Fluticasone Propionate
The EFFECT trial: evaluating exacerbations, biomarkers, and safety outcomes with two dose levels of fluticasone propionate/formoterol in COPD
... of Fluticasone propionate/FormotErol in COPD Treatment) trial is a Phase III, 52-week, randomized, double-blind study to evaluate the efficacy and safety of two doses of fluticasone ...
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Clinical and economic outcomes for patients initiating fluticasone propionate/salmeterol combination therapy (250/50 mcg) versus anticholinergics in a comorbid COPD/depression population
... Methods: This retrospective, observational study used administrative claims of patients aged 40 years and older with COPD and comorbid depression/anxiety identified from January 1, 2004 through June 30, 2008. Patients ...
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Efficacy of Low-Dose Ciclesonide and Fluticasone Propionate for Mild to Moderate Persistent Asthma
... and fluticasone propionate 100 µg twice daily significantly improved asthma-specific quality of life as examined by the standardized ...to fluticasone propionate with regard to the ...
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A review of the clinical efficacy and safety of MP-AzeFlu, a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate, in clinical studies conducted during different allergy seasons in the US
... The clinical trial program for approval of a novel intra- nasal formulation of azelastine HCl (AZE, an antihistamine) 137 µg and fluticasone propionate (FP, a corticosteroid) 50 µg in a single spray ...
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The lung function profile of once-daily tiotropium and olodaterol via Respimat<sup>®</sup> is superior to that of twice-daily salmeterol and fluticasone propionate via Accuhaler<sup>®</sup> (ENERGITO<sup>®</sup> study)<div><br /></div>
... FEV 1 AUC 0–12 (primary end point), FEV 1 AUC 0–24 , and FEV 1 AUC 12–24 after 6 weeks of treatment were increased from baseline by 120 mL in all treatment arms, with greater increases at both dose levels of once-daily ...
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Lost in the Mist: Acute Adrenal Crisis Following Intranasal Fluticasone Propionate Overuse
... hand, fluticasone is known to have greater dose-related systemic bioactivity compared with other avail- able inhaled corticosteroids, particularly at doses above 800 micg inhaled via pressurized metered-dose ...
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ANALYTICAL STABILITY INDICATING UPLC ASSAY AND VALIDATION OF FLUTICASONE PROPIONATE IN NASAL SPRAY INHALER DOSAGE FORM
... Fluticasone propionate (99.80 % purity) used as analytical standard was procured from Spectrum Labs (Hyderabad). HPLC grade methanol, Acetonitrile (HPLC grade) was purchased from Qualigens fine chemicals, ...
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Long-Term Safety of Fluticasone Propionate and Nedocromil Sodium on Bone in Children With Asthma
... Methods. Children who were aged 6 to 14 years and had persistent asthma were randomized to 24 months’ treatment with fluticasone propionate (FP) 200 g/d or nedocromil sodium (NS) 8 mg/d (if uncontrolled, ...
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Development and Validation of Analytical Method for Simultaneous Estimation of Formoterol Fumarate Dihydrate and Fluticasone Propionate from Bulk and Dry Powder Inhaler Formulation
... The methods have been successively applied to simultaneous determination of Formoterol Fumarate Dihydrate & Fluticasone Propionate in dry powder Inhalation formulation. The methods were successfully ...
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Umeclidinium/vilanterol versus fluticasone propionate/salmeterol in COPD: a randomised trial
... twice-daily fluticasone propionate/salmeterol (FP/SAL) (500/50 mcg) over 12 weeks in patients with COPD with dyspnoea and without exacerbations in the year prior to ...
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Triple therapy with salmeterol/fluticasone propionate 50/250 plus tiotropium bromide improve lung function versus individual treatments in moderate-to-severe Japanese COPD patients: a randomized controlled trial – Evaluation of Airway sGaw after treatment with tripLE
... salmeterol/fluticasone propionate (FP) and tiotropium bromide is commonly used to treat chronic obstructive pulmonary disease (COPD), but sparse efficacy data exist in COPD patients with fewer symptoms and ...
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Development and evaluation of novel Fluticasone Propionate Emulgel for topical drug delivery
... DSC is a thermo analytical technique in which the difference in the amount of heat required to increase the temperature of a reference and sample are measured as a function of temperature. Both the sample and reference ...
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The role of fluticasone propionate/salmeterol combination therapy in preventing exacerbations of COPD
... of fluticasone propionate and salmeterol combination therapy (FSC) in the prevention of exacerbations of COPD as well as its related effects on lung function, survival, health status and quality of life, ...
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Fluticasone propionate/formoterol for COPD management: a randomized controlled trial
... As with pneumonia, other adverse events, biochemi- cal changes and acute pharmacodynamic effects showed no evidence of a dose response between the 500/20 µ g and 250/10 µ g FP/FORM dose levels. Similarly, from an ...
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DEVELOPMENT AND VALIDATION OF ULTRA PERFORMANCE LIQUID CHROMATOGRAPHIC METHOD FOR THE ANALYSIS OF PULMONARY DRUG PRODUCT CONTAINING FORMOTEROL FUMARATE AND FLUTICASONE PROPIONATE
... Accuracy of the method was determined in triplicate at three concentration levels 50 %, 100 % and 150 % of target assay concentration. Known quantities of drug substances corresponding to the specified level of the label ...
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Salmeterol plus fluticasone propionate versus fluticasone propionate plus montelukast: a randomised controlled trial investigating the effects on airway inflammation in asthma
... plus fluticasone propionate (FP) (Seretide™; SFC) and FP plus montelukast (FP/M) on sputum inflammatory markers, airway responsiveness, lung function, and symptoms in adult ...
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Comparison of fluticasone propionate and budesonide on COPD macrophage and neutrophil function
... Background: Inhaled corticosteroid use is associated with increased rates of pneumonia in COPD patients. The underlying mechanism is unknown, although recent data suggest that pneu- monia is more frequent in patients ...
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Seasonal allergic rhinitis: fluticasone propionate and fluticasone furoate therapy evaluated
... anti-leukotrienes. Fluticasone propionate is an established INS for the treatment of rhinitis, including ...established fluticasone propionate as an effective ...related fluticasone ...
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Fluticasone propionate-salmeterol versus inhaled corticosteroids plus montelukast: outcomes study in pediatric patients with asthma
... that fluticasone propionate-salmeterol was associ- ated with lower utilization of asthma-related health care services and costs compared with ICS + ...that fluticasone propionate- salmeterol ...
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Fluticasone Propionate Aqueous Nasal Spray Is Safe and Effective for Children With Seasonal Allergic Rhinitis
... To evaluate the efficacy and safety of fluticasone propionate aqueous nasal spray in children aged 4 to 11 years with seasonal allergic rhinitis.. Study design.[r] ...
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