Fatty Acid Oxidation
Free fatty acid oxidation and carnitine levels in diphtheritic guinea pig myocardium
... Previous studies from this laboratory and by Wittels and Bressler have suggested that myocardial carnitine depletion and an accompanying decrease in fatty acid oxidation may contribute to the ...
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Modulation of Fatty Acid Oxidation and Glucose Uptake by Oxytocin in Adipocytes
... mitochondrial fatty acid oxidation, and FABP4, a fatty acid binding protein were both decreased by 100 and 150 nM OT after short-term incubation (Figure ...decrease fatty ...
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The effect of 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) on fatty acid oxidation in hepatocytes isolated from neonatal piglets
... increases fatty acid ...palmitic acid oxidation in hepatocytes isolated from suckled neonatal ...the fatty acid oxidation rate, the malonyl-CoA sensitive CPT acti- vity ...
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Complementation analysis of fatty acid oxidation disorders
... We assayed [9,10(n)-3H]palmitate oxidation by fibroblast monolayers from patients with fatty acid oxidation disorders. Activities in the different disorders were (percent control): short- ...
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Control of hepatic fatty acid oxidation in suckling rats
... non-esterified fatty acids can be mobilised in the absence of milk (Widdowson, 1981; Kuzawa, ...active fatty acid oxidation is also essential in the suckling period to sustain a high ...
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High-fat diet from perilla oil induces insulin resistance despite lower serum lipids and increases hepatic fatty acid oxidation in rats
... enhance fatty acid oxi- ...of fatty acid synthesis ...in fatty acid oxidation and a decrease protein expression of ...
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Non-invasive test using palmitate in patients with suspected fatty acid oxidation defects: disease-specific acylcarnitine patterns can help to establish the diagnosis
... With informative newborn-screening results, further confirmation is needed to specify defects of mitochondrial FAO. Specific enzyme assays are available for most fatty acid oxidation defects in order ...
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Effects of Clofibrate on Hepatic Fatty Acid Oxidation by Neonatal Pigs.
... hepatic fatty acid oxidation induced by clofibrate (a PPARα pharmaceutical agonist) in neonatal ...benefit fatty acid oxidation induced by the PPARα ...valeric acid (TC5), ...
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TET1 promotes fatty acid oxidation and inhibits NAFLD progression by hydroxymethylation of PPARα promoter
... In addition, after being fed with HFD, the mRNA levels of PPARα (peroxisome proliferators-activated receptor α), ACOX1 (Peroxisomal acyl-coenzyme A oxidase) and CPT1A (Carnitine Palmitoyltransferase 1A), which are key ...
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Child Neurology: Recurrent rhabdomyolysis due to a fatty acid oxidation disorder
... phosphatidic acid phosphatase deficiency, muscular dystrophies, congenital myopathies, and mitochondrial FAO defects must be considered in the differential diag- nosis of patients presenting with ...of ...
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Combined enzyme defect of mitochondrial fatty acid oxidation
... A young girl presented with recurrent episodes of muscle weakness culminating in a severe attack of generalized muscle weakness. In the muscle mitochondria from the patient there was an abnormal pattern of intermediates ...
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On the thermodynamics of fatty acid oxidation
... the oxidation of ...the oxidation of fatty acids (FAs) and triacylglycerols (TAGs), and provide some insight into the different values reported in the ...
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Control of polyunsaturated fatty acid oxidation
... Arachidonic acid 1 (175 mg) was dissolved in 5 ml of dichloromethane to make a stock solution (35 ...3-Tetradecylthiopropanoic acid 108 (10 mg, 0.03 mmol), arachidonic acid 1 (10 mg, ...phosphoric ...
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Stem cell metabolism in tissue development and aging
... Calorie restriction might also promote longevity in part by promoting the self-renewal of stem cells. Calorie restriction not only extends longevity but also prolongs the health of organisms, ranging from worms and flies ...
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Relationship between unusual hepatic acyl coenzyme A profiles and the pathogenesis of Reye syndrome
... reticulum. The results suggest that pathogenesis in Reye syndrome stems from generalized mitochondrial damage resulting in accumulation of acyl CoA esters. High levels of these compounds lead to inhibition of ...
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Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid–induced insulin resistance
... plasma fatty acid ...body fatty acid oxidation was measured at 9:30 pm on day 1 and 7 am on day 2 for 20 to 30 ...whole-body fatty acid oxidation was again measured ...
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Hormonal control of ketogenesis Rapid activation of hepatic ketogenic capacity in fed rats by anti insulin serum and glucagon
... long-chain fatty acid oxidation and ketogenesis that develops in the rat liver between 6 and 9 h after the onset of starvation was shown to be inducible much more rapidly by administration of ...
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REGULATORY ROLE OF L-ARGININE SUPPLEMENTATION ON SOME BIOCHEMICAL PARAMETERS IN HIGH FAT DIET-FED RATS
... High fat diet is a public health problem worldwide and considered as a risk factor for many diseases. This study aimed to investigate the effectiveness of L.arginine in high fat-fed rats. The present study indicate that ...
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Liver–Intestine CREBH Regulates Systemic Glucose and Lipid Metabolism
... CREBH and PPARα are crucial transcription factors in fatty acid oxidation and ketogenesis in the 125.. livers of energy-depleted mice.[r] ...
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<p>Lipid metabolism in chronic obstructive pulmonary disease</p>
... tricarboxylic acid (TCA) ...(ACC1). Fatty acid synthase (FAS) performs the condensation of acetyl-CoA and malonyl-CoA to produce the 16-carbon saturated fatty acid palmitate and other ...
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