GABAergic interneurons
Modulation of cell cycle dynamics is required to regulate the number of cerebellar GABAergic interneurons and their rhythm of maturation
... of GABAergic interneurons are preserved (Huard et ...of interneurons suggests that cyclin D2 could be required for the specification of this ...latest interneurons generated during cerebellar ...
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Compromised generation of GABAergic interneurons in the brains of Vax1 / mice
... that GABAergic interneurons are generated in the basal ganglia and migrate across the pallium/subpallium border to populate the cerebral cortex (Anderson et ...
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Multidirectional and multizonal tangential migration of GABAergic interneurons in the developing cerebral cortex
... Most GABAergic interneurons originate from the basal forebrain and migrate tangentially into the ...of interneurons takes place in both the marginal zone (MZ) and the ventricular zone (VZ) of the ...
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Inhibitory or excitatory? Optogenetic interrogation of the functional roles of GABAergic interneurons in epileptogenesis
... in GABAergic interneurons. The functional role of GABAergic interneurons is investi- gated in a 4-AP seizure model (6 mg/Kg ...inhibit GABAergic interneurons in the CA3 area ...
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GABAergic interneurons form transient layer-specific circuits in early postnatal neocortex
... GABAergic interneurons play key roles in cortical circuits, yet little is known about their early ...Nkx2-1-derived interneurons possess functional synaptic connections before emerging pyramidal cell ...
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Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments
... hippocampal GABAergic interneu- rons lose contact boutons [55], while this process is accel- erated in hAPP mice (J20 ...of GABAergic interneurons in the hippocampus of aged mutant mice compared to ...
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Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations
... of GABAergic inhibitory transmission, and its levels are reduced in cerebrospinal fluid of PD ...in GABAergic neurons derived from induced pluripotent stem cells (iPSCs) of PD ...into GABAergic ...
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MHC-I promotes apoptosis of GABAergic interneurons in the spinal dorsal horn and contributes to cancer induced bone pain
... of GABAergic interneurons was related to CD8 + T cells, we performed double immunostaining with CD8 and MHC-I as well as double immunostaining with CD8 and GABAergic ...of GABAergic ...
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Rac1 and Rac3 GTPases Control Synergistically the Development of Cortical and Hippocampal GABAergic Interneurons
... Tangential migration occurs via the cortical IZ and MZ for early-born neurons (E11.5 – E14.5) and via the cortical SVZ for those born at E14.5 – E16.5 (Anderson et al. 2001; Hernández- Miranda et al. 2010). We found no ...
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Neuregulin repellent signaling via ErbB4 restricts GABAergic interneurons to migratory paths from ganglionic eminence to cortical destinations
... for GABAergic INs, including Dlx1/2 [3], GAD67 [34], EGFR/ ErbB1 [35] and Reelin [36], we studied at postnatal day (P) 0 the cortical distribution of INs in ErbB4-/- HER4 heart mice (Figure ...of GABAergic ...
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Loss of either Rac1 or Rac3 GTPase differentially affects the behavior of mutant mice and the development of functional GABAergic networks
... (GABA)ergic interneurons are fun- damental players in modulating the activity of the neuronal cir- cuits (Batista-Brito and Fishell 2009; Gelman and Marín ...hippocampal interneurons is believed to alter ...
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Extracting non linear integrate and fire models from experimental data using dynamic I–V curves
... and GABAergic interneurons in current-clamp mode and additio- nally demonstrated that the method can be used in dynamic- clamp conductance-injection ...For interneurons, we found that the dynamic I ...
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Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1
... of GABAergic interneurons occurs at the expense of the velate astrocyte population or reflects less proliferation of the astrocytic lineage after astrocytes are formed (Supplemental Figure ...
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LIM homeodomain transcription factor dependent specification of bipotential MGE progenitors into cholinergic and GABAergic striatal interneurons
... of GABAergic and cholinergic SIN subtypes is crucial for the formation of functional neuronal circuits in the basal ganglia (Bolam et ...mature GABAergic or cholinergic SIN ...early GABAergic ...
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Transcriptional co regulation of neuronal migration and laminar identity in the neocortex
... (GABAergic) interneurons (right ...non-spiny interneurons, which are highly diverse in morphology, neurochemistry and electrophysiology, project axons within a local ...of interneurons also ...
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Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain
... Proper forebrain patterning and cell-fate specification lay the foundation for complex behaviors. These neuro- developmental events in large part depend on a series of gene expression refinements (reviewed in [1]) that ...
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Development and specification of GABAergic cortical interneurons
... telencephalon, GABAergic cortical in- terneurons face the task of migrating to their ultimate destinations within the cerebral cortex ...that GABAergic interneurons first begin a tan- gential route ...
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Mutual Control of Cholinergic and Low-Threshold Spike Interneurons in the Striatum
... of interneurons, is involved in this operation (Tepper and Bolam, ...most GABAergic interneurons and all projection neurons of the striatum are not autonomously active, two well characterized ...
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Catatonia as a Syndrome Characterized by GABAergic Interneuronal Dysfunction Mediated by NMDA Receptors
... on interneurons leads to GABA release with subsequent inhibitory stimulation ...[22,23]. GABAergic and glutamanergic stimulation must therefore be in sufficient balance in order for the brain to properly ...
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Transplant restoration of spinal cord inhibitory controls ameliorates neuropathic itch
... receptor–expressing interneurons in the superficial dorsal horn are ...these interneurons eliminates scratching provoked by a variety of pruritogens, without altering behaviors provoked by painful ...by ...
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