Forkhead transcription factor 1
Uterine receptivity and implantation: The regulation and action of insulin-like growth factor binding protein-1 (IGFBP-1), HOXA10 and forkhead transcription factor-1 (FOXO-1) in the baboon endometrium
... the transcription start site. [35]. The hepatocyte nuclear factor 1 (HNF1) binding region, insulin response element (IRE), gluoco- corticoid response element (GRE) and TATA element are highly ...
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Forkhead box transcription factor 1 expression in gastric cancer: FOXM1 is a poor prognostic factor and mediates resistance to docetaxel
... The expression of FOXM1 was detected through immu- nohistochemistry (IHC) analyses with 3-um-thick sec- tions of formalin-fixed and paraffin-embedded blocks. For IHC staining, tissue sections were dewaxed in xylene and ...
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Ocular forkhead transcription factors: seeing eye to eye
... (Zone 1), followed by a zone of proliferating neuroblast cells (Zone 2), a region of actively differ- entiating precursors (Zone 3), and, finally, post-mitotic neurons (Zone ...given factor in the retinal ...
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Regulation of Lysosomal Function by the DAF-16 Forkhead Transcription Factor Couples Reproduction to Aging in Caenorhabditis elegans
... gene transcription in the whole animal in vitro anal- ysis described above, we produced a line expressing a tran- scriptional reporter for vha-2 (Pvha-2::GFP) and individually assessed whether intestinal GFP ...
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The Forkhead Transcription Factor Fkh2 Regulates the Cell Division Cycle of Schizosaccharomyces pombe
... A 1:15 dilution of TAT1 antibody (Cancer Research UK) and a 1:50 dilution of fluorescein isothiocyanate (FITC)-conjugated anti-mouse sec- ondary antibodies (Sigma) were used as specified by the ...of ...
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Forkhead box transcription factor FOXO3a suppresses estrogen dependent breast cancer cell proliferation and tumorigenesis
... Although FOXO3a reportedly can suppress cell growth and tumorigenesis in ER-negative breast cancer cells [18,21], whether FOXO3a also regulates cell proliferation or tumori- genesis in ER-positive breast tumors is ...
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Forkhead Box Transcription Factor Regulation and Lipid Accumulation by Hepatitis C Virus
... box transcription factors play a role in modulating ex- pression of lipid ...after 1 day with siRNA for specific inhi- bition of FoxO1 or transfected with plasmid DNA for ectopic expression of ...
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The LXXLL motif of murine forkhead transcription factor FoxO1 mediates Sirt1 dependent transcriptional activity
... BML-210 inhibits FoxO1-dependent induction of a reporter construct under the control of an Igfbp-1 or G6Pase promoter. After hepatocytes were transfected with Igfbp-1/(p925GL3) (A) or G6Pase/luciferase ...
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Distal renal tubular acidosis in mice that lack the forkhead transcription factor Foxi1
... Some 40 mammalian forkhead genes are known today. Many of these genes play important roles during embryogenesis, for exam- ple, neuralization (Foxa2) (1), mesoderm induction (Foxf1) (2, 3), and kidney ...
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A Forkhead Transcription Factor Is Important for True Hyphal as well as Yeast Morphogenesis in Candida albicans
... reverse transcription in the presence of 5-(3-aminoallyl)-2⬘-deoxyuridine 5⬘-triphosphate ...experiment 1, one of two experiments is shown for experiment 2, and one of seven experiments is shown for ...
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The Fox/Forkhead transcription factor family of the hemichordate Saccoglossus kowalevskii
... Comparative studies among bilaterian lineages have previously identified 24 Fox families in bilaterians (FoxA to FoxS), including the newly identified FoxAB family [19-21,103]. Two of these families are ...
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The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose 6 phosphatase expression
... ative inhibitor of Foxo1-mediated transcription of an Igfbp-1 reporter construct containing an insulin response element (IRE) (refs. 40, 71 and our unpub- lished observation). In contrast, a ...
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The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth
... mice. After 4 hours, we removed and fixed pancreata in PBS (pH 7.4) con- taining 2% paraformaldehyde and embedded them in paraffin. We immunostained the sections with mouse anti-BrdU antibody (1:1,000). We ...
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Interaction of hookworm 14 3 3 with the forkhead transcription factor DAF 16 requires intact Akt phosphorylation sites
... HEK293 cells co-transfected with Ac-daf-16 and Ac-ftt-2 were lysed with 200 μL of cold buffer containing 50 mM NaCl, 50 mM Tris-HCl pH7.5, 0.1% NP-40, 5 mM EDTA, 1× Phosphatase Inhibitor Cocktail II (Calbiochem), ...
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Integrin engagement regulates monocyte differentiation through the forkhead transcription factor Foxp1
... Biosciences Inc. (San Diego, California, USA). Elongase enzyme mix, Super- Script II reverse transcriptase, Lipofectamine, and terminal deoxynucleo- tidyl transferase (TdT) were from Invitrogen Corp. (Carlsbad, ...
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Forkhead box transcription factor 1: role in the pathogenesis of diabetic cardiomyopathy
... causative factor in diabetes and linked with the occurrence of heart fail- ure in ...FOXO1 transcription factor as a central mediator of inflammation in the perspective of insulin resistance and ...
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Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo
... (TT+ 1 mg/kg-Vernodalin), Groups (IV) represent the high dose treatment of vernodalin in tumor bearing ani- mals (TT+ 10 mg/kg-Vernodalin), and Group (V) represent the Tamoxifen treatment in tumor bearing animals ...
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Mosaic analysis of insulin receptor function
... binding transcription factor 1 (Srebf1), glycogen synthase (Gys1), glycogen phosphorylase (Pygl), phosphofructokinase, liver (Pfkl), Foxo1, forkhead tran- scription factor-a2 (Foxa2), ...
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Activin induction of the ovine follicle-stimulating hormone beta-subunit is mediated by Smad4 and a forkhead box transcription factor
... upon transcription of its unique β-subunit, FSHB, which is carefully regulated by more than six reproductive ...growth factor-β (TGFβ) superfamily (2-5) and GnRH (6), whereas inhibin (6, 7) and follistatin ...
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Heat shock protein 70 down-regulates the production of toll-like receptor-induced pro-inflammatory cytokines by a heat shock factor-1/constitutive heat shock element-binding factor-dependent mechanism
... NF-κB transcription factor ...The transcription of Hsp70 is medi- ated by the activation of heat shock transcription factor- 1 (HSF-1), which binds to the heat shock ...
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