fungal pathogenesis
A Pathogenesis Assay Using Saccharomyces cerevisiae and Caenorhabditis elegans Reveals Novel Roles for Yeast AP-1, Yap1, and Host Dual Oxidase BLI-3 in Fungal Pathogenesis
... Our studies have demonstrated that ROS play a central role in mediating host-pathogen interactions in our model. Using our novel pathogenesis assay with S. cerevisiae as a model pathogen and C. elegans as the ...
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Hypoxia and Fungal Pathogenesis: To Air or Not To Air?
... albicans pathogenesis, as the yeast-to-hypha switch is generally thought to be a major virulence attribute of this or- ...in fungal hypoxia adaptation that have been largely unexamined (39, 81, ...of ...
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Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis
... All three chitin deacetylases share similar protein sequence motifs for a cleavable N-terminal signal sequence and for C-terminal addition of a glycosylphosphatidylinosi- tol (GPI) anchor. C. neoformans Cda2 (initially ...
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Parallels in Fungal Pathogenesis on Plant and Animal Hosts
... opportunistic fungal infec- tions in humans, pathogenicity mechanisms in plant pathogens were better understood than those in animal ...of fungal pathogenesis in both animals and ...more ...
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Rad53 and Chk1 Dependent DNA Damage Response Pathways Cooperatively Promote Fungal Pathogenesis and Modulate Antifungal Drug Susceptibility
... Here we demonstrated that both the Rad53-dependent and Chk1-dependent path- ways contribute to the pathogenicity of C. neoformans. Although the role of DNA damage response pathways in fungal pathogenicity has been ...
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Mitochondria and Fungal Pathogenesis: Drug Tolerance, Virulence, and Potential for Antifungal Therapy
... While recent studies have highlighted the importance of mitochondrial function for tolerance of antifungal drugs and for virulence, our understanding of the roles of this organelle in human fungal pathogens is ...
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A Novel Virulence Phenotype Rapidly Assesses Candida Fungal Pathogenesis in Healthy and Immunocompromised Caenorhabditis elegans Hosts
... Here we utilized a C. elegans experimental host system to identify novel measures of host fitness associated with fungal infection. By tracking the number of progeny produced per day, we can quickly and ...
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Mitogen-Activated Protein Kinase Pathways and Fungal Pathogenesis
... cerevisiae. Fungal pathogens may have novel receptors for sensing host and environmental signals to regulate penetration and infec- tious ...sequenced fungal genomes lack significant homologs of receptor ...
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A conserved fungal glycosyltransferase facilitates pathogenesis of plants by enabling hyphal growth on solid surfaces
... some fungal species use a different protein, or mechanism, to provide the equivalent ...of fungal pathogenesis likely derived “inadvertently” from an ancient requirement for fungi to evolve the ...
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Experimental models of cryptococcosis
... 4.2.1. Mouse (Mus musculus). The majority of Cryptococcus- related work utilising mammalian systems has been carried out using mice. Due to the fact that murine models are well established as valuable study systems in ...
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Prevalence of fungal infection in nasal polyposis - A cross-sectional study, conducted at a tertiary care hospital in Karachi
... Prevalence of the disease is related to environment as well as individual host conditions. People of low socioeconomic group living in overcrowded and damp environment, suffer the most. It involves both sexes and all age ...
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Arginine Is a Critical Substrate for the Pathogenesis of Pseudomonas aeruginosa in Burn Wound Infections
... Furthermore, severe burn trauma causes devascularization of the wound environ- ment, which prevents neutrophils and other innate effector cells from migrating into the wound and clearing the bacterial infection. The ...
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Cytochrome bd Dependent Bioenergetics and Antinitrosative Defenses in Salmonella Pathogenesis
... detoxification of host-derived NO. Our investigations indicate that, together with Hmp, cytochrome bd is an important compo- nent of the adaptive antinitrosative arsenal of Salmonella in vivo. Our biochemical and ...
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ISOLATION AND IDENTIFICATION OF PHYTO HORMONE FROM WHEAT GRASS FUNGUS
... Indole acetic acid (IAA) production is major properties of certain funguses that stimulates and facilitate plant growth. The present work deals with isolation, characterization and identification of indole acetic acid ...
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Fungal rhinosinusitis
... Fungal infections in both their invasive and non-invasive forms can prove difcult to diagnose. The often characteristic appearances on imaging are of great assistance. CT is the primary imaging modality and is ...
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AN UPDATE ON NOVEL TECHNOLOGIES, IN VITRO AND IN VIVO MODELS FOR TUBERCULOSIS AND TUBERCULOUS MENINGITIS
... the pathogenesis of pulmonary tuberculosis followed by the pathogenesis of tuberculous meningitis wherein the bacteria first enter to the lungs which then form into macrophages, these macrophages form into ...
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BIOLOGICAL DIVERSITY OF ENDOPHYTIC FUNGI ISOLATED FROM UNDERGROUND PARTS OF INDIAN MEDICINAL PLANTS
... Mature, healthy plant materials were collected and identified by expertise from Department of Botany, Moolji Jaitha College Jalgaon, India. Collected plant samples were immediately brought to laboratory and were used ...
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Fungal Colonization in the Very Low Birth Weight Infant
... 1986;78:225-232; fungal colonization, fungal sepsis, Can- dida, urinalysis, very low birth weight infant.. Fungal infections affect 3% to 4% of very low.[r] ...
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A Study of Post Transplant Pulmonary Infections.
... Tuberculosis Atypical mycobacteria Fungal infections Mucor, candida Fungal infections candida Polymicrobial infections.[r] ...
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A Case of Severe Eosinophilia in a Preterm Infant
... In children, the main causes of eosino- philia include allergies and parasitic infestations. In rare cases it may be associated with some fungal or viral infections, malignant tumors, gastro- enteritis, or ...
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