first-line therapy
First-line therapy in atypical hemolytic uremic syndrome: consideration on infants with a poor prognosis
... effective therapy for infants with aHUS of rapidly progressive onset, when plasmapheresis is not feasible ...the first-line therapy for infants with hypocomplemente- mia accompanied by the ...
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Pemetrexed as first-line therapy for non-squamous non-small cell lung cancer
... 18. Shepherd FA, Dancey J, Arnold A, et al. Phase II study of pemetrexed disodium, a multitargeted antifolate, and cisplatin as first-line therapy in patients with advanced NSCLC: a study of the ...
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First-line therapy of chronic myeloid leukemia – focus on dasatinib
... Abstract: Dasatinib is a broad spectrum, ATP-competitive, tyrosine kinase inhibitor with low nM activity against Bcr-Abl, Src, and other tyrosine kinases. This activity has allowed dasatinib to emerge as one of the most ...
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Botulinum toxin A should not be first line therapy for overactivebladder
... failed first-line therapy, I would suggest that failing anticholinergic medication is likely a foregone ...the first-line treatment for OAB, rather than toiling on with ineffective ...
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The Use of Iodine as First Line Therapy in Graves' Disease Complicated with Neutropenia at First Presentation in a Paediatric Patient
... In cases where anti-thyroid thionamides are contraindicated due to the risk of side effects such as agranulocytosis or neutropenia, Lugol's iodine may be an alternative temporary form of first line ...
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Eculizumab as First-Line Therapy for Atypical Hemolytic Uremic Syndrome
... have important implications in the management of aHUS patients aged , 1 year. Because safe discontinuation of eculizumab is possible if the unique cause of TMA is identi fi ed as mutations in DGKE or a de fi ciency in ...
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First line therapy for post traumatic stress disorder : a systematic review of cognitive behavioural therapy and psychodynamic approaches
... The literature also supports alternative forms of TF- CBT, including eye movement desensitisation and reprocessing (EMDR) and cognitive processing therapy (CPT) as effective treatments for PTSD (Hofmann et al., ...
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Retroperitoneal solitary fibrous tumor: surgery as first line therapy
... Solitary fibrous tumors (SFT) are extremely rare spindle cell neoplasms with a varied presentation. First described as a pleural tumor by Klemperer et al. later they were identified in extra-thoracic sites, most ...
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Subsequent anti-VEGF therapy after first-line anti-EGFR therapy improved overall survival of patients with metastatic colorectal cancer
... OS after first-line therapy was affected by regimens of subsequent chemotherapy or targeted therapy. As for che- motherapy, irinotecan and oxaliplatin alone or coupled with FU and LV are ...
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Single Center Study of Prescribing and Treatment Outcomes of Patients with Chronic Myeloid Leukemia
... first-line therapy with IM after diagnosis were eligible for this study and only prior therapy with Hydroxyurea at initial of prognosis was ...
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Symptom burden & quality of life among patients receiving second line treatment of metastatic colorectal cancer
... second-line therapy, after patients had received prior treatment and experienced disease ...second-line therapy persist, and that symptoms assumed to reflect treatment group effects may be ...
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A randomized controlled phase II trial of vaccination with lysate loaded, mature dendritic cells integrated into standard radiochemotherapy of newly diagnosed glioblastoma (GlioVax): study protocol for a randomized controlled trial
... the first-line therapy for GBM combines maximal safe resection, fractionated radiother- apy with concomitant alkylating temozolomide (TMZ) chemotherapy followed by adjuvant ...
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Tyrosine kinase inhibitor combination therapy in first-line treatment of non-small-cell lung cancer: systematic review and network meta-analysis
... as first-line therapy, alone or in combination regimens, and reporting at least one outcome measure of interest (ie, PFS, OS, time to progression, response rate, safety or health-related quality of ...
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Case report of EUS-guided endoscopic transduodenal necrosectomy in a patient with sleeve gastrectomy
... initial therapy but endoscopic ultrasound (EUS) guided transmural drainage has been adopted as the first line therapy for symptomatic pseudocysts and walled off pancreatic necrosis (WOPN) ...
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... Although, QT is a highly effective regimen that could be recommended as a first-line therapy, bismuth is not available in many developed countries due to its potential nephrotoxicity [25-27]. ...
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Oral Versus Intravenous Rehydration of Moderately Dehydrated Children: A Randomized, Controlled Trial
... initiate therapy was substantially shorter in the ORT group (Table ...for therapy if the child should be- come dehydrated again and 72-hour ED-revisit ...
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Clinical impact of targeted therapies in patients with metastatic clear-cell renal cell carcinoma
... in line with other publications, our results suggest that targeted therapies are associated with improved overall survival in comparison with ...targeted therapy effectiveness in the clear-cell renal cell ...
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The cost-effectiveness of pegaspargase versus native asparaginase for first-line treatment of acute lymphoblastic leukaemia: a UK-based cost-utility analysis
... The generalisability of results from this model may be limited where treatment practices, healthcare systems and/or cost structures are significantly different from the UK. While mapping results to other countries should ...
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Stem cell transplantation of matched sibling donors compared with immunosuppressive therapy for acquired severe aplastic anaemia: a Cochrane systematic review.
... According to the 2009 Guidelines for the diagnosis and management of aplastic anaemia of the British Committee for Standards in Haematology, 4 fi rst-line allo- geneic haematopoietic stem cell transplantation ...
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Comparative effectiveness of early-line <em>nab</em>-paclitaxel vs. paclitaxel in patients with metastatic breast cancer: a US community-based real-world analysis
... ment line were included in the TTNT analysis, which may help in explaining the slightly longer TTNT observed here compared with the TTP in the Phase III ...
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