GATA factors
GATA factors efficiently direct cardiac fate from embryonic stem cells
... the GATA factors, under serum-free conditions, has capacity to induce cardiogenesis, but with ...the GATA genes themselves, plotted as log differences compared with the uninduced controls for ...
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Hand is a direct target of Tinman and GATA factors during Drosophila cardiogenesis and hematopoiesis
... and GATA consensus-binding sites in the HCH enhancer To further assess the potential importance of Tinman and GATA factors for activation of the Hand enhancer in vivo, we generated transgenic flies ...
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Essential role of Gata transcription factors in sympathetic neuron development
... liver, Gata transcription factors mediate the effects of Bmps (Maeno et ...that Gata factors maintain Bmp expression during cardiac precursor maturation (Peterkin et ...2003). Gata ...
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BMP mediated induction of GATA4/5/6 blocks somitic responsiveness to SHH
... exclusive pattern in vivo (Fig. 1B-H), and NKX3.2 is a transcriptional repressor (Murtaugh et al., 2001), we examined whether NKX3.2 might conversely repress the expression of GATA4/5/6. Chicken PSM explants were ...
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The essential role of GATA transcription factors in adult murine prostate
... transcription factors are essential in mammalian cell lineage determination and have a critical role in cancer ...six GATA members, GATA2 and GATA3 are ...both GATA factors predominantly ...
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Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development
... A GATA- and ISL1-dependent transcriptional cascade in the anterior heart field contrasts with the hierarchy present in the primary heart field and in the Drosophila ...the GATA transcription factor gene, ...
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Gata4 expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element
... via GATA and other transcription factor families. GATA transcription factors also appear to activate Bmp4 expression, further supporting the notion of a reinforcing transcriptional network (Nemer and ...
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The function and regulation of the GATA factor ELT 2 in the C elegans endoderm
... small GATA- type transcription factors, END-1 and END-3, are transcriptionally activated only in the E blastomere (Maduro et ...the GATA factor ELT-7, at the 2E cell stage (Nair et ...the GATA ...
9
Combinatorial regulation of tissue specification by GATA and FOG factors
... six GATA proteins and two FOG proteins (Evans et ...six GATA factors contain both the N and C zinc finger domains and all are capable of interacting with FOG proteins (Tevosian et ...between ...
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Cell fate control by pioneer transcription factors
... and GATA of a liver-specific enhancer in endoderm chromatin prior to the specification of liver cells, and the fact that at least FoxA could target nucleosomal DNA, suggested that these proteins functioned as ...
5
Rapamycin Treatment Results in GATA Factor-Independent Hyperphosphorylation of the Proline Utilization Pathway Activator in Saccharomyces cerevisiae
... In this report, we demonstrate that rapamycin treatment results in hyperphosphorylation of the activator of the proline utilization pathway, Put3p. To date, this is only the second report of rapamycin-induced ...
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GATA transcription factors in development and disease
... GATA4/5/6 are central regulators of cardiac development (Clowes et al., 2014; Peterkin et al., 2005). Among them, GATA4 has the earliest unique function in the heart, as its inactivation in the mouse leads to embryonic ...
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Members of the GATA Family of Transcription Factors Bind to the U3 Region of Cas-Br-E and Graffi Retroviruses and Transactivate Their Expression
... cases: GATA-1 cooperates with Ets to activate the platelet glycoprotein Ib and IIb (GpIb and GpIIb) promoters (31, 41) and also with SP1 and EKLF (29); GATA-2 cooperates with the AP-1 complex to activate ...
10
GATA transcription factors integrate Wnt signalling during heart development
... of GATA transcription factors in overexpression experiments (Gove et ...with GATA factors during early cardiogenesis (Ku and Melton, 1993) (see ...of GATA transcription factors ...
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Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa
... neither GATA-4 nor GATA-6 in these cells (this ...of GATA factors in neuroendo- crine cell hyperplasia raises the question of whether they contribute to the progression of neuroendocrine neo- ...
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Regulation of Nitrogen Metabolism by GATA Zinc Finger Transcription Factors in Yarrowia lipolytica
... nium, tryptophan, and urea, as well as a complex nitrogen source consisting of peptone and yeast extract (Fig. 4A). Deletion of gzf2 resulted in a severe growth defect when grown with ammonium, tryptophan, or urea as the ...
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Expression of Th1 and Th2 Cytokine and Associated Transcription Factors in Peripheral Blood Mononuclear Cells and Correlation with Disease Severity
... Methods: Thirty plaque-type psoriasis patients with Psoriasis Area and Severity Index (PASI) scores greater than 10 were recruited; these were 15 non-micronutrients taking- (NMT) patients treated with MTX daily (0.2-0.3 ...
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Hemoglobin Switching in Humans Is Accompanied by Changes in the Ratio of the Transcription Factors, GATA-1 and SP1
... clear extracts of K562 cells as a positive control; Lanes 2 and 13 (designated c), cold competition-binding in the presence of 100-fold molar excess of unlabeled oligonucleotide; Lanes 3[r] ...
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TO STUDY RETENTION TIME OF ANUVASANA BASTI BETWEEN ANCIENT AND RECENT PRACTICE OF KAAL BASTI IN MANAGEMENT OF PAKWASHAYA GATA VATA
... These factor associated with ushna bring about sanchay and this ushnatva is more predominant in the region of Mumbai, as more of humidity brings natural sweating of the body. People did not follow a course of live ...
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Functions of atoh8 and Mekk3 in Cardiovascular Development
... The transcription factor ATOH8 and the kinase MEKK3 are evolutionary conserved proteins with known expression within the cardiovascular system. However, the roles of these proteins in the developing heart are undefined. ...
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