Fibroblast Growth Factor(FGF):
Fibroblast growth factor signaling in ovarian cancer
... 11 1 Abstract Epithelial ovarian cancer is a rapidly progressive, highly lethal disease with low prevalence. It is responsible for 20% of all cancer-related deaths in the United States, since few patients are diagnosed ...
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Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2 induced catabolic activities in human articular chondrocytes
... 39. Martel-Pelletier J, Boileau C, Pelletier JP, Roughley PJ: Cartilage in normal and osteoarthritis conditions. Best Pract Res Clin Rheumatol 2008, 22:351-384. 40. Kaul G, Cucchiarini M, Arntzen D, Zurakowski D, Menger ...
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THE STERATEGIC ROLE OF FIBROBLAST GROWTH FACTOR-21IN OBESITY
... However, recently FGF21 is considered as a novel regulator of oxidative stress. The oxidative stress is associated with the metabolic disorders, including obesity; type 2 diabetes and insulin resis- tance (Cao & ...
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Fibroblast Growth Factor 23 (FGF23) and Disorders of Phosphate Metabolism
... Correspondence should be addressed to Seiji Fukumoto, [email protected] Received 28 May 2009; Accepted 27 July 2009 Recommended by Ali S Calikoglu Derangements in serum phosphate level result in ...
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Fibroblast growth factor signalling and regional specification of the pharyngeal ectoderm
... Institute of Biotechnology, Viikki Biocenter, University of Helsinki, Finland ABSTRACT Branchial arch development involves dynamic interactions between neural crest cells as well as ectodermal, endodermal and mesodermal ...
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The structure and function of vertebrate fibroblast growth factor receptor 1
... FGF, fibroblast growth factor; FGFR, fibroblast growth factor receptor; HSPG, heparan sulphate proteoglycan; Ig domain, immunoglobulin-like ...
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Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer
... 19. Yu K, Xu J, Liu Z, Sosic D, Shao J, Olson EN, et al. Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. ...
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Biologically active fibroblast growth factor 1 tagged with various epitopes
... * Corresponding author Abstract Background: Fibroblast growth factor (FGF) family members are involved in the regulation of a variety of biological phenomena. Because most of their activity is ...
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Lepidopteran Ortholog of Drosophila Breathless Is a Receptor for the Baculovirus Fibroblast Growth Factor
... The Bombyx mori nucleopolyhedrovirus (BmNPV) encodes a gene homologous to the mammalian fibroblast growth factor (FGF) family. We report the cloning of B. mori and Spodoptera frugiperda orthologous ...
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Design and characteristics of cytotoxic fibroblast growth factor 1 conjugate for fibroblast growth factor receptor-targeted cancer therapy
... only growth factor in the fibroblast growth factor family that binds with high affinity to all four FGFR types and is effectively internalized 13 and therefore is an excellent FGFR- ...
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Fibroblast growth factor receptor 4 (FGFR4) and fibroblast growth factor 19 (FGF19) autocrine enhance breast cancer cells survival
... cell growth, we identified fibroblast growth factor receptor 4 (FGFR4) as a potential mediator of cell ...secrete fibroblast growth factor 19 (FGF19), a canonical ligand ...
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Action of fibroblast growth factor 2 on the intervertebral disc
... Basic fibroblast growth factor stimu- lates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cdelta pathways in human adult ...
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Serum levels of vascular endothelial growth factor and basic fibroblast growth factor in children with brain tumors
... the growth and spread of malignancies, including brain ...endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), and by the release of their soluble forms ...
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Basic fibroblast growth factor as a growth inhibitor for cultured human tumor cells
... Basic fibroblast growth factor (bFGF) stimulates the proliferation of many cells and it is found in a wide variety of normal or transformed ...(autocrine) growth inhibitor for cultured Ewing's ...
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Fibroblast growth factor and its implications for developing and regenerating neurons
... Int J Dc, lliol 40 403 410 (1996) 403 I I I I I I I I I I I I I I I I I I I I I I Fibroblast growth factor and its implications for developing and regenerating neurons CLAUDIA GROTHE' and KONSTANTIN W[.] ...
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Effects of basic fibroblast growth factor on bone formation in vitro
... Basic fibroblast growth factor (bFGF) was studied for its effects on bone formation in cultured rat calvariae.. bFGF also increased the number of colcemid-induced metaphase arrested cell[r] ...
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Experimental analyses of the roles of the fibroblast growth factor family in skeletogenesis
... the growth of the brain and facial ...the Fibroblast Growth Factor Receptor 2 (FGFR2) gene was found in patients with Crouzon syndrome, one of the craniosynostoses and subsequently mutations ...
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Influence of Polycaprolactone and Basic Fibroblast Growth Factor on Gingival Fibroblasts
... basic fibroblast growth factor (bFGF) to promote gingival connective tissue growth while maintaining a barrier to the oral ...gingival fibroblast cell number and mesenchymal cell ...
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Astrocyte growth is regulated by neuropeptides through Tis 8 and basic fibroblast growth factor
... The important intracellular mechanisms of astrocyte growth are not well defined. Using an inhibitor of astrocyte proliferation, atrial natriuretic peptide (ANP), and the glial mitogen endothelin (ET-3), we sought ...
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Challenges and opportunities in the targeting of fibroblast growth factor receptors in breast cancer
... 23. Jackson D, Bresnick J, Rosewell I, Crafton T, Poulsom R, Stamp G, Dickson C: Fibroblast growth-factor receptor signaling has a role in lobuloalveolar development of the mammary-gland. J Cell Sci ...
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