First-Line ART Failure
Predicting Virological Failure with Immunological Criteria in First Line ART Patients in a Resource Poor Setting
... initiated ART program in India on 1 st April 2004 ...second line ART program was started in January 2008 [2]. Patients on ART are followed for treatment failure with clinical, ...
10
Factors for nonadherence to first line art therapy in a cohort of Human Immunodeficiency Virus positive adult patients
... to first line ART and first line ART failure rate was only ...2.02%. First line ART is very effective and well tolerated and has a low failure ...
7
First-line antiretroviral treatment failure and associated factors in HIV patients at University of Gondar Teaching Hospital, Gondar, Northwest Ethiopia
... The objective of this study was to determine the preva- lence of first-line ART failure and to identify those risk fac- tors that contribute to treatment failure in the Ethiopian HIV ...
6
Retention in care and virological failure among adult HIV+ patients on second line ART in Rwanda: a national representative study
... second-line ART did not find a difference in efficacy between LPV/r or ATV/r plus two NRTIs and LPV/r with ...failing first line ART (2NRTI + 1NNRTI) and confirmed comparable potency ...
9
Schistosomiasis and HIV 1 viral load in HIV infected outpatients with immunological failure in Tanzania: a case control study
... used first line ART for more than 6 months and were identified to have immunological failure by the WHO criteria (50% drop from peak CD4 count, or CD4 count equal to or below baseline after 6 ...
7
Estimation of Clinical, Immunological and Virological Failure of First Line Antiretroviral Treatment in Kinshasa, Democratic Republic of Congo
... severe failure rate to first-line ART in Kinshasa was estimated at more than ...virological failure in first-line treatment in ...
8
Impact of second-line antiretroviral regimens on lipid profiles in an African setting: the DART trial sub-study
... 3,316 ART-naive adults with CD4 < 200 cells/mm 3 from Uganda and Zimbabwe initiated first-line ART with Combivir (co-formulated zidovudine + lamuvudine) plus tenofovir (n = 2469), abacavir ...
8
Evaluation of adverse effect of second line ART in PL HIV patients treated by second line ART
... India, ART at public sector hospital is provided free of charge under the National AIDs Control Organization ...second line ART regimens comprised of zidovudine (ZDV), lamivudine (3TC), tenofovir ...
8
Determinants of first line antiretroviral therapy treatment failure among adult patients on ART at central Ethiopia: un matched case control study
... immunologic failure. This brings management Table 3 ART treatment related condition of cases and controls of adult patient on antiretroviral therapy at ...
13
Incidence and predictors of second line antiretroviral treatment failure among adults living with HIV in Amhara region: a multi centered retrospective follow up study
... to ART will minimize the develop- ment of drug resistance to Antiretroviral (ARV) medica- tion, and it is key to suppress viral load, and decreasing the risk of mortality [7 – ...Despite, ART reduces HIV ...
9
Predictors of treatment failure, time to switch and reasons for switching to second line antiretroviral therapy in HIV infected children receiving first line anti-retroviral therapy at a Tertiary Care Hospital in Ethiopia
... treatment failure and frequent substitution of medications are a major setback to the economy ...second line ART drug increases by 24% as compared with the first line treatment [10, ...
9
Drug resistance in HIV patients with virological failure or slow virological response to antiretroviral therapy in Ethiopia
... initiating first-line ART. After eight years of large- scale ART introduction, this survey demonstrated a low rate of virological ...of ART in resource constrained ...
7
Involvement of the Genetic Diversity of HIV 1 in the Virological Treatment Failure of First Line Antiretroviral in Kinshasa
... drome; ART: Antiretroviral Treatment; ARV: Antiretroviral; CD4: Cluster for Differentiation T4; CHU-ULg: Centre Hospitalier Universitaire, Université de Liège; CRF: Circulating Recombinant Forms; d4T: Stavudine; ...
11
Immunologic and virologic failure after first-line NNRTI-based antiretroviral therapy in Thai HIV-infected children
... Methods: Antiretroviral (ART)-naïve HIV-infected children from 2 prospective cohorts treated with NNRTI-based HAART during 2001-2008 were included. CD4 counts were performed every 12 weeks and plasma HIV-RNA ...
6
A study of profile of patients failing first line NACO recommended ART
... In the present study authors found that 74.1% (40/54) patients who had FLA, had very low baseline CD4 count (<100 cells/mm3) at initiation of ART. These patients might have very high baseline viral load as ...
7
SESOTHO trial (“Switch Either near Suppression Or THOusand”) – switch to second line versus WHO guided standard of care for unsuppressed patients on first line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel group, open label, randomized clinical trial in Lesotho, Southern Africa
... In high-income settings with easy access to VL moni- toring, individualized patient management and a “ watch- and-wait ” strategy with monthly monitoring for patients with low-level viremia may be appropriate [5, 6]. ...
9
<p>Predictors of Clinical and Immunological Failure Among Patients on First-Line Antiretroviral Therapy (ART) in Southwest Ethiopia</p>
... conducted at St. Luke and Tulu bolo Hospital, 14 but it contrasts with the study conducted in Addis Ababa private facilities, which showed HIV patients who did not disclose their HIV status had a lower risk of treatment ...
10
Reasons for first line ART modification over the years during the ART scale up in Uganda
... the ART modifications were due to reasons other than treatment failure, consisting mainly in sin- gle drug substitution due to toxicity and contraindica- ...any ART substitution, since once a drug ...
8
Comparision and evaluation of the clinical features of the patients of ART 1 failure who have started ART 2 medication
... at ART plus Centre, Kanpur. All patients on 1st line ART treatment in the centre were screened for treatment failure as decided by SACEP from 2016 to ...Treatment failure was suspected ...
9
Viral load detection and management on first line ART in rural Rwanda
... The uptake of routine VL monitoring was very high after decentralization of a VL testing platform in a rural area of Rwanda. The vast majority (88.5%) of patients tested had a suppressed VL. Among patients with ...
9