Fluorescence image-guided surgery
<p>IR780-loaded folate-targeted nanoparticles for near-infrared fluorescence image-guided surgery and photothermal therapy in ovarian cancer</p>
... Background and purpose: Surgery is regarded as the gold standard for patients with advanced ovarian cancer. However, complete surgical removal of tumors remains extremely challenging; fewer than 40% of patients ...
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A Tumor-Activatable Theranostic Nanomedicine Platform for NIR Fluorescence-Guided Surgery and Combinatorial Phototherapy
... cytoreductive surgery [5, ...[9]. Fluorescence image-guided surgery has a great potential for intraoperative detection of oncologic targets and real-time assessment of tumor borders, ...
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Image guided surgery: clinical validation of lesion identification technologies and exploration of nerve sparing approaches
... For the surgeons convenience, however, the radioguidance approach is often strengthened by optical guidance in the form of blue dye [5]. Unfortunately, blue dye also has some short-comings, the main ones being the ...
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A practical guide for the use of indocyanine green and methylene blue in fluorescence-guided abdominal surgery
... intraoperative image modality until specific tumor targets are ...colorectal surgery, using ICG due to its ...abdominal surgery, would be limited subject due to higher absorption and more nonspecific ...
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Image-guided surgery using invisible near-infrared fluorescent light : from pre-clinical studies to clinical validation
... The single-institution clinical trial was approved by the Medical Ethics Committee of the Leiden University Medical Center and was performed in accordance with the ethical standards of the Helsinki Declaration of 1975. A ...
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Image-guided surgery using near-infrared Turn-ON fluorescent nanoprobes for precise detection of tumor margins
... Cy5 fluorescence signal was resected until only a noise signal was detected in the surrounding ...underwent surgery under white light illumination only; the second group underwent IGS by the commercially ...
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Simultaneous Mapping of Pan and Sentinel Lymph Nodes for Real-Time Image-Guided Surgery
... can image all lymph nodes in the body in real time, or assess both the sentinel node and all nodes ...have fluorescence emission maxima either at 700 nm or at 800 ...
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Liver segment imaging using monocyte sequestration: a potential tool for fluorescence-guided liver surgery
... for image-guided liver surgery, it does not always provide a sufficient segment contrast and temporal stability because the dye disappears gradually after injection [13, ...liver surgery, at ...
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Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery
... NIR fluorescence probes for EphB4 targeted imaging using an EphB4 antibody ...NIR fluorescence-based imaging of colorectal cancer shows great potential for clinical use, especially for rectal ...for ...
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Pancreas-Targeted NIR Fluorophores for Dual-Channel Image-Guided Abdominal Surgery
... Intraoperative pancreas imaging and histology in rats. We compared T700-F with MB in SD rats by injecting 100 nmol of T700-F and 1.2 µmol (1.5 mg/kg) of MB, respectively (Figure 3A). Although MB high- lighted the ...
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Image , fluorescence and radio guided navigation for identification and localization of lymph node metastases in prostate cancer
... in image-guided surgery is the linkage of the pre-acquired images with the settings in a patient during ...the image acquisition, but other imaging modalities may be used as ...in image ...
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Recommendations for reporting on emerging optical imaging agents to promote clinical approval
... Intraoperative fluorescence imaging is particularly well-suited for surgical applications due to its inherently high sensitivity, resolution, and ability to provide images in ...of fluorescence has largely ...
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PSMA-targeting agents for radio- and fluorescence-guided prostate cancer surgery
... perform image-guided resection of tumor lesions ...YC-27 fluorescence-guidance developed a recurrence, whereas 40% of the mice with conventional white light resection developed recurrence within 30 ...
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Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology
... Sano et al. synthesized two probes, AlexaFlu- or680 conjugated panitumumab to target EGFR and ICG conjugated trastuzumab to target against HER2, to evaluate the feasibility of specifically detecting breast cancer cells ...
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A phase II trial of autologous dendritic cell vaccination and radiochemotherapy following fluorescence guided surgery in newly diagnosed glioblastoma patients
... enough to avoid progression in some cases, but it could still help to delay disease progression and to maximize the benefit of second-line therapies such as subsequent surgery or new chemotherapy. This type of ...
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A NSRS Detection Method for Ablation Needles in CT Images
... CT image-guided interventional surgery, the rapid and accurate positioning of ablation needle plays a key role in the smooth ...CT image-guided interventional surgery, a method ...
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Object oriented navigation using augmented reality: a new way of image guided surgery
... Pelvic fracture treatment demands appropriate treatment since adequate reconstruc- tions can prevent early total hip implantation [19]. Currently, preoperative surgical planning of fracture reduction moves more and more ...
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Weighted Guided Image Filtering
... edge-preserving image smoothing ...reconstructed image with respect to the image to be filtered while the regularization term provides the smoothness level of the reconstructed ...as guided ...
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MR guided endoscopic sinus surgery
... Summary: We describe an interactive, intraoperative im- aging-guided method for performing endoscopic sinus sur- gery (ESS) within a vertically open MR system. The pro- cedure was performed with intraoperative ...
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Comparison of corneal power obtained from VERION image-guided surgery system and four other devices
... implantation surgery, corneal curvature measure- ments for the right eye (115 eyes) of all subjects obtained with 5 different instruments were compared: the VERION Reference Unit, a LenStar LS900 optical ...
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