
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