Fibronectin Binding Protein (Fba)
Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin binding adhesins fibronectin binding protein A and fibronectin binding protein B from Staphylococcus aureus
... doi:10.1111/j.1742-4658.2010.07835.x Fibronectin-binding proteins A and B are multifunctional LPXTG staphy- lococcal adhesins, comprising an N-terminal region that binds fibrinogen and elastin, and a ...
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Fibronectin Binding Protein Gene Recombination and Horizontal Transfer between Group A and G Streptococci
... 18. MacDonald, K. T., and A. C. Walker. 1989. Rheumatic heart disease in aboriginal children in the Northern Territory. Med. J. Aust. 150:503–505. 19. Molinari, G., S. R. Talay, P. Valentin-Weigand, M. Rohde, and G. S. ...
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Fibronectin binding protein B (FnBPB) from Staphylococcus aureus protects against the antimicrobial activity of histones
... by binding to the bacterial cell surface and causing membrane ...by binding to and sequestering histones away from the cell ...that fibronectin-binding protein B (FnBPB) is the main ...
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Staphylococcus aureus Fibronectin Binding Protein A Mediates Cell Cell Adhesion through Low Affinity Homophilic Bonds
... surface-located fibronectin-binding protein A (FnBPA) plays an important role in the accumulation phase of biofilm formation by methicillin-resistant ...Low-affinity binding by means of FnBPA ...
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Specific Identification of Listeria welshimeri and Listeria monocytogenes by PCR Assays Targeting a Gene Encoding a Fibronectin Binding Protein
... man fibronectin, a 450-kDa dimeric glycoprotein found in body fluids, on the surface of eukaryotic cells, and in an insoluble component of the extracellular ...The binding of fibro- nectin to ...with ...
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Evolution of sfbI Encoding Streptococcal Fibronectin Binding Protein I: Horizontal Genetic Transfer and Gene Mosaic Structure
... Streptococcal fibronectin-binding protein is an important virulence factor involved in colonization and invasion of epithelial cells and tissues by Streptococcus ...
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Fibronectin binding protein B variation in Staphylococcus aureus
... Ligand binding by recombinant FnBPB N23 isotypes was compared by ELISA-based solid phase assays and surface plasmon ...and fibronectin dose-dependently and saturably with similar ...affinities. ...
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Sequence diversity in the A domain of Staphylococcus aureus fibronectin binding protein A
... Conclusion We have identified seven isotypes of the N-terminal A domain of FnBPA in a collection of S. aureus strains repre- senting the genetic diversity of the species. Isotypes are on average 29.3% divergent in amino ...
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Evidence for steric regulation of fibrinogen binding to staphylococcus aureus fibronectin-binding protein A (FnBPA)
... FIGURE 5. The close proximity of Fn- and Fg-binding sites in S. aureus FnBPA suggests a mechanism for negative cooperativity. A, ternary complex. Putative structure of the ternary complex formed by Fg 䡠FnBPA䡠Fn. ...
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Surface displaced alfa-enolase of Lactobacillus plantarum is a fibronectin binding protein
... detect fibronectin binding, overlay assays were performed as described [28] with some modifica- tions: the PVDF membranes were incubated with blocking buffers I and II, washed with NN' buffer and overlaid ...
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The Borrelial Fibronectin-Binding Protein RevA Is an Early Antigen of Human Lyme Disease
... Infection Control, University Hospital of Frankfurt am Main, Frankfurt, Germany 3 Received 26 October 2009/Returned for modification 23 November 2009/Accepted 13 December 2009 Previous studies using small numbers of ...
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Human Immunoglobulin G Cannot Inhibit Fibrinogen Binding by the Genetically Diverse A Domain of Staphylococcus aureus Fibronectin-Binding Protein A
... FnBPA-fibrinogen binding with three alternative assays, to rule out that the coupling of either protein to xMAP beads could somehow affect correct antibody binding, for instance, due to conformational ...
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Production of fibronectin binding protein A at the surface of lactococcus lactis increases plasmid transfer In vitro and in vivo
... detect BLG production in protein extracts from isolated enter- ocytes confirming our hypothesis that the plasmid transfer occurs efficiently in enterocytes. Knowing that the isolated enterocytes are not 100% pure ...
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Pneumocystis carinii attachment to cultured lung cells by pneumocystis gp 120, a fibronectin binding protein
... J Clin Invest. 1991;88(2):403-407. https://doi.org/10.1172/JCI115318. Pneumocystis carinii is an extracellular organism which is thought to require attachment to alveolar epithelial cells for its growth and replication ...
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Evaluation of RevA, a Fibronectin-Binding Protein of Borrelia burgdorferi, as a Potential Vaccine Candidate for Lyme Disease
... surface protein during mammalian ...with fibronectin, RevA appears to be a good target for preventive ...RevA protein are cross-reactive among RevA proteins from diverse ...RevA protein to the ...
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Two distinct genotypes of prtF2, encoding a fibronectin binding protein, and evolution of the gene family in Streptococcus pyogenes
... In this study, we used software that utilized both the PFGE dendrogram and the prtF2 genotype status to infer the evolu- tion of the different genotypes by minimizing the total number of changes over the tree. The ...
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Subdomains N2N3 of Fibronectin Binding Protein A Mediate Staphylococcus aureus Biofilm Formation and Adherence to Fibrinogen Using Distinct Mechanisms
... surface-located fibronectin binding proteins A and B (FnBPA, FnBPB). Here we provide new insights into the requirements for FnBP-dependent biofilm formation by MRSA. We show that expression of FnBPs is ...
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Prevalence and distribution of adhesins and the expression of fibronectin binding protein (FnbA and FnbB) among Staphylococcus aureus isolates from Shahrekord Hospitals
... Discussion Staphylococcusaureus is an important hospital pathogen, the most common cause of surgical wound infections, the second leading cause of hospital pneumonia, and also responsible for 35% of hospital-acquired ...
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Gao, Jinliang (2009): Molecular characterization of the fibronectin-binding protein BBK32 of Borrelia burgdorferi sensu lato. Dissertation, LMU München: Medizinische Fakultät
... INTRODUCTION 3.3 Stage III (months through years after the initial infection) Lyme arthritis and acrodermatitis chronica atrophicans (ACA) are the most common manifestations of stage III (Fig. B-8). Lyme arthritis, which ...
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Role of the fibronectin-binding, collagen-binding, T-antigen region during nasopharyngeal infection by Streptococcus pyogenes
... the fibronectin-binding, collagen-binding, T-antigen (FCT) region, which notably encodes a pilus structure ...collagen-binding protein (cpa), and a fibronectin-binding ...
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