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Gene expression signature

Longitudinal Transcriptome Analysis Reveals a Sustained Differential Gene Expression Signature in Patients Treated for Acute Lyme Disease

Longitudinal Transcriptome Analysis Reveals a Sustained Differential Gene Expression Signature in Patients Treated for Acute Lyme Disease

... differential gene expression signature of Lyme disease following the acute phase of infection persisted for at least 3 weeks and had fewer than 44% differentially expressed genes (DEGs) in common ...

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A Sputum 6 Gene Expression Signature Predicts Inflammatory Phenotypes and Future Exacerbations of COPD

<p>A Sputum 6 Gene Expression Signature Predicts Inflammatory Phenotypes and Future Exacerbations of COPD</p>

... PCR-based gene expression signa- ture of 6 biomarkers that can discriminate in fl ammatory phenotypes, 7,8 predict corticosteroid responsiveness, 7,9 and identify exacerbation prone ...6 gene ...

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Prognostic stratification improvement by integrating ID1/ID3/IGJ gene expression signature and immunophenotypic profile in adult patients with B-ALL

Prognostic stratification improvement by integrating ID1/ID3/IGJ gene expression signature and immunophenotypic profile in adult patients with B-ALL

... by gene expression profiling in adult B- ALL, we analyzed 43 primary leukemia samples using gene expression microarrays and confirmed the most relevant findings with RT-PCR ...different ...

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A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK

A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK

... on gene expression in several cell lines [13]. By querying a gene expression signature of disease patho- genesis against the CMap dataset, one can find com- pounds that elicit a pattern ...

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Identification and validation of a 44-gene expression signature for the classification of renal cell carcinomas

Identification and validation of a 44-gene expression signature for the classification of renal cell carcinomas

... individual gene analyses, and they remain difficult to use in clinical ...individual gene expression and often used to confirm the findings of microarray and RNA-sequencing ...the expression ...

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Original Article Gene expression signature associated with metastasis of stomach adenocarcinoma

Original Article Gene expression signature associated with metastasis of stomach adenocarcinoma

... of gene expression signature involved in metastasis is highly ...mRNA expression profiles for metastatic and non-metastatic STAD samples, ...specific gene expression patterns and ...

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Obesity and prostate cancer: gene expression signature of human periprostatic adipose tissue

Obesity and prostate cancer: gene expression signature of human periprostatic adipose tissue

... tissue gene expression signature of men with prostate cancer was determined, in order to deter- mine if functional alterations are associated with prostate cancer besides the previously reported PP ...

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A robust prognostic gene expression signature for early stage lung adenocarcinoma

A robust prognostic gene expression signature for early stage lung adenocarcinoma

... nostic gene expression signature for early stage lung ...The signature was validated in an inde- pendent cohort, however, with 95 patients in the regres- sion, of which many left the study or ...

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Cia5dregulates a new fibroblast like synoviocyte invasion associated gene expression signature

Cia5dregulates a new fibroblast like synoviocyte invasion associated gene expression signature

... Five of the differentially expressed genes were located within the Cia5d interval, and this number was greater than expected by chance. Three of these were upregulated in DA.F344(Cia5d) FLS (Ncor1, Trim41, and Gtlf3b) ...

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Gene-expression signature functional annotation of breast cancer tumours in function of age

Gene-expression signature functional annotation of breast cancer tumours in function of age

... on gene-expression profile homologies of an intrinsic gene list that included 427 unique genes: basal-like, HER2-E, luminal A, luminal B, and normal breast-like [1, ...numerous ...

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A common gene expression signature in Huntington’s disease patient brain regions

A common gene expression signature in Huntington’s disease patient brain regions

... chaperone gene containing module that was negatively correlated with HD (FC4neg5, Table 2) highlighting the complex regulation of the proteostasis network and its potential suppression through other mechanism ...

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Prognostic value of an autophagy-related gene expression signature for endometrial cancer patients

Prognostic value of an autophagy-related gene expression signature for endometrial cancer patients

... ARGs expression profiles were downloaded from TCGA and normalized by [log2(data + ...the gene expression profile of the train set, ARGs were submitted to univar- iate, LASSO Cox regression and ...

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Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis

Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis

... is dependent on TGFβ signaling, was reported [38]. This list of genes was enriched in the down-regulated mod- ules of both primed and acutely activated microglia. Two genes that are particularly interesting in this re- ...

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A gene expression signature identifying transient DNMT1 depletion as a causal factor of cancer-germline gene activation in melanoma

A gene expression signature identifying transient DNMT1 depletion as a causal factor of cancer-germline gene activation in melanoma

... CG gene hypomethylation in tumors relies on a general defect in DNA methylation maintenance activities, and several mechanisms that might cause such type of epigenetic im- balance have been ...DNMT1 ...

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Gene expression signature in mouse thyroid tissue after 131I and 211At exposure

Gene expression signature in mouse thyroid tissue after 131I and 211At exposure

... Additionally, gene products of several other recurrently regulated genes are also calcium- related according to literature reports, but not associ- ated with calcium signalling in the IPA canonical path- way ...

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Gene Expression Signature to Predict Prognosis and Adjuvant Chemosensitivity of Colorectal Cancer Patients

<p>Gene Expression Signature to Predict Prognosis and Adjuvant Chemosensitivity of Colorectal Cancer Patients</p>

... However, similar to other expression-based classi fi ers, there is a limitation in clinical use of different qualitative- and quantitative-based methods. Although all the data used in this study were normalized by ...

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CRC-113 gene expression signature for predicting prognosis in patients with colorectal cancer

CRC-113 gene expression signature for predicting prognosis in patients with colorectal cancer

... CRC-113 gene signature have critical roles in cell proliferation, angiogenesis, migration, invasion and metastasis of ...CRC-113 gene signature includes a number of hypoxia and ...

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Gene expression profiling predicts a three-gene expression signature of endometrial adenocarcinoma in a rat model

Gene expression profiling predicts a three-gene expression signature of endometrial adenocarcinoma in a rat model

... The quality control of the GenePix Extraction results was performed using methods available from Bioconductor packages (marray, limma, arrayQuality) in the statistical software package R. Intensities of negative and ...

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Gene expression signature of atypical breast hyperplasia and regulation by SFRP1

Gene expression signature of atypical breast hyperplasia and regulation by SFRP1

... and gene expression patterns were used to define signatures that distinguish AH lesions from HNB ...on gene expression patterns suggesting that these premalignant lesions share under- lying ...

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A 19-Gene expression signature as a predictor of survival in colorectal cancer

A 19-Gene expression signature as a predictor of survival in colorectal cancer

... The gene expression data from Coloprint was not made publicly available hence the evaluation of the classifier cannot be performed ...113 gene signatures from a published gene ...

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