Fusion Protein
Theoretically Analysis of Fusion Protein, Sequence and Folding
... on fusion protein, researchers improved that the longer linker is better for protection the folding and biological activity and can be cleaves by cellular protease, these features promote investigators to ...
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The Fusion Loops of the Initial Prefusion Conformation of Herpes Simplex Virus 1 Fusion Protein Point Toward the Membrane
... of fusion when expressed on the surface of eukaryotic cells ...the fusion protein adopts an intermediate conformation in which the molecule is completely extended (termed the extended intermediate), ...
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Regulation of Paramyxovirus Fusion Activation: the Hemagglutinin-Neuraminidase Protein Stabilizes the Fusion Protein in a Pretriggered State
... Viral fusion is driven by specialized pro- teins that undergo an ordered series of conformational changes resulting in the close apposition of the viral and host membranes and the formation of a fusion pore ...
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Cloning, Expression and Characterization of Recombinant Exotoxin A-Flagellin Fusion Protein as a New Vaccine Candidate against Pseudomonas aeruginosa Infections
... (fliC) fusion protein as a cocktail antigen was expressed and purified and its antigenic characteristics were ...recombinant fusion protein by ...exoA-fliC fusion protein in high ...
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The Human Metapneumovirus Fusion Protein Mediates Entry via an Interaction with RGD-Binding Integrins
... cell-cell fusion, although the authors suggested that the G protein might enhance fusion in certain cell types ...F-mediated fusion, we analyzed VLP fusion ...R18-F-VLP fusion ...
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Chen, Ying (2006): In vivo detection of the BCR/ABL1 protein: towards a new therapeutic strategy for fusion protein associated leukemias. Dissertation, LMU München: Medizinische Fakultät
... CRKL protein. In contrast to the BAP-1 protein, which is the substrate of the BCR serine-threoine kinase, the CRKL protein is the substrate of the ABL1 tyrosine kinase (Oda, Heaney et ...CRKL ...
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The Unique Transmembrane Hairpin of Flavivirus Fusion Protein E Is Essential for Membrane Fusion
... prM protein is proteolytically cleaved by furin in the trans-Golgi network, and the C-terminal membrane-bound cleavage product of prM (M) remains associated with mature secreted virions (43, ...envelope ...
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Differences in the Postfusion Conformations of Full-Length and Truncated Class II Fusion Protein E of Tick-Borne Encephalitis Virus
... flavivirus fusion protein trimers show differences in conformation at the tips of domain ...the fusion peptide loops are widely separated and do not interact with each other as they do in the ...
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Complementation between avirulent Newcastle disease virus and a fusion protein gene expressed from a retrovirus vector: requirements for membrane fusion.
... However, the fusion protein-expressing cells, if infected with avirulent strains of NDV, would fuse with uninfected cells, suggesting that fusion requires both the fusion protein and ano[r] ...
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Insertion of the Two Cleavage Sites of the Respiratory Syncytial Virus Fusion Protein in Sendai Virus Fusion Protein Leads to Enhanced Cell-Cell Fusion and a Decreased Dependency on the HN Attachment Protein for Activity
... F protein with an intact cleavage site II, but lacking both site I and the intervening segment ( ⌬ 106–130), replicated with kinetics sim- ilar to that of the parental virus ...cell-cell fusion are ...
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Membrane fusion of Semliki Forest virus involves homotrimers of the fusion protein.
... Detailed analysis of the activation of the fusion capacity of the influenza virus HA 41 was made possible by the application of a kinetic fusion assay allowing the direct monitoring of t[r] ...
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Localization of a Region in the Fusion Protein of Avian Metapneumovirus That Modulates Cell-Cell Fusion
... attachment protein for fusion promotion (28, 47, ...F protein harbors the site(s) that determines the specificity of the interaction with homologous HN protein ...F protein of canine ...
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Mutations in the fusion peptide and heptad repeat regions of the Newcastle disease virus fusion protein block fusion.
... 7654 Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest Nonconservative mutations were introduced by site-specific mutagenesis into the fusion peptide and the adjacent hept[r] ...
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A Single Amino Acid Change in the Newcastle Disease Virus Fusion Protein Alters the Requirement for HN Protein in Fusion
... membrane fusion, processes di- rected by the viral glycoproteins. Membrane fusion mediated by most paramyxoviruses, such as Newcastle disease virus (NDV), requires two virion-associated glycoproteins, the ...
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The cytoplasmic domain of the gamete membrane fusion protein HAP2 targets the protein to the fusion site in Chlamydomonas and regulates the fusion reaction
... G is less well conserved; 3 C, not present in Plasmdium; 5 C, not present in plants; 8 C, not present in metazoans; 17 C, not present in lower metazoans (see alignment file in Liu et al., 2008). The conserved cysteines ...
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Molecular Cloning and Expression of Novel Fibroblast Growth Factor-2 Conjugated with Immunodominant Domains of Pseudomonas exotoxin
... recombinant fusion protein composed of bFGF and PE (toxin parts) that contain domain II and III in bacterial expression ...Recombinant fusion protein has considerable activity on inhibition of ...
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Physical interaction between the herpes simplex virus type 1 immediate-early regulatory proteins ICP0 and ICP4.
... Using GST-ICPO fusion protein affinity chromatography and in vitro-synthesized [35S]Met-labeled ICPO and ICP4, ICP4 was shown to interact preferentially with the fusion protein containin[r] ...
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Current status and emerging role of glutathione in food grade lactic acid bacteria
... Glutathione synthesis, transport and metabolism in Lactobacillus genus have been studied for some species but most are yet to be explored. Among lactobacilli, GshF homologs could be detected in Lb .casei, Lb. rham- ...
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Isolation and characterisation of α2-chimaerin cDNA encoding a p21rac GTPase-activating protein with an SH2 domain
... GST-fusion protein that bound phosphoamino acid-coupled agarose beads, to show the binding of the GST/Abl-SH2 domain to phosphotyrosine ...GST/Abl-SH2 fusion protein was used as a ...
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The Mycovirus CHV1 Disrupts Secretion of a Developmentally Regulated Protein in Cryphonectria parasitica
... developmental protein but also changes the location of ex- pression of a cryparin-GFP-tagged fusion ...cryparin-GFP fusion protein in infected as well as noninfected strains, fluorescence ...
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