gene clusters
Comparative Analyses of Gene Clusters and Ks-alpha Genes Involved in the Biosynthesis of Chromomycin A3 and Mithramycin
... biosynthetic gene clusters of two aureolic acids ...The gene sequence of KSα was used for preliminary classification of bacterial strains on the basis of their genetic abilities to produce different ...
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Distinct Host Species Correlate with Anaplasma phagocytophilum ankA Gene Clusters
... rRNA gene was used, but it might be not informative enough to delineate distinct genotypes of ...rRNA gene sequences was not meaningful, we showed that distinct host species correlate with ...
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Prediction of Human Disease-Related Gene Clusters by Clustering Analysis
... dense clusters as the candidates of disease-related clusters, and then a log likelihood model that integrates multiple biological evidences was proposed to score these dense ...disease-related ...
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Gene clusters of Hafnia alvei strain FB1 important in survival and pathogenesis: a draft genome perspective
... A sequence-based comparison between the two H. alvei genomes and FB1 was performed, and the result was pre- sented as a colour-labelled circular map in Figure 3. It was shown that ATCC 51873 displayed a higher level of ...
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A genetical metabolomics approach for bioprospecting plant biosynthetic gene clusters
... predicted gene clusters showed only overlap with mQTLs of metabolites that have not been annotated yet, showing a clear potential for discovery of novel enzymes that can be tested through synthetic biology ...
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The evolution and maintenance of Hox gene clusters in vertebrates and the teleost specific genome duplication
... Hox clusters (Garcia- Fernandez and Holland, ...Evx gene are aligned within 700 kb in a single genomic contig (Cameron et ...the gene order and orientation of transcription are quite scrambled in ...
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SMCHD1 regulates a limited set of gene clusters on autosomal chromosomes
... somal gene clusters, aside from its repressive role at the D4Z4 ...autosomal gene clusters, in- sinuating a role for methylation maintenance at these loci and proving that a heterozygous ...
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Functional Operons in Secondary Metabolic Gene Clusters in Glarea lozoyensis (Fungi, Ascomycota, Leotiomycetes)
... lozoyensis gene loci transcribed as ...possess gene or- ganization patterns similar to that of the glpks3-glnrps7 locus ...upstream gene or tran- scription initiation site for the downstream ...
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Clust: automatic extraction of optimal co expressed gene clusters from gene expression data
... to gene expression data generates clusters that include substantial numbers of unreliably assigned genes, ...from gene expression data. Clust is designed to extract co-expressed clusters of ...
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Evolution of homeobox gene clusters in animals : the Giga cluster and primary versus secondary clustering
... Hox gene cluster has been a major focus in evolutionary developmental ...genomic clusters in which the order of the genes along the chromosome corresponds to the order of their activity along the embryo, or ...
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ATNT: an enhanced system for expression of polycistronic secondary metabolite gene clusters in Aspergillus niger
... biosynthetic gene clusters. Heterologous gene expression generally aims for high product yields to elucidate the structure of the metabolite and to analyse its biological ...biosynthetic gene ...
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Analysis of Homologous Gene Clusters in Caenorhabditis elegans Reveals Striking Regional Cluster Domains
... Gene clusters contain unusual genes: By various mea- sures, the gene families identified by the clustering al- gorithm are ...nematode-specific gene prod- ucts. In contrast to clustered ...
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Gene Clusters for Insecticidal Loline Alkaloids in the Grass-Endophytic Fungus Neotyphodium uncinatum
... Loline alkaloids are produced by mutualistic fungi symbiotic with grasses, and they protect the host plants from insects. Here we identify in the fungal symbiont, Neotyphodium uncinatum, two homologous gene ...
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Degeneration of aflatoxin gene clusters in Aspergillus flavus from Africa and North America
... Aflatoxin gene cluster assembly and comparative analysis To ensure the quality of the reads, the raw reads obtained from AGI were quality trimmed and cleaned using cuta- dapt ...aflatoxin gene cluster from ...
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Rational engineering of Streptomyces albus J1074 for the overexpression of secondary metabolite gene clusters
... diverse gene clusters and proved to be a preferred host for expression of metagenomic DNA clones encoding secondary metabolites ...its gene expression capabilities by targeted genetic ...native ...
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MIBiG 2.0: a repository for biosynthetic gene clusters of known function
... Plants, microbes and fungi produce a large variety of spe- cialized metabolites that are often uniquely found in one or a few species. From the dawn of civilization, humans have tapped into this treasure trove for ...
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Validation of hierarchical gene clusters using repeated measurements
... few clusters had stability more than ...the gene clusters, therefore, the stability of the cluster, which could not divide into, stable sub-clusters were chosen as the stability for comparison ...
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The gentle art of gene arrangement: the meaning of gene clusters
... in gene arrangement between individ- uals; the KIR loci must have evolved recently as they are restricted to ...immune-gene clusters that, like the MHC, could be subject to inheritance as functional ...
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The rise and fall of Hox gene clusters
... Hox gene clusters, with all genes in the same transcriptional orientation, spanning ~100 ...These clusters are very rich in conserved non-coding DNA sequences, they are mostly devoid of any ...
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IMG ABC: A Knowledge Base To Fuel Discovery of Biosynthetic Gene Clusters and Novel Secondary Metabolites
... biosynthetic gene clusters within the Integrated Microbial Genomes (IMG) system, which is aimed at harnessing the power of “big” genomic data for discovering small ...biosynthetic gene clus- ters ...
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