Formalin-Induced Pain
Involvement of endoplasmic reticulum stress in formalin-induced pain is attenuated by 4-phenylbutyric acid
... after formalin injection, using immunohistochemical analysis. Formalin injection induced a marked upregulation of BIP, ATF6 and c-fos in the ipsilateral superficial lumbar dorsal horn, whereas only ...
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The Effect of Acute Intra Locus Coeruleus (LC) Microinfusion of Bupropion on Formalin-Induced Pain Behavior in Rat
... the pain reliever for over 40 ...the formalin-induced pain behavior. The pain killing effects of antidepressants have been totally stud- ied and reviewed (Thaler et ...The ...
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Central Effect of Exogenous Histamine on Pain Induced by Sub-Plantar Injection of Formalin in Rabbits
... effect induced by SKF 91488, an inhibitor of histamine catabolism, was prevented by chlorpheniramine ...trigeminal pain, the preventive effect of ranitidine, but not chlorpheniramine on the histamine- ...
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Analgesic Appraisal of Bidens pilosa (Asteraceae) Leaf Extracts Used in Management of Oral Lesion Pain in HIV/AIDS Patients in Rodents
... managing pain asso- ciated with oral lesions of HIV/AIDS patients in South Western ...mice, formalin-induced pain and tail flick methods in ...acid induced pain, non dose ...
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Anti-inflammatory and analgesic activity of different fractions of Boswellia serrata
... carrageenan induced paw edema, acetic acid induced writhing response, formalin induced pain, hot plate and tail flick method for studying anti-inflammatory and analgesic activity, ...
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Anti-Rheumatic and Antioxidant activity of extract of Stem bark of Ficus bengalensis
... Adjuvant induced arthritis model, the Formalin induced arthritis model and the Agar induced arthritis ...of Formalin- induced pain ...
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83. Anti-inflammatory and antioxidants properties of the ethanolic stem bark extract of Cordia africana Lam.
... Cordia africana Lam. (Boraginaceae), a widely known shade tree, is used in Northern Nigeria and East Africa for the management of haemorrhoids, headache and fatigue, respectively. In this study, the ethanolic stem bark ...
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Capsazepine, a Transient Receptor Potential Vanilloid Type 1 (TRPV1) Antagonist, Attenuates Antinociceptive Effect of CB1 Receptor agonist, WIN55,212-2, in the Rat Nucleus Cuneiformis
... experiments, formalin test, two-way ANOVA for repeated measures over time fol- lowed by Bonferroni’s test for obtained pain score val- ues [treatment main effect: ...in formalin-induced ...
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The Effect of the Histaminergic System on the Nociceptive Response to Plantar Injection of Formalin in Rats
... the local mediators of inflammation which plays a role in both of the phases of formalin-induced pain (12). On the other hand, the histaminergic system is one of the four aminergic system of the ...
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Effect of pilocarpine on the formalin-induced orofacial pain in rat
... orofacial pain in ...orofacial pain was induced by SC injection of a diluted formalin solution (1%, 50 μL) in the right upper lip, and the time spent face rubbing was measured in five min ...
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Effects of Extremely Low Frequency Magnetic Field (ELF MF) on Formalin Induced Chronic Pain in Mice
... The findings of this study correlates with other original basic research on analgesic effect of different fre- quencies of electromagnetic fields that were performed on rats and snails. Some clinicians tried low ...
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Role of C-fibers in pain and morphine induced analgesia/hyperalgesia in rats.
... opioid dosage will be reached to such mentioned ultra low dose pharmacokinetically. Thus, any insight in to the mechanism of opioids-ultra low dose action on pain by investigation can help us to find probable ways ...
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Antinociceptive Effect of Morphine Microinjections into the Dorsal Hippocampus in the Formalin-Induced Orofacial Pain in Rats
... of formalin into the upper lip produced a distinct biphasic pattern in the face rubbing performed by ipsilateral ...of formalin 1 % and 1.5% into the upper lip induced a biphasic pattern in the face ...
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Antinociceptive Activities of Acetone Leaves Extracts of Carissa Spinarum and Caesalpinia Volkensii in Mice
... Generally, most opioids exert their analgesic effects through µ-receptor binding in the central nervous system. Opioids may also bind to opioid receptors in the periphery, when they are present (Stein and Lang, 2009). ...
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Analgesic and Anti-inflammatory Activity of Heartwood of Aquilaria Agallocha in Laboratory Animals
... ANOVA revealed that pretreatment with EAA (50, 100 and 200 mg/kg) showed significant (p < 0.05) reduction in number of writhes in dose dependent manner (Table 2). EAA at doses of 50, 100 and 200 mg/kg caused a ...
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Inhibition of Cyclooxygenase Type 1 and 2 Enzyme by Aqueous Extract of Elaeagnus Angustifolia in Mice
... of formalin in plantar part of right ...to formalin injection were evaluated by observers as 0 to 3 score depending on the animal’s foot ...of formalin, while naloxone and memantine were injected to ...
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Antipyretic, antiinflammatory and antinociceptive activities of four selected Kenyan medicinal plants in Mice models
... infection and excessive UV radiation. Resveratrol has also been found to have significant anti-mutation, anti-inflammatory, antioxidant and DNA protective actions, when consumed by animals and humans. Most of the active ...
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ANTINOCICEPTIVE AND ANTI INFLAMMATORY ACTIVITIES OF THE AQUEOUS EXTRACT OF MIKANIA LINDLEYANA IN RODENTS
... was induced according to a previously described procedure 10 ...was induced by application of 20 µL of an acetone solution containing the irritant agent ...
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Involvement of Endogenous Opioid System in Swim Stress-Induced Pain Modulation During the Interphase of the Formalin Test
... the formalin test in animals without swim stress compared to the con- trol ...the formalin test (Azh- dari-Zarmehri, Mohammadzadeh, Feridoni, & Nazeri, ...the formalin test. Conversely, it pro- ...
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ANTI-NOCICEPTIVE ACTIVITIES AND TOXICOLOGICAL PROFILE OF AQUEOUS EXTRACT OF LEAVES OF HIBISCUS ASPER
... This test was carried out according to the method described by Vogel and Vogel (4).One hour after administration of each treatment the solution of acetic acid (1%) was administered by intra-peritoneal route (0.1 ml per ...
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