GABAergic neuron
Transcriptional regulatory mechanisms underlying the GABAergic neuron fate in different diencephalic prosomeres
... regulate neuron-type-specific gene batteries (Hobert, ...a neuron, positively autoregulate themselves, regulate postmitotically expressed terminal differentiation genes, including downstream transcription ...
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A New Multistep Induction Protocol for the Transdifferentiation of Bone marrow Stromal Stem Cells into GABAergic Neuron-Like Cells
... into GABAergic neuron-like cells (GNLC) after pre- induction in the presence of β-mercaptoethanol (βME) and retinoic acid (RA), followed by induction in the presence of potassium ...striatal ...
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Role for TGF-β superfamily signaling in telencephalic GABAergic neuron development
... Abstract Signaling mechanisms mediated by the Trans- forming Growth Factor-β (TGF-β) superfamily regulate a variety of developmental processes. Here we show that components of both bone morphogenetic protein/growth ...
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Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development
... Our study establishes the transcription factor Rp58 as a novel essential regulator of cerebellum development. Its loss leads to cerebellar hypoplasia, defective lamination and a defective foliation pattern. Our results ...
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Extrahypothalamic GABAergic nociceptin–expressing neurons regulate AgRP neuron activity to control feeding behavior
... BNST GABAergic neuron populations involved in the regulation of emotional states ...the GABAergic aBNST population that regulated feeding via AgRP/ NPY ...arcuate neuron populations (24, ...
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Gata2 is a tissue specific post mitotic selector gene for midbrain GABAergic neurons
... the GABAergic neurons are generated in ventral neuroepithelium and reach the cortex by dorsal tangential ...of GABAergic neurogenesis, the proneural bHLH transcription factor Ascl1 (Mash1) is expressed in ...
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PubMedCentral-PMC4824651.pdf
... which GABAergic Ube3a loss contributes to circuit imbalance? We previously found that neocortical fast-spiking interneurons receive normal excitatory synaptic drive and display appropriate intrinsic excitability ...
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Distinct developmental origins and regulatory mechanisms for GABAergic neurons associated with dopaminergic nuclei in the ventral mesodiencephalic region
... midbrain GABAergic neuron ...of GABAergic neurons with robust BrdU incorporation was analyzed in the SNpr, mRF and SC ...post-mitotic GABAergic neuron progenitors are produced first in ...
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Tangential migration and proliferation of intermediate progenitors of GABAergic neurons in the mouse telencephalon
... To confirm further that the cell-cycle phases represented cell division and not apoptosis, we examined the expression of E2f1, a suppressor of cell-cycle entry (Wang et al., 2007). E2f1 had a Present call in cell #10, ...
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Toxoplasma gondii Infections Alter GABAergic Synapses and Signaling in the Central Nervous System
... GAD67 interacts with an unknown synaptic-vesicle-associated factor (28). Currently, we do not know which of these two mech- anisms is affected by Toxoplasma. Type II ME49 Toxoplasma in- fection of cultured hippocampal ...
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Dual modulation on glial cells by tetrahydroxystilbene glucoside protects against dopamine neuronal loss
... midbrain neuron-glia cultures were treated with TSG (20–80 μM) for 30 min before LPS (10 ng/ml) ...DA neuron)-positive neuronal ...DA neuron number ...
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Sensory induced modification of two motor patterns in the crab, Cancer pagurus
... We investigated the sensory neuron AGR in the isolated stomatogastric nervous system. AGR had previously been characterized in two different crustacean species, the lobster Homarus gammarus (Combes et al., 1999; ...
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Fear vs Hope: Do Discrete Emotions Mediate Message Frame Effectiveness In Genetic Cancer Screening Appeals
... Since murine models with RTT were generated, pathophysiology of the RTT has been studied for decades. Increasing evidence reported the imbalanced neuronal excitation/inhibition may underlie the development of the ...
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Characterization of a descending pathway: activation and effects on motor patterns in the brachyuran crustacean stomatogastric nervous system
... motor neuron LG were time locked to the IV neuron bursts ...IV neuron bursts preceded those of the LG neuron argues for the hypothesis that the IV neurons contributed to the activation of the ...
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Neurons of self-defence: neuronal innervation of the exocrine defence glands in stick insects
... neck connective indicate processes of this neuron ex- tending into the suboesophageal ganglion (Fig. 8a). This neuron is referred to as prothoracic intersegmental neuron (PIN). We found the PIN in P. ...
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Development and specification of GABAergic cortical interneurons
... telencephalon, GABAergic cortical in- terneurons face the task of migrating to their ultimate destinations within the cerebral cortex ...that GABAergic interneurons first begin a tan- gential route of ...
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Timing control of single neuron spikes with optogenetic stimulation
... Izhikevich neuron model [12] (which we hereafter simply refer to as the Izhikevich ...of neuron firing patterns that can be observed is consistent with all known types of cortical neurons, as demonstrated ...
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Nasal neuron PET imaging quantifies neuron generation and degeneration
... Switching from acute injury to chronic models, our aged rodent imaging simulates human aging, and the tauopathy model simu- lates various neurodegenerative diseases. The OSN population deficits detected during aging and ...
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Axonal Transport Enables Neuron-to-Neuron Propagation of Human Coronavirus OC43
... ABSTRACT Human coronaviruses (HCoVs) are recognized respiratory pathogens for which accumulating evidence indicates that in vulnerable patients the infection can cause more severe pathologies. HCoVs are not always ...
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Mod 4 PPT.ppt
... • Dendrite – The branching extensions of a neuron that receive information and conduct impulses toward the cell body (soma).... Parts of the Neuron - Soma.[r] ...
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