Fe/sub 2/O/sub 3/:Li
In vitro and in vivo targeting imaging of pancreatic cancer using a Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoprobe modified with anti-mesothelin antibody
... Pancreatic cancer cell line SW1990 supplied by the Depart- ment of Digestive Diseases of Changhai Hospital (Shanghai, People’s Republic of China) was cultured. In order to test the targeting ability of the A-MFS with ...
13
Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... All animals were kept in stress-free, hygienic, and animal- friendly conditions (relative humidity 60% ± 10%, room tem- perature 20 ° C ± 2 ° C, and 12-hour light/dark cycle). Food and water were available ad ...
15
Biological responses to core–shell-structured Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>-NH<sub>2</sub> nanoparticles in rats by a nuclear magnetic resonance-based metabonomic strategy
... a 2-week acclimatization for Fe@Si NP intravenous adminis- tration: control group, low-dose 10 nm Fe@Si NP-exposure group (10L), low-dose 20 nm Fe@Si NP-exposure group (20L), high-dose 20 nm ...
16
Immobilized transferrin Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery
... DMP was suspended in 10 mL phosphate-buffered saline (PBS) solution, and incubated with 5 mg EDC and 5 mg NHS for 30 minutes at room temperature. Then, the products were separated using magnetic separation and ...
9
<p>Green Synthesis of Zeolite/Fe<sub>2</sub>O<sub>3</sub> Nanocomposites: Toxicity & Cell Proliferation Assays and Application as a Smart Iron Nanofertilizer</p>
... 37°C) before being seeded into the wells of 96-well plates at a concentration of 5000 cells/well. HDF and HMM cells were maintained using fi ltered (bottle-top vacuum fi lter systems, 0.22 μ m pore size; Corning Inc.) ...
16
Preparation, characterization, and cytotoxicity of CPT/Fe<sub>2</sub>O<sub>3</sub>-embedded PLGA ultrafine composite fibers: a synergistic approach to develop promising anticancer material
... CPT/Fe 2 O 3 -PLGA composite mats were successfully prepared by a simple, cost-effective electrospinning ...the Fe 2 O 3 -loaded PLGA composite fibrous mat and the ...
12
Vancomycin-modified Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@Ag microflowers as effective antimicrobial agents
... vancomycin-modified Fe 3 O 4 @ SiO 2 @Ag ...Van/Fe 3 O 4 @SiO 2 @Ag microflowers (Figure 3B and ...the Fe 3 O 4 @SiO 2 @Ag microflowers ...
18
Biocompatibility of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and their cytotoxic effect on MCF-7 cells
... of Fe 3 O 4 nano magnetofluid (0.5, 1.0, 1.5, and 2.0 g/L Fe 3 O 4 ), and a simple magnetic field irradiation group (a negative control group plus magnetic field ...CO 2 ...
10
Synthesis of composite magnetic nanoparticles Fe<sub>3</sub>O<sub>4</sub> with alendronate for osteoporosis treatment
... of Fe 3 O 4 , Dex/Fe 3 O 4 , and Bis/Dex/Fe 3 O 4 was verified by XRD (Figure ...standard Fe 3 O 4 pattern published by ...Dex/Fe ...
12
The effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> on immune function in normal ICR mice
... The levels of interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-10 (IL-10), and interferon- γ (INF- γ ) in serum were measured in duplicate using enzyme-linked immunosorbent assay kit according to the ...
7
In vitro toxicity of Fe<sub>m</sub>O<sub>n</sub>, Fe<sub>m</sub>O<sub>n</sub>-SiO<sub>2</sub> composite, and SiO<sub>2</sub>-Fe<sub>m</sub>O<sub>n</sub> core-shell magnetic nanoparticles
... uncoated, Fe m O n -SiO 2 composite flake-like, and SiO 2 -Fe m O n core-shell IONPs on cell viability, function, and mor- phology were tested 48 h postincubation in human ...
11
Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... strategy is to treat tumor cells with antioxidants, such as through the dietary administration of red wine and green tea polyphenols to prevent cancer. The other strategy is to provide pro-oxidant therapy, which consists ...
10
The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... cells/mL with RPMI-1640. The adjusted cells were placed in a 96-well microtiter plate in 200 µ L aliquots and cultured in the presence of T-lymphocytes mitogen (5 µ g/mL Con- canavalin A [ConA]) (Sigma Chemical Co, St. ...
6
Fe<sub>3</sub>O<sub>4</sub>-based PLGA nanoparticles as MR contrast agents for the detection of thrombosis
... Then, Fe 3 O 4 -PLGA or Fe 3 O 4 -PLGA-cRGD NPs at a final dosage of 1 mg lyophilized powder dissolving 1 mL phosphate- buffered saline (PBS) was administered to the rats by tail ...
14
Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... that Fe 3 O 4 -PLGA-PEG 2000 -doxorubicin has dose-dependent and time-dependent cytotoxicity against the A549 lung can- cer cell line (IC 50 ...that Fe 3 O 4 -PLGA-PEG 3000 ...
16
Fe<sub>3</sub>O<sub>4</sub>/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein
... composite Fe 3 O 4 /Au nanoparticles were synthesized by assembling gold nanoparticles on SH-modified Fe 3 O 4 and using them as nanocarriers for immobilization of HRP and a ...
11
The effects of magnetite (Fe<sub>3</sub>O<sub>4</sub>) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH<sub>3</sub>) cells and in RAW 264.7 macrophages
... to Fe 3 O 4 NPs (100 µ g/mL), there was a progressive decrease in the activity of MEP-induced channels, which occurred at the level of hyperpolarizing potentials ranging between − 80 and − 200 ...of ...
10
Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... Forty-two mice were randomly assigned to either the non- exercised control group (n = 6) or exercise groups (n = 36). Thirty-six mice were placed into plastic cylinders (23 cm tall × 14 cm diameter) containing water ...
8
Ultrasmall superparamagnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles: honey-based green and facile synthesis and in vitro viability assay
... the Fe 3 O 4 -NPs have spherical morphology and a uniform ...the Fe atoms as a covering material to create steric block, like the common stabilizers and ...
9
Preparation of Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles coated with gallic acid for drug delivery
... for 3 hours. To solubilize the formazan after 3 hours of incuba- tion, 100 µ L of dimethylsulfoxide was added to each well and kept in the dark at room temperature for 30 ...
12