Gene quantification and gene copy number analysis
Gene Copy-Number Alterations: A Cost-Benefit Analysis
... of gene copy-number changes in developing ...the gene products amplified/deleted in partic- ular ...a gene encoding the GABA A receptor subunit, has been associated with autism spectrum ...
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Analysis of gene copy number changes in tumor phylogenetics
... the number of single gene duplication and loss events between them, a minimum weight tree, includ- ing Steiner nodes if needed, explains the n observed cell count patterns of d probes with minimum total ...
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Phylogenetic Reconstruction Analysis on Gene Order and Copy Number Variation
... cancer copy number ...cells. Copy number profiles provide a tool to better understand how the genomic structure alteration occurs from the ...phylogenetic analysis of copy ...
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Copy number variants, diseases and gene expression
... 2009 Copy number variation (CNV) has recently gained considerable interest as a source of genetic variation likely to play a role in phenotypic diversity and ...in copy number among seemingly ...
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Characterization of single gene copy number variants in schizophrenia
... this gene set and the relative size, we also performed a larger validation of deletions using a higher throughput method that again confirmed 4 qPCR validated single-gene deletions in cases as well as ...
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Expression of the immunoglobulin VH gene 51p1 is proportional to its germline gene copy number
... H gene that is frequently ex- pressed in B cell chronic lymphocytic leukemia and early in B cell ...51p1 gene locus is highly polymorphic, consisting of 13 alleles that can be classified as being either ...
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Importance of rare gene copy number alterations for personalized tumor characterization and survival analysis
... of gene expression levels for cancer cell lines and tumor patients. Gene-specific correlations between predicted and originally measured gene expression levels of individual genes comparing CCTN ...
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Gefitinib and EGFR Gene Copy Number Aberrations in Esophageal Cancer.
... mutation analysis may not be representative of the intention-to-treat population from the original ...and analysis were hypothesis driven, performed to diagnostic standard in a reference laboratory with ...
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Plasmodium copy number variation scan: gene copy numbers evaluation in haploid genomes
... by gene amplification events. Thus copy number variation (CNV) is a major mechanism enabling parasite genomes to adapt to new environmental ...
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Plasmodium copy number variation scan: gene copy numbers evaluation in haploid genomes.
... by gene amplification events. Thus copy number variation (CNV) is a major mechanism enabling parasite genomes to adapt to new environmental ...
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Consequences of growth media, gene copy number, and regulatory mutations on the expression of the PRB1 gene of Saccharomyces cerevisiae.
... Most likely the SNF2 and SNFS gene products affect protease B expression at another level as well, because protease B activity in the snf2 and snf5 mutants ac- cumul[r] ...
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The soybean sucrose binding protein gene family: genomic organization, gene copy number and tissuespeci c
... SBP gene family from soybean is represented by at least two non-allelic genes corresponding to the previously isolated GmSPB1 and GmSBP2/S64 ...GmSPB2 gene structure is similar to that of other members of ...
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Low copy number of the FCGR3B gene and rheumatoid arthritis: a case control study and meta analysis
... Copy number, linkage disequilibrium and disease association in the FCGR ...3B gene copy number with rheumatoid arthritis in Caucasian ...
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Integrated analysis of copy number alterations and gene expression: a bivariate assessment of equally directed abnormalities
... 2 METHODS 2.1 Segmentation of CN data CN and GE in general are measured on different platforms, i.e. possibly not at the same locations and based on DNA sections of different lengths. As a consequence of the differences ...
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Systematic quantification of gene interactions by phenotypic array analysis
... between gene deletion and induced ...as gene clusters with shared strength and selectivity of interaction ...quantitative analysis of gene interaction networks that buffer cell ...
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Chromosome 9p21 gene copy number and prognostic significance of p16 in ESFT
... ARF gene status, mRNA and protein expression in cancer emphasises the importance of investigating these and interacting cell-cycle regulatory genes in the same clinical samples, according to standardised methods, ...
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Human amylase gene copy number variation as a determinant of metabolic state
... AMY1 copy had an effect on serum amylase that was almost three times greater in obese women than in obese men, suggesting that AMY1 copies may actually be less functional in obese ...AMY1 copy number ...
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The Neutral Coalescent Process for Recent Gene Duplications and Copy-Number Variants
... duplicate gene has fixed recently in the population, diversity in the new gene is expected to be significantly reduced, and an excess of rare alleles is also ...of gene conversion between duplicates, ...
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Correlation of EGFR expression, gene copy number and clinicopathological status in NSCLC
... FISH analysis in combination with IHC independent of the choice of antibody Dako PharmDx, 31G7 and ...FISH analysis to facilitate more patients for EGFR specific treatments concerning their EGFR expression ...
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Dietary Variation and Evolution of Gene Copy Number among Dog Breeds
... AMY2B copy number may have been subject to positive selection in multiple breeds that consumed starch-rich ...starch. Analysis of global trends in AMY2B CNV in a variety of breeds also showed that ...
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