Fe/sub 80/B/sub 12/Si/sub 8/
Enhanced pharmacological activity of Vitamin B<sub>12</sub> and Penicillin as nanoparticles
... Vitamin B 12 was measured using the electron paramagnetic resonance (EPR) ...Vitamin B 12 or nano Vitamin B 12 (H 2 O 2 + FeCl 2 + 4H 2 O + DMPO + DDW/Vitamin B 12 ...
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In vitro toxicity of Fe<sub>m</sub>O<sub>n</sub>, Fe<sub>m</sub>O<sub>n</sub>-SiO<sub>2</sub> composite, and SiO<sub>2</sub>-Fe<sub>m</sub>O<sub>n</sub> core-shell magnetic nanoparticles
... characterization, Fe m O n -SiO 2 composite flake-like and SiO 2 -Fe m O n core-shell IONPs demonstrated spherical shape with mean diameter of 98 ± 22 and 101 ± 19 nm, respectively (Figure ...2B–E). ...
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Effect of interaction of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and artesunate on apoptosis of K562 cells
... The following materials were purchased: 3-(4, 5- dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) (Ameresco, Solon, OH); Z-VAD-FMK (Beyotime Biotechnology); RPMI 1640 medium and fetal calf serum (GIBCO, USA); ...
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Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... average weights of the three TiO 2 NP groups and three Fe 3 O 4 - TiO 2 NP groups were 399.16 ± 13.56 g, 401.50 ± 16.48 g, 409.80 ± 26.60 g, 427.83 ± 23.16 g, 396.71 ± 27.86 g, and 413.80 ± 25.74 g, respectively. ...
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Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... of Fe 3 O 4 -magnetic nanoparticles (MNPs-Fe 3 O 4 ) on the expression of KCNQ 1 in cardiac muscle of mice at rest and at different times following a single bout of swimming ...at 12 hours post ...
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Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... for 12 days by releasing DNR and 5-Br-Tet from Fe 3 O 4 ...over 12 days, and nanoparticles were observed in the tumor tissue on histopathologic examina- tion after a single treatment with Fe 3 ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... Ferric chloride hexahydrate (FeCl 3 ⋅ 6H 2 O), ferrous chloride tetrahydrate (FeCl 2 ⋅ 4H 2 O), and ammonium hydroxide (25 wt%) were purchased from Fluka (Buchs, Switzerland). D, L-lactide and glycolide were purchased ...
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The effects of magnetite (Fe<sub>3</sub>O<sub>4</sub>) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH<sub>3</sub>) cells and in RAW 264.7 macrophages
... to Fe 3 O 4 NPs (100 µ g/mL), there was a progressive decrease in the activity of MEP-induced channels, which occurred at the level of hyperpolarizing potentials ranging between − 80 and − 200 ...of ...
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Fe<sub>3</sub>O<sub>4</sub>-based PLGA nanoparticles as MR contrast agents for the detection of thrombosis
... and 12 h light/dark cycle) and had free access to water and ...Then, Fe 3 O 4 -PLGA or Fe 3 O 4 -PLGA-cRGD NPs at a final dosage of 1 mg lyophilized powder dissolving 1 mL phosphate- buffered saline ...
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Preparation of Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles coated with gallic acid for drug delivery
... The in vitro bioassay, as shown in Figure 9, tells us that, after 72 hours of treatment, neither gallic acid nor FCG was toxic to a normal human fibroblast (3T3) cell line tested using various doses (0.47, 0.94, 1.88, ...
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Polyetherimide-grafted Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging
... from healthy Sprague Dawley rats was collected in heparin- coated tubes. The red blood cells (RBCs) were obtained by centrifugation at 1,500 rpm for 5 minutes, and the upper plasma was removed. The RBCs were then washed ...
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Immobilized transferrin Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery
... functional positions provided by PLGA for loading DOX onto DMP. Enhanced drug loading is due to the increased number of functional “arms” on the DMP surface. More functional arms could provide more functional positions ...
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The effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> on immune function in normal ICR mice
... Mice were randomly assigned to one of four groups (n = 10 per group). The doses of 5.14 mg/kg (low dose group), 20.7 mg/kg (medium dose group), and 51.4 mg/kg (high dose group) Fe 3 O 4 -MNPs, were dissolved in ...
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Biological responses to core–shell-structured Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>-NH<sub>2</sub> nanoparticles in rats by a nuclear magnetic resonance-based metabonomic strategy
... a 12/12-hour light/dark ...for Fe@Si NP intravenous adminis- tration: control group, low-dose 10 nm Fe@Si NP-exposure group (10L), low-dose 20 nm Fe@Si NP-exposure ...
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Pharmacokinetic parameters and tissue distribution of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles in mice
... time, the peak values were 119 ± 9 µ g/g and 211 ± 18 µ g/g, respectively, on day 3 after dosing. The value in the lung was 131 ± 15 µ g/g at six hours after dosing, and then decreased steadily. Levels in both kidneys ...
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The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... mg/kg Fe 3 O 4 - MNPs), medium-dose group (600 mg/kg Fe 3 O 4 -MNPs), and high-dose group (1200 mg/kg Fe 3 O 4 ...of Fe 3 O 4 - MNPs, and those in the control group were given RPMI-1640 (Gibco ...
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Synthesis of composite magnetic nanoparticles Fe<sub>3</sub>O<sub>4</sub> with alendronate for osteoporosis treatment
... of Fe 3 O 4 , Dex/Fe 3 O 4 , and Bis/Dex/Fe 3 O 4 was verified by XRD (Figure ...standard Fe 3 O 4 pattern published by ...Bis/Dex/ Fe 3 O 4 was smaller than that of Fe 3 O 4 ...
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Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... of Fe 3 O 4 (MgNPs-Fe 3 O 4 ) can enhance the delivery and efficacy of anticancer ...cells; 8-hydroxydeoxyguanosine levels were also elevated. MgNPs-Fe 3 O 4 alone reduced the viability of ...
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Vancomycin-modified Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@Ag microflowers as effective antimicrobial agents
... after 12-h cultivation. The control (absence of particles) and Fe 3 O 4 @SiO 2 microsphere-treated solutions did not inhibit the bacterial ...The Fe 3 O 4 @ SiO 2 –Ag seed showed higher antibacterial ...
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In vitro and in vivo targeting imaging of pancreatic cancer using a Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoprobe modified with anti-mesothelin antibody
... nanoprobe Fe 3 O 4 @SiO 2 modified with anti-mesothelin antibody (A-MFS) was prepared to target cells and tumor tissues highly expressing mesothelin in vitro (human pancreatic cancer cell line SW1990) and in vivo ...
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