Fibroblast growth factor 1 gene
The structure and function of vertebrate fibroblast growth factor receptor 1
... vertebrate fibroblast growth factor receptor (FGFR) gene family consists of four highly related genes, FGFR1, FGFR2, FGFR3 and FGFR4, encoding polypeptides that are 55% to 72% identical in ...
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Design and characteristics of cytotoxic fibroblast growth factor 1 conjugate for fibroblast growth factor receptor-targeted cancer therapy
... Total RNA from each cell line was extracted using the Univer- sal RNA Purification kit (EurX) and purified RNA was digested with DNase (Thermo Fisher Scientific) to remove any traces of genomic DNA contamination. RNA ...
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VEGF, FGF1, FGF2 and EGF gene polymorphisms and psoriatic arthritis
... endothelial growth factor (VEGF), epidermal growth fac- tor (EGF), and fibroblast growth factors 1 and 2 (FGF1 and FGF2) are powerful mitogens and play a central role in the ...
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Regulation of brachyury by fibroblast growth factor receptor 1 in lung cancer
... FGFR 1-4 and brachyury are showed in Figure ...FGFR gene expression ...brachyury gene expression was also observed in lung cancer cell lines (Figure ...
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Fibroblast Growth Factor Receptor 2 (FGFR2) Mutation Related Syndromic Craniosynostosis
... of 1 in 2,100-2,500 live ...The fibroblast growth factor receptor 2 (FGFR2) gene is perhaps the most extensively studied gene that is mutated in various craniosynostotic ...
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Spermatogonial Stem Cells: A Review of Essential Factor for Self-Renewal and Differentiation
... Fig. 1: A schematic representation of signaling model towards self-renewal and differentiation of ...Basic fibroblast growth factor; EGF: Epidermal growth factor; ETV5: Ets ...
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Fibroblast growth factor receptor 1 gene amplification is associated with poor survival in patients with resected esophageal squamous cell carcinoma
... A total of 526 Korean patients who underwent curative esophagectomy were analyzed. The clinical characteristics of the enrolled patients are presented in Table 1. There were 489 male and 37 female with a median ...
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Gene therapy using plasmid DNA encoding vascular endothelial growth factor 164 and fibroblast growth factor 2 genes for the treatment of horse tendinitis and desmitis: case reports
... Tendon or ligament injuries are one of the most common causes of orthopedic disorders in horses (Equus caballus) of any age and breed. Injuries of the digital flexor tendons (superficial and deep digital flexors) and the ...
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Molecular and clinical significance of fibroblast growth factor 2 (FGF2 /bFGF) in malignancies of solid and hematological cancers for personalized therapies
... FGFRs 1-3 can undergo alternative splicing during gene expression, and the IgIII domain is composed of an invariant IgIIIa exon alternatively spliced to IgIIIb or ...FGFRs 1-4 contains a ...
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Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2 induced catabolic activities in human articular chondrocytes
... Previously, we have shown that FGF-2 potently abro- gated BMP-7-mediated proteoglycan synthesis and accu- mulation [5,46]. Our current study demonstrates that administration of FGF-2 suppressed the FGFR3 gene via ...
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Mesenchymal stem cells induce endothelial cell quiescence and promote capillary formation
... of gene expression, extraction of RNA was performed with an ...target gene. Human Taqman W gene expression assays were angiopoietin-1 (ANG-1), angiopoietin-2 (ANG-2), α- smooth muscle ...
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THE ROLE OF GENE-GENE INTERACTIONS IN THE FORMATION OF THE GENITAL ENDOMETRIOSISIrina V. Ponomarenko, Vladimir F. Kulikovskiy, Evgeniy N. Krikun, Alexander A. Dolzhikov, Olga Yu. Bushueva and Alexey V. PolonikovDOWNLOAD/VIEW
... Fibroblast growth factor receptor 1 (FGFR1) encoded by this 174 gene is a member of the FGFR family, where amino acid sequence is highly conserved between members and throughout ...
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Analysis of differentially expressed genes among human hair follicle–derived iPSCs, induced hepatocyte-like cells, and primary hepatocytes
... and gene products identifying the charac- teristic biological properties of high-throughput genomic or transcriptome data, based on a rigorous biological back- ground and adopting a unified database of structural ...
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Carbon nanoparticles downregulate expression of basic fibroblast growth factor in the heart during embryogenesis
... downregulated gene and protein expression of the proangiogenic basic fibroblast growth factor, indicating that both diamond and graphite nanoparticles inhibit ...
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Coexpression of phosphotyrosine containing proteins, platelet derived growth factor B, and fibroblast growth factor 1 in situ in synovial tissues of patients with rheumatoid arthritis and Lewis rats with adjuvant or streptococcal cell wall arthritis
... expression of a 45-kD P-Tyr protein in the inflamed synovia. Treatment with physiological concentrations of dexamethasone suppressed both arthritis and P-Tyr expression in AA. P- Tyr was only transiently expressed in ...
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Expression and clinical significance of fibroblast growth factor 1 in gastric adenocarcinoma
... cells; 1, 10%–30% positive cells; 2, 30%–50% positive cells; 3, 50% positive ...staining, 1 for weak staining, 2 for moderate stain- ing, 3 for strong ...
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Fibroblast Growth Factor 23 and Left Ventricular Hypertrophy in Hemodialysis Patients
... risk factor for cardiovascular death in hemodialysis (HD) ...that fibroblast growth factor 23 (FGF23), which has an important role in phosphate metabolism, is elevated in HD ...
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Mesenchymal stem cells enhance ovarian cancer cell infiltration through IL6 secretion in an amniochorionic membrane based 3D model
... Fluorescence activated cell sorting (FACS) analysis Amniochorionic membrane was washed with PBS and red cells were removed with RBC lysis buffer (eBiosciences). We then chunked and digested the membrane in a pre- warmed ...
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Biologically active fibroblast growth factor 1 tagged with various epitopes
... had little or no effect on the growth factor's affinity for heparin and its mitogenic activity toward cells expressing FGFR1-IIIc. Apparently, FGF1, FGFR and heparin are able to form an active signaling complex on ...
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Use of anlotinib in intra-abdominal desmoplastic small round cell tumors: a case report and literature review
... On October 26, 2017, a 38-year-old man visited the Nanjing Jiangbei People’s Hospital presenting with anterior abdominal wall nodule for 1 month. Physical examination showed that the nodule had a hard texture, ...
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