Fibroblast Growth Factor 21-FGF21
Lower cerebrospinal fluid/plasma fibroblast growth factor 21 (FGF21) ratios and placental FGF21 production in gestational diabetes
... of FGF21 from human placental explants of women with GDM was significantly lower compared to control ...of FGF21 or secondly, that GDM placentae genuinely secrete less FGF21 than normal ...placental ...
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Potensi Terapeutik Fibroblast Growth Factor 21 terhadap Resistensi Insulin
... Abstrak Fibroblast growth factor 21 (FGF21) merupakan salah satu dari anggota FGF yang berperan sebagai faktor ...utama FGF21. Ekspresi FGF21 di hepar diatur oleh ...
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Significant gender difference in serum levels of fibroblast growth factor 21 in Danish children and adolescents
... Introduction: Fibroblast Growth Factor 21 (FGF21) is a novel metabolic factor with effect on glucose and lipid metabolism, and shown to be elevated in diseases related to ...
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Fibroblast growth factor (FGF21) protects mouse liver against D-galactose-induced oxidative stress and apoptosis via activating Nrf2 and PI3K/Akt pathways
... Fibroblast growth factor 21 (FGF21), as a member of the FGF family secreted predominantly by the liver, pancreas, and adipose tissues is identified as a critical regulator of long-term ...
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Hepatic SIRT1 Attenuates Hepatic Steatosis and Controls Energy Balance in Mice by Inducing Fibroblast Growth Factor 21
... revealed fibroblast growth factor 21 (FGF21), the hepatocyte-derived hormone, as the most markedly downregulated gene in liver-specific SIRT1 knockout (SIRT1 LKO) ...
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Regulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted state
... Abstract Fibroblast growth factor (FGF) 15/19 and FGF21 are two atypical members of FGF19 subfamily that function as hor- ...and FGF21 have pharmacological effects, and endogenous ...
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Additive relationship between serum fibroblast growth factor 21 level and coronary artery disease
... the fibroblast growth factor (FGF) 21 hormone-like protein are associated with development of several metabolic ...serum FGF21 level was also associated with the metabolic ...
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Fibroblast growth factor 21 prolongs lifespan and improves stress tolerance in the silkworm, Bombyx mori
... (23-27). FGF21 is a regulator that alleviates many age-related metabolic and stress ...which FGF21 induces lifespan extension, we detected the expression levels of BmAKT, BmAMPK, BmFoxO, BmTor1, and BmTor2 ...
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Serum Fibroblast Growth Factor 21 and New Onset Metabolic Syndrome: KoGES ARIRANG Study
... between FGF21 and the antidiabetic agent rosiglitazone, a PPAR-γ ago- nist, in stimulating glucose ...20 FGF21 signaling is medi- ated by the FGF receptor and the adapter molecule β-Klotho, whose expression ...
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Original Article Elevated serum levels of fibroblast growth factor 21 from patients with nephrolithiasis
... It has to admit that there exist restrictions of our study that required to be issued. First of all, the researched adopted a cross-sectional design to ensure the nephrolithiasis patients, so causality cannot be ...
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Serum Fibroblast Growth Factor 21 as a Novel Biomarker in Prediction of Coronary Artery Disease Severity
... There are some limitations in this study. The large number of the confounders in relation to the rather small sample size of patients enrolled in this study. A large sample size may be needed for more comprehensive ...
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Deficiency of fibroblast growth factor 21 aggravates obesity-induced atrophic responses in skeletal muscle
... of FGF21 induces an obesity-induced atrophic response in skeletal ...that FGF21 mRNA was ab- sent from the skeletal muscle of FGF21-deficient mice ...the FGF21-deficient mice given HFD were no ...
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Analysis of fibroblast growth factor-heparin interactions
... Tools and Resources 62 Figure 3.9 Purification of FGF-21. A.Bacteria from a 0.5 L culture were broken by sonication and loaded on a 3 mL column of Ni 2+ agarose. B. The 0.5 M imidazole eluate from this column was ...
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Fibroblast growth factor 19 entry into brain
... of growth factors, basic FGF (FGF2) is transported across the BBB by adsorptive transcytosis [13], whereas FGF21 crosses the BBB by simple diffusion without saturable influx ...
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Functional characterization of a Baculovirus fibroblast growth factor
... RESULTS Baculovirus fgfs vfgf is present in all baculoviruses sequenced to date that infect lepidopterans, but it is absent in the three baculoviruses that have been completely sequenced to date that infect other ...
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Fibroblast growth factor signaling in ovarian cancer
... conditioned growth medium (figure ...cell growth by FGF-2 (figure ...the growth suppression is due to inhibition of the same ...in growth inhibition of Dovitinib and of ...
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Serum level of fibroblast growth factor 21 in type 2 diabetic patients with and without metabolic syndrome
... FGF 21 is encoded by chromosome 19. Production of this factor takes place in the liver, white adipose tissue, skeletal muscle and ...on FGF21 (Iglesias et ...regulate FGF21 expression (Uebanso ...
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A Better Anti-Diabetic Recombinant Human Fibroblast Growth Factor 21 (rhfgf21) Modified with Polyethylene Glycol
... of fibroblast growth factor (FGF) family members, FGF21 has been extensively investigated for its potential as a drug candidate to combat metabolic ...human FGF21 (rhFGF21) was modified ...
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Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet
... Early growth response 1; ER, Endoplasmic reticulum; FA, Fatty acid; FGF, Fibroblast growth factor; FXR, Farnesoid X receptor; HBSS, Hank's buffered salt solution; H 2 O 2 , Hydrogen peroxide; ...
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Fibroblast growth factor receptor 4 (FGFR4) and fibroblast growth factor 19 (FGF19) autocrine enhance breast cancer cells survival
... To date, most of the understanding on the functional role of FGFRs and their signaling pathways has been derived mainly from the study of FGFR1-3. Only limited studies on FGFR4 have been reported so far. Although all ...
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