Fixed-dose drug combinations
Assessment of utilization pattern of fixed dose drug combinations in primary, secondary and tertiary healthcare centers in Nepal: a cross-sectional study
... inappropriate drug use [5] such as the irrational fixed dose drug combinations (FDCs) that are readily available in the ...in fixed propor- tions in a single dosage form [6]. ...
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Assessment of the availability and rationality of unregistered fixed dose drug combinations in Nepal: a multicenter cross-sectional study
... Background: The medications that are registered and available in a country are meant for the prevention and treatment of ailments and diseases. However, a lack of effective regulatory bodies and operative control ...
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A STUDY OF PREVAILING SCENARIO OF FIXED-DOSE DRUG COMBINATIONS (FDCs) AVAILABLE IN INDIAN MARKET
... Similarly, combinations of NSAIDs and skeletal muscle relaxant may be considered .... Combinations of analgesics are considered as rational, only when active ingredients demonstrate synergistic analgesic ...
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Assessment of rational use of fixed dose combinations in hypertension in a tertiary care teaching hospital in north India
... Methods: It was a cross-sectional observational study conducted in the cardiology outpatient department of ASCOMS and H, Sidhra, Jammu, Jammu and Kashmir from February 2016 to July 2016. In the study 92 prescriptions of ...
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FORMULATION AND EVALUATION OF FIXED DOSE COMBINATIONS OF ANTI HYPERTENSIVE DRUGSAlladi Saritha,Vunnam Manoj*DOWNLOAD/VIEW
... Fixed dose drug combinations (FDCs), are combinations of two or more active drugs in a single dosage ...and Drug Administration, USA defines a combination product as ‘a product ...
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Development and Validation of a Novel Isocratic RP HPLC Method For Simultaneous Determination of Atenolol and Aspirin in Fixed dose combinations
... ultrasonicated for 20 min; the volume was then diluted to the mark and mixed well. A small portion was withdrawn and filtered through a 0.22 µm filter to ensure the absence of particulate matter. The filtered solution ...
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Do fixed dose combinations play an important role in the management of coexistent type two diabetes mellitus and hypertension?
... multiple drug therapy for the safe and effective management of coexistent TTDM and ...complex drug regimen leads to increased pill burden and often reflects into decreased patient ...complex drug ...
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Development and validation of RP HPLC method for simultaneous determination of metoprolol and aspirin in fixed dose combinations
... The pharmaceutical preparation containing aspirin 100 mg and metoprolol 50 mg was analyzed using this method. The content of 20 capsules was taken and powdered. The powder equivalent to 25 mg of aspirin and 12.5 mg of ...
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Comparitive Stability Studies on Rifampicin in Fixed Dose Combinations Between Blister and Strip Packaged Marketed Products
... There are several reasons for increasing incidence of tuberculosis with current increase in cases of HIV. Part of reason is the development of multi drug resistant tuberculosis mutants. Globally South East Asia ...
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Enhancement in Stabilityand In-Vivo Bioavailability of Rifampicin Alone and in Combination with Isoniazidusing Ascorbic Acid.
... of fixed dose combinations (FDC) tablets that ensures ingestion of all the components ...correct drug doses, FDC are expected to reduce the risk of emergency of drug resistant ...
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An evaluation of fixed dose combinations and it’s practices at medicine department of tertiary care hospital, Nepal
... combination drug was very much similar to each other, but their combination dosage was ...and dose are probably the marketing strategy of manufacturers to promote their ...specific dose of vitamins. ...
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Comparative analysis of the safety and tolerability of fixed-dose artesunate/amodiaquine versus artemether/lumefantrine combinations for uncomplicated <em>falciparum</em> malaria in pregnancy: a randomized open label study
... used fixed dose artemisinin-based combinations for the treatment of uncom- plicated Plasmodium falciparum malaria in the second and third trimester of ...standard fixed dose ...
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ASSESSMENT OF RATIONAL USE OF FIXED DOSE COMBINATION IN COMMUNITY PHARMACIES OF RESOURCE LIMITED SETTINGS OF ANDHRA PRADESH
... specific combinations. The main concept of rational drug therapy focuses on safety, efficacy and good quality of drug to be used in ...one dose combination drugs, two dose combination ...
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ASSESSMENT OF KNOWLEDGE, ATTITUDE AND PRACTICE OF PRESCRIBING FIXED DOSE COMBINATIONS AMONG POSTGRADUATE MEDICAL STUDENTS – A CROSS SECTIONAL SURVEY
... CIMS lists more than 100 irrational combinations which are not approved in any developed country but are being marketed in India. FDCs must be based on convincing therapeutic rationalization and be carefully ...
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<p>Effectiveness and Tolerability of LABA/LAMA Fixed-Dose Combinations Aclidinium/Formoterol, Glycopyrronium/Indacaterol and Umeclidinium/Vilanterol in the Treatment of COPD in Daily Practice – Results of the Non-Interventional DETECT Study</p>
... Objective and Methods: The main objective of the DETECT study was to investigate the impact of aclidinium/formoterol (AB/FF, b.i.d.), glycopyrronium/indacaterol (GLY/IND, q.d.) and umeclidinium/vilanterol (UME/VL, q.d.) ...
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Evaluating the role of atazanavir/cobicistat and darunavir/cobicistat fixed-dose combinations for the treatment of HIV-1 infection
... daily fixed-dose protease inhibitor combinations for the treatment of HIV-1 ...fewer drug–drug interactions, being devoid of anti-HIV-1 activity, as well as it has better solubility ...
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COMPARATIVE STUDY ON SAFETY AND EFFICACY OF CHLORZOXAZONE VERSUS THIOCOLCHICOSIDE IN COMBINATION WITH PARACETAMOL AND ACECLOFENAC IN PATIENTS WITH ACUTE LOW BACKACHE ASSOCIATED WITH MUSCLE SPASM
... The fixed dose combinations (FDCs) of muscle relaxants, non-steroidal anti-inflammatory drugs and paracetamol are commonly prescribed in the treatment of acute lower backache with muscle spasms Aim: ...
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Cost analysis of HIV treatment and drug-related adverse events when fixed-dose combinations of antiretrovirals (FDCs) were stopped, versus continuation with FDCs
... Emtricitabine and lamivudine are nucleoside analogue reverse transcriptase inhibitors, also known as “XTC” drugs. These two antiretroviral agents are similar in terms of structure, antiretroviral activity, and selection ...
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Management of hypertension with fixed dose combinations of candesartan cilexetil and hydrochlorothiazide: patient perspectives and clinical utility
... efficacy. Fixed drug–drug combinations of both principles like candesartan/hydrochlorothiazide (HCTZ) are highly effective in lowering blood pressure while providing improved compliance, a ...
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The Implications of Fixed Dose Combination (FDC) Compared to Single Pill Combinations (SPC): Based on Patients’ View
... adherence, drug-drug interactions and poly-pharmacy ...to drug-drug interactions is substantially increased when many drugs are taken ...
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