fibroblast growth factor 21
Dietary moderately oxidized oil induces expression of fibroblast growth factor 21 in the liver of pigs
... FGF21: Fibroblast growth factor 21; GPI: Glucose-6-phosphate isomerase; L- CPT1: Liver isoform of carnitine palmitoyl transferase 1; OCTN2: Novel organic cation transporter 2; OF: Oxidized fat ...
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Serum fibroblast growth factor 21 levels are related to subclinical atherosclerosis in patients with type 2 diabetes
... Fibroblast growth factor 21 (FGF21) is a member of the endocrine FGF subfamily, which also includes FGF19 and FGF23 [1]. Unlike classical FGF molecules that act in an autocrine manner, these ...
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Fibroblast growth factor 21 inhibits atherosclerosis in apoE−/− mice by ameliorating Fas-mediated apoptosis
... FAS: Factor-associated suicide; FBS: Fetal bovine serum; FGF21: Fibroblast growth factor 21; HDL: High-density lipoprotein; HE staining: Hematoxylin and eosin staining; HUVECs: Human ...
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Original Article Elevated serum levels of fibroblast growth factor 21 from patients with nephrolithiasis
... serum fibroblast growth factor-21 (FGF-21) levels among patients with nephrolithiasis and healthy control, and to identify whether FGF-21 is ...
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Serum Fibroblast Growth Factor 21 as a Novel Biomarker in Prediction of Coronary Artery Disease Severity
... This study provides clinical evidence revealing that serum concentrations of FGF-21 are increased in CHD subjects with diabetes or hypertension in comparison to diabetic and hypertensive patients not suffering ...
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Deficiency of fibroblast growth factor 21 aggravates obesity-induced atrophic responses in skeletal muscle
... skeletal muscle inflammation and atrophy may be bene- ficial to protect from obesity-related metabolic disorders. Previous studies have shown that endogenous levels of FGF21 increase in genetically and/or diet-induced ...
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Additive relationship between serum fibroblast growth factor 21 level and coronary artery disease
... Methods: Two-hundred-and-fifty-three subjects visiting the Cardiology Department (Sixth People's Hospital affiliated to Shanghai JiaoTong University) were examined by coronary arteriography (to diagnose coronary artery ...
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Serum Fibroblast Growth Factor 21 and New Onset Metabolic Syndrome: KoGES ARIRANG Study
... Serum FGF21 levels were assessed with a sandwich enzyme- linked immunosorbent assay (ELISA) (FGF-21 ELISA Kit, Cat. No. AG-45B-5001-KI01; Adipogen, Switzerland) according to the manufacturer’s instructions. All of ...
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Significant gender difference in serum levels of fibroblast growth factor 21 in Danish children and adolescents
... Results: The girls had significantly higher levels of FGF21 compared with boys (155 pg/mL vs. 105 pg/mL, P = 0.04). 38 children (21%) had levels below detection limit of assay. Baseline levels of FGF21 showed ...
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Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21.
... stunts growth and development, including reducing total length, serum insulin-like growth factor 1 (IGF-1), and growth hormone signaling (Ables et ...2012). Fibroblast growth ...
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Dual effects of fibroblast growth factor 21 on hepatic energy metabolism
... approximately 21 o C and 40% humidity, and were allowed ad libitum access to water and standard laboratory chow comprising of 19% protein, 45% carbohydrate, 9% fat (Teklad 2019, Harlan, ...
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Fibroblast Growth Factor 21 Attenuates Vascular Calcification by Alleviating Endoplasmic Reticulum Stress Mediated Apoptosis in Rats
... Apoptosis is considered as a forerunner to vascular barrier destruction, which is a critical mechanism serving to VC[33]. During the procedure of VC, both apoptotic bodies induced by exposing to calcium and phosphate ...
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Photoperiodic regulation of FGF21 production in the Siberian hamster
... Thyroid hormone regulates hepatic expression of fibroblast growth factor 21 in a PPARalphadependent manner.. Adams AC, Kharitonenkov A 2012.[r] ...
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The role of glucagon on type 2 diabetes at a glance
... Unger and Cherrington [37] have proposed a “glucago- nocentric” vision of diabetes pathophysiology, and their arguments for defending this point of view include the following facts: glucagon augments the catabolic pro- ...
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Sleeve gastrectomy attenuates high fat diet-induced non-alcoholic fatty liver disease
... Fibroblast growth factor 21 (FGF21), a member of the fibroblast growth factor family, has emerged as a leading candidate in the regulation of energy homeostasis, ...
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Regulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted state
... Fibroblast growth factor (FGF) 15/19 and FGF21 are two atypical members of FGF19 subfamily that function as hor- ...Keywords: Fibroblast growth factor 15/19, Fibroblast ...
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Molecular and clinical significance of fibroblast growth factor 2 (FGF2 /bFGF) in malignancies of solid and hematological cancers for personalized therapies
... endothelial growth factor (VEGF) signaling, whereby FGF-induced signaling promotes resistance to VEGF receptor signaling for blocking of the VEGF ...
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Potent mitogenic effects of parathyroid hormone (PTH) on embryonic chick and rabbit chondrocytes Differential effects of age on growth, proteoglycan, and cyclic AMP responses of chondrocytes to PTH
... to 21-d-old chick chondrocytes or postnatal 21-d-old rabbit ...PTH: fibroblast growth factor, epidermal growth factor, and insulin stimulated chondrocyte proliferation ...
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Liver-derived human mesenchymal stem cells: a novel therapeutic source for liver diseases
... Similar to MSCs from other tissues, LHMSCs have the capacity for self-renewal, multipotent differentiation, and immunosuppression. LHMSCs exhibit high proliferative ability in long-term culture, and Wnt signaling has ...
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Therapeutic application of adipose-derived stromal vascular fraction in diabetic foot
... SVF: Stromal vascular fraction; FGF: Fibroblast growth factor; EGF: Epidermal growth factor; PGF: Platelet growth factor; VEGF: Vascular endothelial cell growth factor; G-CSF: Granulocyt[r] ...
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