fibroblast-like cells
Regeneration of full-thickness skin defects by differentiated adipose-derived stem cells into fibroblast-like cells by fibroblast-conditioned medium
... F-CM contains a variety of factors known to be import- ant in healing skin wounds. Our study revealed that F- CM had factors promoting collagen synthesis in hADSCs as well as transdifferentiation of hADSCs into ...
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Osteoclast independent bone resorption by fibroblast like cells
... to excessive running in a running wheel by ICSS. As demonstrated previously [14], through positive reinforce- ment, ICSS results in running exercise that exceeds normal running activity of Wistar rats by up to 100-fold ...
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Original Article Directed differentiation of skin-derived precursors into fibroblast-like cells
... observe cells immunocytochemistry changes under fluorescence microscope, to validate the mRNA expression change of collagen I, collagen III, fibroblast-specific protein 1 (FSP-1) and alpha smooth muscle ...
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Characterization of fibroblast like cells from the rat olfactory bulb
... bulb fibroblast-like cells (OBFLCs) can be enriched only using adher- ence to culture plastic and by a rather simple ...isolated fibroblast-like cells from olfactory bulb with ...
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Influences of gamma interferon on synovial fibroblast like cells Ia induction and inhibition of collagen synthesis
... adherent cells cultured from rheumatoid synovial membranes are influenced by immune cells, and their ...synovial cells produce collagenase and prostaglandin E2 (PGE2), the levels of which are ...
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Canine Periodontal Stem Cells: Isolation, Differentiation Potential and Electronic Microscopic Characterization
... fibroblastic-like cells, single cell suspension of canine PDL cells was plated in 25-cm 2 culture flasks under specific culture ...PDL-derived cells to form adherent clonogenic cell clusters ...
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EXPERIMENTAL AUTORADIOGRAPHY AUTORADIOGRAPHICAL STUDY OF THE REGENERATION OF DAMAGED CORNEA STROMA
... the cells participating in regeneration of damaged corneal stroma by means of autoradiographic ...stroma cells the pulse and late 3 H-thymidine labeling method was ...stromal cells (pulse labeling) ...
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Fibroblast biology Signals targeting the synovial fibroblast in arthritis
... It has been claimed that the rheumatoid arthritis synovial fibroblasts differ from their nonrheumatoid counterparts in terms of growth rate, life span, glycolytic metabolism, syn- thesis of hyaluronan and sulfated ...
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Anti-DR5 mAb inhibits proliferation of human fibroblast-like synovial cells and reduces their cytokine secretion in vitro
... a comparison of the clinical characteristics of three groups of RA patients: 1) no growth of synovial fluid fibroblasts; 2) growth of DR5 + synovial fluid fibroblasts; and 3) growth of DR5 - synovial fluid fibroblasts. ...
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DREAM is reduced in synovial fibroblasts of patients with chronic arthritic pain: is it a suitable target for peripheral pain management?
... Qualitative results of reverse transcription-polymerase chain reactions (PCRs) using DREAM primer and DREAM nested primer. (a) DREAM amplicons of 409 base pairs (bp) in size in total RNA derived from cer- ebellum and ...
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Are mesenchymal stem cells in rheumatoid arthritis the good or bad guys?
... [16]. Cells of the interzone then give rise to the synovium, as well as other joint structures, including articular cartilage, me- nisci and ligaments ...endothelial cells are unlikely to descend from the ...
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The inhibitory activity of human interleukin 1 receptor antagonist is enhanced by type II interleukin 1 soluble receptor and hindered by type I interleukin 1 soluble receptor
... monocytes/macrophages. At the inflammatory site, IL-1 is a potent inducer of the production of prostaglandin E2 (PGE2) and metalloproteinases on fibroblast-like cells, thus triggering tissue damage. ...
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Protective effects of blue light-blocking shades on phototoxicity in human ocular surface cells
... cultured cells and NHDFs for pan keratin immuno- reactivity are shown in figure ...cultured cells but not in NHDFs, and fibroblast-like cells found in cultured cells were keratin ...
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Cross-talk between cancer cells and their neighbors via miRNA in extracellular vesicles: an emerging player in cancer metastasis
... tumor cells and fibroblasts is mediated by tumor-derived EVs that control lung metastasis of HCC, providing poten- tial targets for the prevention and treatment of cancer ...hand, fibroblast-derived EVs ...
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Bone morphogenetic protein 4 affects both trophoblast and non trophoblast lineage associated gene expression in human embryonic stem cells
... BG02 cells identified the formation and outgrowth of an im- mature vascular system when the cells are grown in a 3D Matrigel substrate in an endothelial cell growth medium ...the cells having the ...
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Expression of interleukin 18 receptor in fibroblast like synoviocytes
... FLS were exposed to IL-18 in a large number of experi- ments. We observed some ICAM-1 induction by IL-18 (∆ mean fluorescence intensity (MFI) ≥20%) in 5 of 33 FLS cultures (Fig. 4a), but unresponsiveness ( ∆ MFI < ...
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Donor age and long-term culture do not negatively influence the stem potential of limbal fibroblast-like stem cells
... stem cells which reside in the stem cell niche, where they are maintained in an undifferentiated ...stem cells have been located in the anterior stroma subadjacent to the basal side of the palisades of Vogt ...
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Autophagy induction contributes to the resistance to methotrexate treatment in rheumatoid arthritis fibroblast like synovial cells through high mobility group box chromosomal protein 1
... FLS: fibroblast- like synovial cells; HMGB1: high mobility group box chromosomal protein 1; LC3: microtubule-associated protein 1 light chain 3; LC3-II: microtubule- associated protein 1 light chain ...
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Fibroblast like synoviocyte metabolism in the pathogenesis of rheumatoid arthritis
... would like to further emphasize the unmet need to target FLS in combination with current and future therapies in rheumatoid arthritis ...synovial cells invaded and destroyed cartilage and bone in the joints ...
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NF κB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony stimulating factor
... In the presence of RANKL and M-CSF, DHMEQ inhibits differ- entiation of osteoclasts in cultures of mouse bone-marrow- derived monocyte/macrophage precursor cells by downregu- lation of NFATc1 [12]. We therefore ...
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