fructose 1,6-bisphosphate
Effects of Depleting the Essential Central Metabolic Enzyme Fructose-1,6-Bisphosphate Aldolase on the Growth and Viability of Candida albicans: Implications for Antifungal Drug Target Discovery
... The central metabolic enzyme fructose-1,6-bisphosphate aldolase (Fba1p) catalyzes a reversible reaction required for both glycolysis and gluconeogenesis. Fba1p is a potential antifungal target because it is ...
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Fructose 1, 6 Bisphosphate Aldolase from Gestational Diabetic Human Placenta: Purification, Identification, and Investigation of Kinetic Properties
... It is estimated that there may be a modification in the enzyme structure of placental cells for low concentrations of fructose 1,6-bisphosphate. Previous studies showed that human muscle, liver, and brain ...
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Healthy and Gestational Diabetic Human Placental Fructose 1,6 Bisphosphate Aldolase; Comparative Investigation of Kinetic Properties and Inhibition Effects of DHAP, ATP, and Mg+2 ion
... The 1-phosphate binding side of FBPA is consist by Arg 148 and Lys 146 ...The 6-phosphate binding side is made up by Lys 41, Arg ...residue. Fructose 1,6 bisphosphate which substrate of FBPA, ...
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Gene Replacement of Fructose-1,6-Bisphosphate Aldolase Supports the Hypothesis of a Single Photosynthetic Ancestor of Chromalveolates
... hypothesis. Fructose-1,6-bisphosphate aldolase (FBA) is a glycolytic and Calvin cycle enzyme that exists as two nonhomologous types, class I and class ...
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Fructose-1,6-bisphosphate aldolase encoded by a core gene of Mycoplasma hyopneumoniae contributes to host cell adhesion
... Mycoplasma hyopneumoniae is an important respiratory pathogen that causes great economic losses to the pig industry worldwide. Although some putative virulence factors have been reported, pathogenesis remains poorly ...
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Gas chromatography-mass spectrometry based serum metabolic analysis for premature infants and the relationship with necrotizing enterocolitis: a cross-sectional study
... Pearson correlation analysis, of differential metabolites and clinical test indicators, suggests that the changes in metabolites are related to the changes of clinical indica- tors. The ROC and AUC analyses showed that ...
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Gluconeogenic Fructose 1, 6-bisphosphatase from Ginkgo biloba L.: Isolation and characterization
... The cytosolic FBPase from Ginkgo biloba leaves utilized D-fructose-1,6- bisphosphate (FBP) as its specific substrate. However, this enzyme showed traces of activity in presence of ...
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Partial purification and characterisation of cytosolic Fructose-1, 6-bisphosphatase from Drymaria cordata
... of fructose-1,6-bisphosphate to fructose-6- phosphate and inorganic phosphate in the presence of divalent cations such as magnesium, manganese or zinc (Dzugaj, ...
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Hypertrehalosaemic neuropeptides decrease levels of the glycolytic signal fructose 2,6 bisphosphate in cockroach fat body
... of fructose 2,6-bisphosphate brings about a decrease in the activity of phosphofructokinase in vitro (see ...in fructose 2,6-bisphosphate level would be physiologically significant only if a ...
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Diagnostic value of immunoglobulin G antibodies against Candida enolase and fructose bisphosphate aldolase for candidemia
... for 1 h at 37°C. Sera were diluted 1:500 in PBS-T and assayed in triplicate (100 ...After 1 h at 37°C, wells were washed three times with ...a 1:10,000 di- lution of horseradish peroxidase ...
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Diets involved in PPAR and PI3K/AKT/PTEN pathway may contribute toneuroprotection in a traumatic brain injury
... A wide variety of compounds have been identified as per- oxisome proliferator-activated receptor (PPAR) ligands. The n-3 PUFAs have a beneficial effect on most of the metabolic risk factors by regulating gene ...
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FRUCTOSE IN THE TREATMENT OF DIABETIC KETOSIS
... Miller and his associates 4, 30 have demonstrated that: 1 There is a large hepatic uptake of fructose in diabetic patients deprived of insulin; 2 some of the fructose is converted to glu[r] ...
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Fructose metabolism in humans – what isotopic tracer studies tell us
... of fructose to glu- cose as compared between men and ...a fructose-containing beverage (3x0.3 g/kg bw), 37.4% of the fructose was converted to glucose in men during 6 ...equal fructose ...
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Assembly and Replication of HIV-1 in T Cells with Low Levels of Phosphatidylinositol-(4,5)-Bisphosphate
... The 74LR mutation enhanced an entry or early postentry step, as is evident from increased viral DNA synthesis in T cells (Fig. 8A to C). This effect of the 74LR change may be ac- counted for by one of several mechanisms ...
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Early and reversible changes to the hippocampal proteome in mice on a high-fat diet
... Unlike PA, challenge with DHA did not change den- dritic morphology and when administered at the same time as PA, DHA protected against the effects of PA. Several mechanisms may underlie this effect. Cell studies have ...
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Monocarboxylate transporter 1 promotes classical microglial activation and pro-inflammatory effect via 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3
... Microglia, the tissue-resident macrophages in the central nervous system (CNS), play important roles in phagocyt- osis, cell migration, antigen presentation, and cytokine production [1]. Accumulated evidences have ...
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Fructose-1, 6-diphosphate (FDP) as a novel antidote for yellow oleander-induced cardiac toxicity: A randomized controlled double blind study
... Atropine is the most widely used agent in treating ole- ander induced bradyarrhythmias [1]. However there is no evidence of any benefit of atropine in such conditions [23]. Patients with slow heart rate (below 40 ...
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Journal of Applied Pharmaceutical Science
... The expressions of the genes on the 42 nd hr and 84 th hr after the challenge with the virus were examined to find out whether the plant isolate (MP07X) was inhibiting the processes involved in the viral multiplication ...
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Multiscale Simulations of Phosphatidylinositol Bisphosphate: Understanding Its Biological Role Through Physical Chemistry
... from 1 at a given value of r means there is excess density of that interaction pair at r relative to bulk and at small distances, g (r ) → 0 because two atoms cannot occupy the same ...
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GLUT5-mediated fructose utilization drives lung cancer growth by stimulating fatty acid synthesis and AMPK/mTORC1 signaling
... vivo fructose utilization mediated by GLUT5 stimulates fatty acid synthesis and palmitoleic acid ...impaired fructose utilization caused by SLC2A5 deletion on fructose input, fructose-derived ...
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