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fixed dose combination products

FORMULATION AND EVALUATION OF FIXED DOSE COMBINATION PRODUCTS OF ANTITUBERCULAR DRUG

FORMULATION AND EVALUATION OF FIXED DOSE COMBINATION PRODUCTS OF ANTITUBERCULAR DRUG

... Objective of the present study is to formulate and evaluate fixed dose combination tablets of Rifampicin and Isoniazid. The granules of Rifampicin and Isoniazid were prepared separately by wet ...

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A rapid stability indicating, fused core HPLC method for simultaneous determination of β artemether and lumefantrine in anti malarial fixed dose combination products

A rapid stability indicating, fused core HPLC method for simultaneous determination of β artemether and lumefantrine in anti malarial fixed dose combination products

... a combination of an artemisinin derivative with a co-drug such as lumefantrine, amodiaquine or mefloquine; most malaria endemic countries have now adopted artemisinin-based anti-malarial combination therapy ...

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Fixed dose combination products as Oro-dispersible tablets: A review

Fixed dose combination products as Oro-dispersible tablets: A review

... FDC products is the combination rule as described in FDA’s guidance for development of FDC and co- packaged drug products as well as in 21CFR ...FDC products for ...the combination is ...

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DEVELOPMENT  AND  VALIDATION  INDICATING RP-HPLC METHOD FOR T SELECTED COMBINATIONAL ANTIVIR PHARMACEUTICAL DOSSAGE FORMS

DEVELOPMENT AND VALIDATION INDICATING RP-HPLC METHOD FOR T SELECTED COMBINATIONAL ANTIVIR PHARMACEUTICAL DOSSAGE FORMS

... in combination with other antivirals for the treatment of chronic HCV ...into fixed dose products, the viral lifecycle can be targeted at multiple stages while simultaneously reducing the risk ...

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DEVELOPMENT OF ORALLY ADMINISTERED FIXED DOSE COMBINATION (FDC) PRODUCTS: PHARMACOKINETIC AND BIOPHARMACEUTICAL CONSIDERATIONS

DEVELOPMENT OF ORALLY ADMINISTERED FIXED DOSE COMBINATION (FDC) PRODUCTS: PHARMACOKINETIC AND BIOPHARMACEUTICAL CONSIDERATIONS

... ABSTRACT: Combination drug therapy has been shown to be beneficial in chronic multifactorial diseases, infectious diseases and in the treatment of comorbid ...inhibitors. Fixed dose combinations ...

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JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

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... irrational fixed dose combination antimicrobials can increase the antimicrobial ...of fixed dose combination of antimicrobials certain measures like developing guidelines for ...

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Formulation and Development of Fixed Dose Combination of Artemether and Lumefantrine Tablets for the Treatment of Malaria.

Formulation and Development of Fixed Dose Combination of Artemether and Lumefantrine Tablets for the Treatment of Malaria.

... India Fixed Dose Combination (FDC) of Drugs / medicines has drawn the attention of health service providers and the service ...A fixed dose combination (FDC) is a formulation of ...

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THE CRAVE OF  FIXED DOSE COMBINATION IN INDIAN MARKET

THE CRAVE OF FIXED DOSE COMBINATION IN INDIAN MARKET

... drug products introduced worldwide during the last decade were FDC ...new products were fixed ration combinations, whereas, in European countries like Spain, it was up to ...

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Capillary electrophoresis for the assay of fixed dose combination tablets of artesunate and amodiaquine

Capillary electrophoresis for the assay of fixed dose combination tablets of artesunate and amodiaquine

... hydrolysis products [5], from artelinic acid, a potential anti-malarial drug [6] and for AS determination in caco-2 cells ...in fixed-dose combined formulations has been investigated in this ...

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Quality of fixed dose artemether/lumefantrine products in Jimma Zone, Ethiopia

Quality of fixed dose artemether/lumefantrine products in Jimma Zone, Ethiopia

... Artemisinin-based combination therapy (ACT) has been recom- mended as a first-line treatment for uncomplicated Plasmodium falciparum malaria almost in all endemic ...of fixed dose combination ...

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Tramadol/paracetamol fixed-dose combination in the treatment of moderate to severe pain

Tramadol/paracetamol fixed-dose combination in the treatment of moderate to severe pain

... efficacy. Fixed-dose combination analgesics with two or more agents may offer additive or synergistic benefits to treat the multiple mechanisms of ...recent fixed-dose ...

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Design of Experiments for Coating Process of Valsartan and Pravastatin Fixed-dose Combination Tablet

Design of Experiments for Coating Process of Valsartan and Pravastatin Fixed-dose Combination Tablet

... As shown in Table 1, the initial risk assessments showed that assay and degradation products were at a high risk of being affected by the coating process as final process of the overall manufacturing process for ...

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 FIXED DOSE COMBINATION AND DISEASE MANAGEMENT

 FIXED DOSE COMBINATION AND DISEASE MANAGEMENT

... of combination product/ fixed dose combinations ...(FDCs). Combination products, also known as fixed dose drug combinations (FDCs) drug, are combinations of two or more ...

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Aclidinium bromide/formoterol fixed-dose combination therapy for COPD: the evidence to date

Aclidinium bromide/formoterol fixed-dose combination therapy for COPD: the evidence to date

... formoterol combination on isolated human bronchial ...the combination model indicated a synergistic action at the low doses of aclidinium and formoterol in inducing smooth muscle relaxation in ...

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Artesunate amodiaquine fixed dose combination for the treatment of Plasmodium falciparum malaria in India

Artesunate amodiaquine fixed dose combination for the treatment of Plasmodium falciparum malaria in India

... analysis and listing was done on safety population. The intent to treat (ITT) population comprised of all patients who were randomized, received at least one dose of study drug and underwent at least one efficacy ...

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Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO® (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers

Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO<sup>&reg;</sup> (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers

... A fixed-dose combination of naproxen and esomeprazole magnesium has comparable upper gastrointestinal tolerability to celecoxib in patients with osteoarthritis of the knee: results from two random- ...

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 THERAPEUTIC EFFICACY OF HYDROCHLOROTHIAZIDE WITH LOSARTAN AS A FIXED DOSE COMBINATION BY LC-MS/MS

 THERAPEUTIC EFFICACY OF HYDROCHLOROTHIAZIDE WITH LOSARTAN AS A FIXED DOSE COMBINATION BY LC-MS/MS

... The main rationale of this study is to estimate the pharmacokinetic parameters of FDC containing Losartan (50 mg each) and Hydrochlorothiazide (12.5 mg) where metabolite Losartan Carboxylic Acid (LCA) is formed in plasma ...

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1-s2.0-S0140673617322997-main.pdf

1-s2.0-S0140673617322997-main.pdf

... daily fixed-dose combinations of either bictegravir 50 mg, emtricitabine 200 mg, and tenofovir alafenamide 25 mg or dolutegravir 50 mg, abacavir 600 mg, and lamivudine 300 mg, with matching ...

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Safety and effectiveness of a fixed-dose combination of olmesartan, amlodipine, and hydrochlorothiazide in clinical practice

Safety and effectiveness of a fixed-dose combination of olmesartan, amlodipine, and hydrochlorothiazide in clinical practice

... the combination of oral antidiabetic drugs with antihypertensive medications may have a complementary effect on the tolerability profile of the two types of ...

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