foam cell
Insulin and glucose play a role in foam cell formation and function
... lipid-laden foam cells, largely derived from macrophages, with subsequent fatty streak ...formation. Foam cell formation, which is believed to be mediated by modified LDLs [5,6], often occurs in the ...
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Original Article Quercetin increases macrophage cholesterol efflux to inhibit foam cell formation through activating PPARγ-ABCA1 pathway
... of foam cells and increase the risk of developing ...different cell types, could elevate the development of foam cells formation in ...treated foam cells derived from oxLDL induced THP-1 cells ...
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Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation
... increased foam cell formation caused by the downregulation of ATP6V0E2 and autophagy due to increased nuclear translocation of ...macrophage foam cell formation, which represents a novel ...
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CXCL5 limits macrophage foam cell formation in atherosclerosis
... atherosclerosis, a chronic inflammatory vascular disease, has been largely unexplored. Using a mouse model of atherosclerosis, we found that CXCL5 expression was upregulated during disease progression, both locally and ...
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Role of Rab5 in the formation of macrophage-derived foam cell
... on foam cell maturation revealed that U937- derived macrophages produced significant increase in the accumulation of lipid droplet following the incubation of oxLDL as demonstrated by oil red O ...
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Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo
... motes chylomicron uptake by macrophages, and chy- lomicron remnants are known to promote cholesteryl ester accumulation by macrophages (14). The free fatty acids (FFA) produced by LPL-mediated hydrolysis can be ...
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Role of interleukin 1 beta in foam cell formation of THP 1 macrophages
... To investigate the effects of Interleukin-1beta(IL-1β) on foam cell formation of THP-1 macrophages (Mфs). Human THP-1 monocytes were differentiated into macrophages by phorbol esters in vitro, then the ...
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Hematopoietic arginase 1 deficiency results in decreased leukocytosis and increased foam cell formation but does not affect atherosclerosis
... in foam cell formation, the leukocytes in blood and spleen, the major hematopoietic organ and an important reservoir for monocytes, were analysed in the BM transplanted ...to foam cell ...
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New mechanism for foam cell generation in atherosclerotic lesions
... When similar amounts of free cholesterol were supplied with platelets, red blood cells RBC, RBC ghosts, or sonicated RBC, only platelets enhanced macrophage CE accumulation, which indica[r] ...
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Novel immune cell-based therapies for atherosclerosis
... of foam cells. Foam cell accumulation leads to fatty streaks ...C. Foam cells eventually die, resulting in the release of cellular debris and crystalline cholesterol, contributing to necrotic ...
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Anti-atherosclerotic activity of n-Hexane extract of Eleutherine americana Merr. on human macrophage primary cell culture
... efflux. Foam cell is marked by the presence of lipid deposits in the cytoplasm of macrophages which is microscopically visible with Oil Red O staining (red color) ...the foam cells was decreased in ...
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The evaluation of non-stochastic lattice structure on drop test application
... open foam cell (sponges) and closed foam cell ...open foam cell, every connected pore can be sealed whereas, in a closed foam cell can form an interconnected ...
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Mechanical behaviour and energy absorption performances of composite foam filled circular tubes under axial loadings
... weight. Foam is an excellent candidate for crashworthiness applications due the fact that it can undergo large plastic deformations at a nearly constant load (Avalle et ...the foam cell walls bend ...
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Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte generated reactive nitrogen species
... form foam cells is widely accepted as an index of the atherogenic potential of a ...However, foam-cell and fatty-streak for- mation are not necessarily ...both foam cells and fatty streaks are ...
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Overexpression of complement component C5a accelerates the development of atherosclerosis in ApoE-knockout mice
... of a high-fat diet, Ad-C5a injection produced more extensive lesions than control adenovirus, and its proathrosclerotic role was significantly blocked by C5a receptor antagonist. Immunohistochemical analysis showed ...
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Chymase in exocytosed rat mast cell granules effectively proteolyzes apolipoprotein AI containing lipoproteins, so reducing the cholesterol efflux inducing ability of serum and aortic intimal fluid
... proteolyzing human serum and human aortic intimal fluid, prevents these two physiologic fluids from effectively inducing cholesterol efflux from cultured macrophage foam cells. Inhibition was strongest when ...
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Optimization of Process Conditions for the Development of Tomato Foam by Box Behnken Design
... drying, foam mat dry- ing etc. Foam mat drying is one method which is gaining popularityand has been successfully applied to drying of tomato juice ...The foam mat drying is a process where a liquid ...
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Efficacy of ethanol based hand foams using clinically relevant amounts: a cross over controlled study among healthy volunteers
... of foam recommended on product labels for the post-contamination treatment of hands should be more precise, and address both the efficacy and a clinically acceptable time for drying after ...
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The Mechanical Properties and the Influence of Parameters for Metallic Closed-Cell Foam Subjected to High-Strain Rates
... Unlike the other simulations, the energy absorption related to the strain rate has a softening behaviour at higher strain rates. It is also noticed that as the strain rate increases, the difference between the solid peak ...
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The Effect of Aluminum Dihydrogen Phosphate on the Enhanced Mechanical Properties of Aluminum Foams
... Al foam with starch acetate as a space holder and to examine the effect of ADP on the compressive behavior of these foams till to ...Al foam using starch acetate as a filler material for desired ...
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