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Framingham Heart Study

Longitudinal trends in the association of metabolic syndrome with 550 k single nucleotide polymorphisms in the Framingham Heart Study

Longitudinal trends in the association of metabolic syndrome with 550 k single nucleotide polymorphisms in the Framingham Heart Study

... [3]. Framingham Heart Study (FHS) is one of the best-known cohort studies of cardiovascular disease that has demonstrated an association between cardiovascular risk factors and cardiovascular disease ...

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Genome wide association analysis of cardiovascular related quantitative traits in the Framingham Heart Study

Genome wide association analysis of cardiovascular related quantitative traits in the Framingham Heart Study

... 2. Cupples LA, Arruda HT, Benjamin EJ, D ’ Agostino RB Sr, Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, Kiel DP, Laramie JM, Larson ...

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Region based analysis in genome wide association study of Framingham Heart Study blood lipid phenotypes

Region based analysis in genome wide association study of Framingham Heart Study blood lipid phenotypes

... Due to the high-dimensionality of single-nucleotide polymorphism (SNP) data, region-based methods are an attractive approach to the identification of genetic variation associated with a certain phenotype. A common ...

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Association of 25-Hydroxyvitamin D status and genetic variation in the vitamin D metabolic pathway with FEV1 in the Framingham Heart Study

Association of 25-Hydroxyvitamin D status and genetic variation in the vitamin D metabolic pathway with FEV1 in the Framingham Heart Study

... the Framingham Heart Study of the National Heart Lung and Blood Institute of the National Institutes of Health and Boston University School of ...Medicine. Framingham Heart ...

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Classification tree for detection of single nucleotide polymorphism (SNP) by SNP interactions related to heart disease: Framingham Heart Study

Classification tree for detection of single nucleotide polymorphism (SNP) by SNP interactions related to heart disease: Framingham Heart Study

... this study was to detect the effect of interactions between single-nucleotide polymorphisms (SNPs) on incidence of heart ...the Framingham Heart Study (FHS) were ...coronary ...

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A comparison of time dependent Cox regression, pooled logistic regression and cross sectional pooling with simulations and an application to the Framingham Heart Study

A comparison of time dependent Cox regression, pooled logistic regression and cross sectional pooling with simulations and an application to the Framingham Heart Study

... under study and are known only when the individual remains in the study as event-free and is ...our Framingham Heart Study example given the clinical interest in the relation- ship ...

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Comparison of a unified analysis approach for family and unrelated samples with the transmission disequilibrium test to study associations of hypertension in the Framingham Heart Study

Comparison of a unified analysis approach for family and unrelated samples with the transmission disequilibrium test to study associations of hypertension in the Framingham Heart Study

... this study, we compared FamCC and the TDT using data on hypertension, SBP, and DBP in the Framingham Heart Study ...Our study indicated FamCC has reasonable type I ...

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Detection of imprinting and heterogeneous maternal effects on high blood pressure using Framingham Heart Study data

Detection of imprinting and heterogeneous maternal effects on high blood pressure using Framingham Heart Study data

... Both imprinting and maternal effects could lead to parent-of-origin patterns in complex traits of human disorders. Statistical methods that differentiate these two effects and identify them simultaneously by using ...

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Addition of Inflammatory Biomarkers Did Not Improve Diabetes Prediction in the Community: The Framingham Heart Study

Addition of Inflammatory Biomarkers Did Not Improve Diabetes Prediction in the Community: The Framingham Heart Study

... present study was conducted in the Framingham Heart Study, a community-based, observational epidemiological ...the Framingham Offspring study have been ...of Framingham, ...

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Metabolic syndrome and inflammatory biomarkers: a community-based cross-sectional study at the Framingham Heart Study

Metabolic syndrome and inflammatory biomarkers: a community-based cross-sectional study at the Framingham Heart Study

... This study was funded by the National Heart, Lung, and Blood Institute ’ s Framingham Heart Study N01-HC-25195; and by RO1-HL076784, RO1- HL064753, and R01-AG028321, the National ...

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Genome wide association analysis of Framingham Heart Study data for the Genetics Analysis Workshop 16: effects due to medication use

Genome wide association analysis of Framingham Heart Study data for the Genetics Analysis Workshop 16: effects due to medication use

... the Framingham Heart Study using several measured variables including causal genes (based on a 500 k SNP panel), smoking, dietary intake, and medication ...

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Genome wide association study for empirically derived metabolic phenotypes in the Framingham Heart Study offspring cohort

Genome wide association study for empirically derived metabolic phenotypes in the Framingham Heart Study offspring cohort

... The Framingham Heart Study (FHS) is an ongoing longitudinal study focusing on the development of coronary heart disease and associated risk factors in Framingham, ...in ...

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Multivariate association analysis of the components of metabolic syndrome from the Framingham Heart Study

Multivariate association analysis of the components of metabolic syndrome from the Framingham Heart Study

... FHS: Framingham Heart Study; HDL: High- density lipoprotein; IBD: Identity by decent; LD: Linkage disequilibrium; MetSyn: Metabolic syndrome; QTL: Quantitative trait locus; SBP: Systolic blood ...

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Erythrocyte n-6 Fatty Acids and Risk for Cardiovascular Outcomes and Total Mortality in the Framingham Heart Study

Erythrocyte n-6 Fatty Acids and Risk for Cardiovascular Outcomes and Total Mortality in the Framingham Heart Study

... coronary heart disease in families. The Framingham offspring study, American journal of epidemiology, ...National Heart, Lung, and Blood Institute's Framingham Heart ...

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Evaluation of genetic risk scores for lipid levels using genome wide markers in the Framingham Heart Study

Evaluation of genetic risk scores for lipid levels using genome wide markers in the Framingham Heart Study

... This study has several ...the Framingham Heart Study data. In a study based on these data, some of the authors report in another GAW16 paper [14] that even though a naïve approach is ...

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A genome wide association analysis of Framingham Heart Study longitudinal data using multivariate adaptive splines

A genome wide association analysis of Framingham Heart Study longitudinal data using multivariate adaptive splines

... 4. Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, Ikeda M, West K, Kashuk C, Akyol M, Perz S, Jalilzadeh S, Illig T, Gieger C, Guo CY, Larson MG, Wichmann HE, Marbán E, O ’ Donnell CJ, Hirschhorn JN, Kääb S, ...

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Reproducibility of a novel computed tomography based measurement of renal papillary density in the Framingham Heart Study

Reproducibility of a novel computed tomography based measurement of renal papillary density in the Framingham Heart Study

... The feasibility and reproducibility of measuring RPD using CT has not been well studied. A robust technique for an accurate, non-invasive measurement of RPD could provide important information about current kidney health ...

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Changes in the food environment over time: examining 40 years of data in the Framingham Heart Study

Changes in the food environment over time: examining 40 years of data in the Framingham Heart Study

... This study had several limitations. Due to the extensive effort to identify historical food establishments, the study area included only four major towns of the Framingham Heart Study. ...

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Correlation of renin angiotensin and aldosterone system activity with subcutaneous and visceral adiposity: the framingham heart study

Correlation of renin angiotensin and aldosterone system activity with subcutaneous and visceral adiposity: the framingham heart study

... Generation Framingham Heart Study participants underwent multidetector computed tomography assessment of SAT and VAT volumes during Exam 1 (2002 and ...

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Defining genetic determinants of the Metabolic Syndrome in the Framingham Heart Study using association and structural equation modeling methods

Defining genetic determinants of the Metabolic Syndrome in the Framingham Heart Study using association and structural equation modeling methods

... the Framingham Heart Study (Offspring Cohort, Exam 7) using the Affymetrix 50 k Human Gene Panel and three different approaches: 1) an association-based “ one-SNP- at-a-time ” analysis with MetSyn as ...

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