fatty acid binding protein 1
Heart fatty acid binding protein and Aβ-associated Alzheimer’s neurodegeneration
... performed quantitative volume and surface-based ana- lysis of all baseline MRI scans using automated region-of-interest (ROI) labeling techniques [35,36], primarily focusing on the entorhinal cortex, a medial temporal ...
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Altered epidermal fatty acid-binding protein expression in hepatocellular carcinoma predicts unfavorable outcomes
... (ab84028, 1:1,000; Abcam, Cambridge, MA, USA) in a humid chamber at 4°C, washed three times with PBS, incubated for 1 hour with biotinylated goat anti-mouse antibody, and then stained with 3,3 ′ ...
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Phyletic distribution of fatty acid binding protein genes
... Figure 1. A Bayesian tree of FABPs. Bayesian probabilities more than 0.8 were shown at nodes. Tadh: Trichoplax adhaerens; Ctel: Capitella teleta; Hrob: Helobdella robusta; Lgig: Lottia gigantean; Smed: Schmidtea ...
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Fatty acid binding protein Role in esterification of absorbed long chain fatty acid in rat intestine
... oleate binding to FABP:flavaspidic acid-N-methyl-glucaminate and ...flavaspidic acid was reversible with higher oleate ...flavaspidic acid nor alpha-bromopalmitate inhibited acyl ...
11
Uptake of fatty acids by jejunal mucosal cells is mediated by a fatty acid binding membrane protein
... membrane fatty acid binding protein (MFABP) in brush border plasma membranes of the jejunum suggested that mucosal cell uptake of fatty acids might represent a carrier-mediated ...
11
The adipokine fatty-acid binding protein 4 and cardiac remodeling
... Of course, the concept of a possible dose-dependent association between FABP4 and the myocardium is completely speculative, and the majority of the publica- tions so far does not support a beneficial association of ...
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Exploring and Expanding the Fatty Acid Binding Protein superfamily in Fasciola species.
... The trematode liver flukes, Fasciola hepatica and F. gigantica, are the causative agents of fasciolosis, a foodborne zoonotic disease affecting grazing animals and humans worldwide. Liver fluke causes economic losses of ...
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A strategic approach for the visualisation of the low abundance protein fatty acid binding protein 7
... detect protein in a given sample; it uses gel electrophoresis to separate proteins according to their ...to protein visualisation is critical as they impact on the ability and reproducibility to detect ...
20
The orphan nuclear receptor small heterodimer partner is required for thiazolidinedione effects in leptin-deficient mice
... of fatty acid translo- case (CD36), fatty acid synthase (FAS), adipocyte fatty acid-binding protein (aP2), acetyl-CoA carboxylase 1 (ACC1) and stearoyl-CoA ...
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The human fatty acid-binding protein family: Evolutionary divergences and functions
... C/EBP binding site, and it was found that this mutation exhibited sig- nificantly reduced competitive-binding capacity (50 per cent) for C/EBPa compared with the wild-type (WT) FABP4 ...
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Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome
... intestinal fatty acid binding protein (I-FABP), a marker associated with enterocyte damage, were assayed using an ELISA (Hycult Biotechnology, Uden, the Netherlands) ac- cording to the ...
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Carbon tetrachloride affects inflammation-related biochemical networks in the mouse liver as identified by a customized cDNA microarray system
... Cells are activated and secrete inflammatory products in response to tissue damage. In addition to its metabolic functions, the liver is known to be involved in inflam- mation and immune responses [16]. Although ...
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Ulcerative colitis: functional analysis of the in-depth proteome
... Chemical compounds undergo phase I and phase II biotransformation reactions which make them more hydrophilic [46]. This allows their excretion with urine because the polar compounds are not reabsorbed in the kidneys ...
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Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells
... Metformin is a widely used anti-diabetic drug prescribed to more than 120 million people worldwide [4, 5]. In agreement with retrospective epidemiological studies, diabetic patients treated with metformin display a ...
10
Hepatitis C virus nonstructural protein 5A perturbs lipid metabolism by modulating AMPK/SREBP-1c signaling
... Mock group. Comparison of the NS5A group and each control group revealed significantly increased serum levels of ALT, FFAs and TG in NS5A-expressing mice (Fig. 1a, b). Furthermore, the histological alterations in liver ...
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Analysis of hepatic gene transcription in mice expressing insulin insensitive GSK3
... GSK3 (glycogen synthase kinase-3) regulation is proposed to play a key role in the hormonal control of many cellular processes. In- hibition of GSK3 in animal models of diabetes leads to normal- ization of blood glucose ...
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Fatty Acid Binding Protein in Small Intestine IDENTIFICATION, ISOLATION, AND EVIDENCE FOR ITS ROLE IN CELLULAR FATTY ACID TRANSPORT
... FABP was isolated from rat intestine by gel filtration and isoelectric focusing. It showed a reaction of complete immunochemical identity with proteins in the 12,000 mol wt fatty acid- binding ...
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Does the enterolactone (ENL) affect fatty acid transporters and lipid metabolism in liver?
... (ACBP) which provide high enough concentration gradi- ent for FA diffusion. An excessive intracellular FA flux into hepatocytes is esterified to triacylglycerols (TAG) and/or diacylglycerols (DAG) which may disturb ...
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Review: Omega-3 fatty acids transport through the placenta
... the fatty acid composition delivered to the fetus is largely determined by maternal circulating levels, the placenta preferentially transfers physiologically important long-chain polyunsaturated ...
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Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells
... Free fatty acids (FFAs) have also been shown to be involved in insulin resistance ...Palmitic acid (PA) was shown to promote mTOR signaling in rat hepatocytes [15] and also plays a key role in insulin ...
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