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Fas receptor

Fas Receptor Modulates Lineage Commitment and Stemness of Mouse Neural Stem Cells

Fas Receptor Modulates Lineage Commitment and Stemness of Mouse Neural Stem Cells

... The Fas receptor, a member of the tumor necrosis factor (TNF) superfamily, has recently been shown to be important in NPC survival and immunoregulatory ...from Fas-deficient (lpr) mutant ...indicate ...

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CD74 interferes with the expression of fas receptor on the surface of lymphoma cells

CD74 interferes with the expression of fas receptor on the surface of lymphoma cells

... The Fas receptor is widely expressed by many tissues, yet the extent of Fas-mediated apoptosis does not correlate with the extent of Fas ...to Fas ligand (FasL)-induced apoptosis ...

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Fas receptor signaling inhibits glycogen synthase kinase 3β and induces cardiac hypertrophy following pressure overload

Fas receptor signaling inhibits glycogen synthase kinase 3β and induces cardiac hypertrophy following pressure overload

... results, Fas receptor acti- vation in cultured cardiomyocytes induced JNK1 activ- ity about threefold after 40 minutes (data not ...Because Fas signaling causes apoptosis in various cell types, we ...

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Activation of the Fas receptor on lung eosinophils leads to apoptosis and the resolution of eosinophilic inflammation of the airways

Activation of the Fas receptor on lung eosinophils leads to apoptosis and the resolution of eosinophilic inflammation of the airways

... controlling the resolution of eosinophilic inflammation are poorly understood. In the present study, we demonstrate that lung eosinophils obtained by bronchoalveolar lavage (BAL) after aerosol allergen provocation of ...

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MicroRNA-181c prevents apoptosis by targeting of FAS receptor in Ewing’s sarcoma cells

MicroRNA-181c prevents apoptosis by targeting of FAS receptor in Ewing’s sarcoma cells

... Japan). FAS expression plasmid (SC321759) was obtained from Ori- Gene ...for FAS (#8023), caspase 3 (#9662), cleaved caspase 3 (#9661), caspase 7 (#9492), cleaved caspase 7 (#9491), caspase 8 (#4790), ...

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Involvement of the CD95 (APO 1/Fas) receptor and ligand system in Helicobacter pylori induced gastric epithelial apoptosis

Involvement of the CD95 (APO 1/Fas) receptor and ligand system in Helicobacter pylori induced gastric epithelial apoptosis

... These data strongly support the important pathogenic and functional role of the CD95 receptor and ligand system in H. pylori–induced apoptosis. H. pylori induced simultaneous ex- pression of functional CD95L and ...

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T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions.

T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions.

... spleens of mice recovering from infection. DNA fragmentation associated with apoptotic cells in the spleens of infected mice was detected by in situ hybridization of a digoxigenin-labeled probe to the free 3 9 -OH ends ...

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Impaired growth and elevated Fas receptor expression in PIGA+ stem cells in primary paroxysmal nocturnal hemoglobinuria

Impaired growth and elevated Fas receptor expression in PIGA+ stem cells in primary paroxysmal nocturnal hemoglobinuria

... In the present study, PIGA-mutated CD59–CD34+ and nonmutated CD59+CD34+ cells in cytopheresis or bone marrow samples of PNH patients were purified by cell sorting and placed in a liquid [r] ...

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The Relative Role of Lymphocyte Granule Exocytosis versus Death Receptor-Mediated Cytotoxicity in Viral Pathophysiology

The Relative Role of Lymphocyte Granule Exocytosis versus Death Receptor-Mediated Cytotoxicity in Viral Pathophysiology

... the Fas receptor upon activation ...death receptor-induced apoptosis may lead to a higher virus production and contribute to the persistence and oncogenicity of FLIP-containing ...including ...

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Plasma concentrations of soluble Fas receptors (Fas) and Fas ligands (FasL) in relation to CD4+ cell counts in HIV 1 positive and negative patients in Yaounde, Cameroon

Plasma concentrations of soluble Fas receptors (Fas) and Fas ligands (FasL) in relation to CD4+ cell counts in HIV 1 positive and negative patients in Yaounde, Cameroon

... of Fas receptors and ligands in HIV-1 positive patients compared to HIV-negative ...in Fas receptor ex- pression in T-cells from HIV-1 infected children and adults ...membrane-bound Fas levels ...

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Lack of cell surface Fas/APO 1 expression in pulmonary adenocarcinomas

Lack of cell surface Fas/APO 1 expression in pulmonary adenocarcinomas

... The Fas receptor and ligand initiate an apoptotic ...ated Fas protein expression in 42 primary pulmonary ade- nocarcinomas, and Fas expression and function in the lung adenocarcinoma cell ...

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Neutrophil Suppresses Tumor Cell Proliferation via Fas /Fas Ligand Pathway Mediated Cell Cycle Arrested

Neutrophil Suppresses Tumor Cell Proliferation via Fas /Fas Ligand Pathway Mediated Cell Cycle Arrested

... the Fas ligand /Fas signal transduction leads to tumor cell cycle arrest with using Fas receptor antagonist and Fas knock out cell ...

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Species Difference in the Expression of Fas and Fas Ligand in Mature Mammalian Spermatozoa

Species Difference in the Expression of Fas and Fas Ligand in Mature Mammalian Spermatozoa

... Immunofluorescence microscopy. All the pro- cedures were conducted at room temperature unless otherwise specified. Indirect immunofluo- rescence staining for Fas and FasL was performed as described by Perticarari ...

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Essential roles of the Fas Fas ligand pathway in the development of pulmonary fibrosis

Essential roles of the Fas Fas ligand pathway in the development of pulmonary fibrosis

... Apoptosis may have a role in human diseases in 2 dif- ferent ways. First, diseases may be caused by a malfunc- tion of the apoptosis mechanism. Repair after an acute lung injury requires the elimination of proliferating ...

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Fast Lane to Python - Free Computer, Programming, Mathematics, Technical Books, Lecture Notes and Tutorials

Fast Lane to Python - Free Computer, Programming, Mathematics, Technical Books, Lecture Notes and Tutorials

... We will discuss this further in Section 1.15.6, but for now assume our source code consists of just a single .py file; in that case, Python does have global variables pretty much like in[r] ...

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Death versus survival: functional interaction between the apoptotic and stress inducible 
heat shock protein pathways

Death versus survival: functional interaction between the apoptotic and stress inducible heat shock protein pathways

... characterized by mitochondrial outer membrane permeabilization (MOMP), cytochrome c release, apoptosome assembly, and caspase activation. Hsps promote cell survival by preventing MOMP or apoptosome formation as well as ...

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Glucose induced β cell production of IL 1β contributes to glucotoxicity in human pancreatic islets

Glucose induced β cell production of IL 1β contributes to glucotoxicity in human pancreatic islets

... Islet isolation and culture. Islets were isolated from pan- creata of 11 organ donors at the Department of Surgery, University of Geneva Medical Center, as described (32–34). Islet purity was greater than 95% as judged ...

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The effects of leptomycin B on HPV infected cells

The effects of leptomycin B on HPV infected cells

... For the virus to survive and successfully replicate it has to interact with, manipulate, and disrupt numerous cellular components and processes. One of the biggest problems faced by the virus is the constant threat of ...

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Activation of the Fas/Fas ligand pathway in hypertensive renal disease in Dahl/Rapp rats

Activation of the Fas/Fas ligand pathway in hypertensive renal disease in Dahl/Rapp rats

... Recent evidence suggests that apoptosis is involved in sev- eral pathological processes in the lung [30–32] and kid- ney [33–37]. Using the Dahl/Rapp salt-sensitive (S) rat, which develops hypertensive nephrosclerosis ...

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Effect of high carbohydrate diet on elongase and desaturase activity and accompanying gene expression in rat’s liver

Effect of high carbohydrate diet on elongase and desaturase activity and accompanying gene expression in rat’s liver

... In this study, we have established that hepatic fatty acid elongases (Elovl-5 and Elovl-6) and desaturases (Δ5D, Δ6D, Scd-1, and Scd-2) are regulated by high carbohy- drate diet. Additionally, we have indicated that ...

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