Fusion loop
Mutagenesis of Varicella-Zoster Virus Glycoprotein B: Putative Fusion Loop Residues Are Essential for Viral Replication, and the Furin Cleavage Motif Contributes to Pathogenesis in Skin Tissue In Vivo
... Immunoprecipitation of gB from transfected or infected cells showed that the membrane-anchored COOH terminal and the distal NH 2 terminal remain associated since MAb 158 is known to precipitate gB in its native ...
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Mechanistic Study of Broadly Neutralizing Human Monoclonal Antibodies against Dengue Virus That Target the Fusion Loop
... intracellular fusion, not virus-cell ...conserved fusion loop region of E domain II. Mutations at fusion loop residues W101, L107, and/or G109 significantly reduced the binding of the ...
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A Fusion-Loop Antibody Enhances the Infectious Properties of Immature Flavivirus Particles
... of fusion-loop antibodies, such as E53, to neutralize infection ...that fusion-loop MAbs preferentially recognize immature particles (3), the decreased neutralizing activity of E53 with fully ...
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Ebolavirus Entry Requires a Compact Hydrophobic Fist at the Tip of the Fusion Loop
... membrane fusion is an essential step in the life cycle of every enveloped ...brane fusion is the interaction of viral fusion peptides or fusion loops, found in all viral fusion ...
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Distinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion loop
... Figure 1 Sequence alignment of fusion loop domain of E proteins from different flaviviruses, WNV E: West Nile virus wild type E-protein, WNV-Equad: WNV E-quadruple mutant point mutations[r] ...
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A Polymorphism within the Internal Fusion Loop of the Ebola Virus Glycoprotein Modulates Host Cell Entry
... Plasmids. Expression plasmids for the glycoproteins of the EBOV from the 1976 outbreak in the Democratic Republic of Congo (Mayinga variant, EBOV1976-GP, GenBank accession number AF086833.2), Ebola ...
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HSV Glycoprotein B Fusion Loop Architecture and Mechanisms of Fusion Inhibition
... Herpes simplex virus (HSV) entry into host cells requires the function of the viral envelope glycoprotein (g) B in concert with three other envelope proteins, namely gD and the complex of gH/gL. Glycoprotein D functions ...
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A Conserved Histidine in the ij Loop of the Semliki Forest Virus E1 Protein Plays an Important Role in Membrane Fusion
... the fusion loop interacts with cholesterol- containing target membranes, and that prevention of this in- teraction by a MAb to the fusion loop prevents E1-membrane association (1, ...ij ...
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A Key Interaction between the Alphavirus Envelope Proteins Responsible for Initial Dimer Dissociation during Fusion
... membrane fusion protein, is an elongated molecule containing 3  -sheet-rich domains (DI to DIII), with the conserved hydrophobic fusion loop at the membrane distal tip (6, ...the fusion ...
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Second-Site Revertants of a Semliki Forest Virus Fusion-Block Mutation Reveal the Dynamics of a Class II Membrane Fusion Protein
... the fusion loop at the tip, the second elongation of domain II in yellow with the cd loop at the tip, the linker between domains I and III in purple, domain III in blue, and the N-terminal portion of ...
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Capturing the Herpes Simplex Virus Core Fusion Complex (gB-gH/gL) in an Acidic Environment
... gB fusion loop mutant proteins that do not bind membranes (26), we hypothesize that gH/gL can float only with liposomes by association with gB at pH 5; ...correct fusion loops and that fusion ...
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pnas.201812055.pdf
... cross-reactive, fusion loop-directed mAbs and heterotypic immune sera (from primary DENV2 and DENV3 patients) efficiently neutralized cell culture viruses but not the human plasma ...The fusion ...
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Role of Conserved Histidine Residues in the Low-pH Dependence of the Semliki Forest Virus Fusion Protein
... virus fusion proteins pro- posed histidines as critical components of the pH ...dependent fusion reactions of viruses with class I fusion proteins (39, 44) and class III fusion proteins (4, ...
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The Design for the Boiler Drum Level System Based on Immune Control
... Cascade control is widely used in power plant. deputy loop acts as a "coarse" role, while main circuit is used to perform "fine tune". The effect of two regulators in cascade control system is ...
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1. Real time fusion of gestures
... When Fusion of two audiovisual segments are involved, then audio sample and a video frame will be selected first, the fused points are referred as ...the fusion of audio track and video track when the ...
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Structural implications of RNA dimerization in a gamma retrovirus
... stable loop- loop interactions independently of other RNA ...initial loop-loop interaction is converted to a high affinity, but less selective, interaction in the final dimer ...
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1. Policy analysis in higher technical education-a system dynamic modeling
... causal loop diagram of Placement sector of higher technical education system showing its impact on quality of the ...The loop has got two reinforcing loop R1,R2 and balancing loop ...
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loops.pdf
... loop. Body of loop is first executed, then test condition is checked. If test condition is true, loop is repeated, if it is false, loop terminates.. ¾ Body of loop will always be[r] ...
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A Peptide Pertaining to the Loop Segment of Human Immunodeficiency Virus gp41 Binds and Interacts with Model Biomembranes: Implications for the Fusion Mechanism
... viral fusion process in addition to the other membrane-perturbing domains (12, 14, 26, 33, 34, 35, 38, 44, ...the fusion process, we have studied a peptide of 35 amino acids, analogous to residues 579 to ...
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Gluon fusion contribution to HBB (B = H, γ, Z) at the LHC
... Abstract. We have calculated one-loop amplitudes for the production of Higgs boson in association with two electroweak bosons (H, γ, Z) via gluon-gluon fusion. We present preliminary results for the total ...
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