Gastrulation and mesoderm formation
Decoupling of amniote gastrulation and streak formation reveals a morphogenetic unity in vertebrate mesoderm induction
... SUMMARY Mesoderm is formed during ...in mesoderm formation during early amniote evolution are not well ...for mesoderm formation in ...of gastrulation can be induced in chick and ...
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5. MESODERM FORMATION / SEGMENTATION
... patterning variations appear to be under the direction of specific combinatorial codes of Hox genes as illustrated in Fig. 5-8. Respecification can also take place. For example, if pregnant mice are treated with retinoic ...
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WNT8 and BMP2B co-regulate non-axial mesoderm patterning during zebrafish gastrulation
... vertebrate mesoderm formation, fates are established according to position in the dorsoventral (D/V) axis of the ...nascent mesoderm into axial (dorsal) and non-axial (ventral) ...axial ...
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Antagonistic role of XESR1 and XESR5 in mesoderm formation in Xenopus laevis
... prospective mesoderm prior to Xbra ...severe gastrulation defect and suppression of Xbra expression, which were completely rescued by co-injection with the active form of ...for mesoderm ...
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Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo
... To further dissect shared and/or unique roles provided by Smad2 and Smad3, we have manipulated their expression ratios in vivo. We find that Smad2;Smad3 double heterozygous animals are born at the expected Mendelian ...
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Zygotic VegT is required for Xenopus paraxial mesoderm formation and is regulated by Nodal signaling and Eomesodermin
... KNEZEVIC, V., DE SANTO, R. and MACKEM, S. (1997). Two novel chick t-box genes related to mouse brachyury are expressed in different, non-overlapping mesodermal domains during gastrulation. Development 124: ...
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Cripto is required for mesoderm and endoderm cell allocation during mouse gastrulation
... mouse gastrulation, cells in the primitive streak undergo epithelial–mesenchymal transformation and the resulting mesenchymal cells migrate out laterally to form mesoderm and definitive endoderm across the ...
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Shield formation at the onset of zebrafish gastrulation
... vertebrate gastrulation, the three germ layers, ectoderm, mesoderm and endoderm are formed, and the resulting progenitor cells are brought into the positions from which they will later contribute more ...
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FGF8 spliceforms mediate early mesoderm and posterior neural tissue formation in Xenopus
... induce mesoderm in X. laevis explants, and we show here that this mesoderm induction is due to its splicing; thus, ...of gastrulation, and a subsequent reduction in the paraxial ...
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The one-eyed pinhead gene functions in mesoderm and endoderm formation in zebrafish and interacts with no tail.
... in mesoderm and endoderm formation in zebrafish and interacts with no tail Abstract The zebrafish locus one-eyed pinhead (oep) is essential for the formation of anterior axial mesoderm, ...
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Fibroblast growth factor signalling controls successive cell behaviours during mesoderm layer formation in Drosophila
... vertebrate gastrulation, FGF signalling has been implicated in EMT, ingression and guidance of mesoderm cells away from the primitive streak (Chuai and Weijer, 2009a; Thiery et ...Drosophila mesoderm ...
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Origin and evolution of endoderm and mesoderm
... the mesoderm is also linked to the evolution of axis formation in ...and mesoderm, arise during or tightly linked to ...and mesoderm, we have to understand gastrulation and its ...
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Regional requirements for Dishevelled signaling during Xenopus gastrulation: separable effects on blastopore closure, mesendoderm internalization and archenteron formation
... of gastrulation: closure of the blastopore to bring the endoderm and mesoderm fully inside the ectoderm, and generation of the ...archenteron formation in a single ...accomplish gastrulation, ...
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Retinoid signalling is required for information transfer from mesoderm to neuroectoderm during gastrulation
... Severe changes in gene expression are seen later in the future posterior hindbrain region at the early neurula stage. This early defect is the converse of that caused by early retinoid application (Conlon and Rossant, ...
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PDGF A controls mesoderm cell orientation and radial intercalation during Xenopus gastrulation
... Unfortunately, the initial spreading of the signal could not be determined from the migratory response in explants, as irregular movements due to explant relaxation after explantation were superimposed over directed ...
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PDGF signalling controls the migration of mesoderm cells during chick gastrulation by regulating N cadherin expression
... plate mesoderm cells (Montero et ...of mesoderm cells during the early stages of gastrulation in the chick ...paraxial mesoderm cells move efficiently, a process that is likely to involve ...
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Geometry and mechanics of teleost gastrulation and the formation of primary embryonic axes
... of gastrulation and during the course of epiboly revealed that anteroposterior (AP) and dorsoventral (DV) polarity formation is connected with shaping of the blastoderm circumferential region, which ...
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Mesoderm induction by the mesoderm of Xenopus neurulae
... Int I Dev lli,,1 33 397 401 (1989) 397 Original Article Mesoderm induction by the mesoderm of Xenopus neurulae JUAN REPRESA' and JONATHAN M W SLACK' Imperial Cancer Research Fund, Developmental Biolog[.] ...
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Negative regulation of Smad2 by PIASy is required for proper Xenopus mesoderm formation
... of mesoderm markers ...including mesoderm marker induction ...of mesoderm markers by Mo-2 was completely suppressed by co- introduction of XPIASy mRNA, which does not have 5′- noncoding region ...
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Combinatorial gene regulation by Bmp and Wnt in zebrafish posterior mesoderm formation
... We find that the tbx6 promoter utilizes distinct domains to integrate the signaling inputs from each pathway, including multiple Tcf/LEF sites and a novel Bmp-response element. Surprisingly, we found that overexpression ...
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