γδ T cells
Celastrol increases osteosarcoma cell lysis by γδ T cells through up-regulation of death receptors
... OS cells or OS cells pretreated with celastrol induces an enhanced IFNγ production and CD69 expression in γδ T cells in ...between γδ T cells and OS cells ...
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Successful adoptive transfer and in vivo expansion of haploidentical γδ T cells
... (NK) cells (A), γδ T cells (B), and αβ T cells (C) per ...TCR γδ , CD56, and donor-specific HLA antibodies by four-colour FACS ...haploidentical γδ T ...
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A variant of SCID with specific immune responses and predominance of γδ T cells
... B cells, a reduced number of T cells, and a nor- mal level of NK cells, likely reflecting the consequences of impaired V(D)J recombination for lymphocyte development (Table ...of γδ ...
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Gamma delta (γδ) T cells: friend or foe in cancer development?
... αβ T cells and its ligand PD-L1 on γδ T cells restrains αβ T cell activa- ...Vδ2 T cell cytotoxicity, whereas the other seven (CLEC2D, NRP2, SELL, PKD2, KCNK12, ITGA6 and ...
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γδ T cells and NK cells – Distinct Pathogenic Roles as Innate Like Immune Cells in CNS Autoimmunity
... Th17 cells, including expression of RORγt, IL-1R1, IL-23R, and CCR6 ...Although γδ T cells do express a unique T cell receptor (TCR), engagement of this TCR with MHC-antigen complexes ...
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Development of interleukin-17-producing Vγ2 γδ T cells is reduced by ICOS signaling in the thymus
... killer T (NKT) cells and the recently discovered natural Th17 (nTh17) cells [26, ...Treg cells [28]. ICOS is expressed by γδ T cells [29] already in the thymus, but little ...
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Immune synapses between mast cells and γδ T cells limit viral infection
... and γδ T cells in ...activate T cells in vitro, we questioned whether this occurs in ...and γδ T cells. As MCs are tissue resident and γδ T ...
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Functional studies on human γδ T cells and their interactions with dendritic cells and B cells
... γδ T cells have attracted interest as immunotherapeutic agents owing to their ability to respond rapidly when faced with a wide array of pathogens or transformed cells, without the requirement ...
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Circulating γδ T cells in young/adult and old patients with cutaneous primary melanoma
... of γδ T ...viable cells were determined by trypan blue exclusion and used for FACS ...of γδ T cells was followed by cytometric analysis through dou- ble staining of stimulated ...
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Age-associated alterations in γδ T-cells are present predominantly in individuals infected with Cytomegalovirus
... of γδ T-cells with ...late-differentiated T-cells within the V δ 2 - population, but only in CMV-seropositive ...early-differentiated cells within the V δ 2 - ...- T-cell ...
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Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice
... of T cells, macrophages, dendritic cells, and ...Th17 cells in disease ...Th17 cells were not the primary source of these pathogenic ...of γδ T cells and RORγt + ...
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Clonally expanded γδ T cells protect against Staphylococcus aureus skin reinfection
... TRGV5/V6 γδ T cells in the skin-draining ...pathogen-induced T cell expansion. Although it is unclear whether the γδ T cell TCR reactivity was against a yet-to- be-described ...
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Implication of γδ T cells in the human immune response to cytomegalovirus
... individuals, γδ T cells account for less than 6% of total peripheral T lymphocytes and mainly express T-cell receptor (TCR) Vδ2-Vγ9 ...of γδ T cells in the ...
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Long-term use of interferon-β in multiple sclerosis increases Vδ1−Vδ2−Vγ9− γδ T cells that are associated with a better outcome
... addition, γδ T cells are also assumed to be involved in the pathogenesis of various inflammatory diseases [2], although γδ T cells comprise < 5% of lymphocytes in the ...
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γδ T Cells and Their Potential for Immunotherapy
... γδ T cells can recognize MHC molecules such as group 1(CD1a, b, c) and group 2 (CD1d) CD1 mole- cules [43, ...human γδ T cells, and do not need Ag processing ...(CMV)–infected ...
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Human γδ T Cells Augment Antigen Presentation in Listeria Monocytogenes Infection
... Circulating γδ T cells in healthy individuals rapidly respond to bacterial and viral ...that γδ T cells are activated and expanded by Listeria monocytogenes ...of γδ ...
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γδ T cells: an immunotherapeutic approach for HIV cure strategies
... Vδ2 T cells were able to expand up to 120-fold in response to PAM/IL-2 ex vivo and reduce viral replication up to 80% in autologous coculture ...that γδ T cells possess antiviral ...
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Expression of regulatory receptors on γδ T Cells and their cytokine production in Behcet's disease
... T cells have been shown to regulate other cells by secretion of cytokines and chemokines, such as CCL4 and CCL5 [6,25], in response to components of bacterial cell walls, supporting a role for these ...
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γδ T Cells Play a Protective Role in Chikungunya Virus-Induced Disease
... digestion, cells were passed through a 40- m cell strainer and washed in wash buffer, and total viable cells were determined by trypan blue ...exclusion. Cells were stained in ...
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Association of γδ T Cells with Disease Severity and Mortality in Septic Patients
... ␥␦ T cells and natural killer T cells after viral infection in rhesus macaques ...these T cell subsets in humans, and even less in septic ...NKT␣ cells that recognize ...
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