genetic ancestry
Health and genetic ancestry testing: time to bridge the gap
... between genetic ancestry and health accentuates the gaps that currently exist in policy and in the available guidance for consumers because little attention has been given to the health implications of ...
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Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort
... European genetic ances- try, while the second PC denotes East Asian and/or Native American genetic ...African ancestry only were also subject to onomastics to determine likely countries of ...unique ...
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Effect of genetic ancestry to the risk of susceptibility to gastric cancer in a mixed population of the Brazilian Amazon
... Amerindian genetic ancestry and INDEL poly‑ morphisms associated with susceptibility of childhood B‑Cell Leukemia in an admixed population from the Brazilian ...
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Robust Estimation of Local Genetic Ancestry in Admixed Populations Using a Nonparametric Bayesian Approach
... local genetic ancestry of individuals in an admixed ...local ancestry estimation ignore the latent genetic relatedness between ancestral populations and treat them as ...spurious ...
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Softwares and methods for estimating genetic ancestry in human populations
... Genetic ancestry can be divided into “local” and “global” estimates ...each ancestry (summing to 1) can be assigned to each in- ...estimating genetic ancestry can also be divided into ...
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Multiplex genotyping system for efficient inference of matrilineal genetic ancestry with continental resolution
... can ancestry [36]. Therefore, for any bio-geographic ancestry prediction purposes, mtDNA evidence should be interpreted in the context of the relevant local demo- graphic ...s genetic ...
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Towards a phenome-wide catalog of human clinical traits impacted by genetic ancestry
... local ancestry for three specific regions as- sociated with three specific traits including QRS ...local ancestry estimates for the SCN10A fine-mapped ...similar genetic effect size and direction ...
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Association of genetic ancestry with colorectal tumor location in Puerto Rican Latinos
... of ancestry proportions between cases and ...the ancestry pro- portions by participant status is shown in ...considering genetic ancestry as dichotomous variables, we used a cut-off of the ...
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Use of local genetic ancestry to assess TOMM40-523′ and risk for Alzheimer disease
... local genetic ancestry genome-wide single nucleotide polymorphism (SNP) geno- typing was performed using 3 different platforms: Expanded Multi-Ethnic Genotyping Array, Illumina 1Mduo (v3), and the Global ...
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Breast cancer risk and genetic ancestry: a case–control study in Uruguay
... mitochondrial ancestry estimates with breast cancer ...European ancestry and, con- currently, a protective effect of Native American ances- ...the ancestry effects we uncovered is consistent with ...
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Genes reveal traces of common recent demographic history for most of the Uralic speaking populations
... Previous genetic studies have shown that demographic histories of Uralic-speaking populations inferred from ma- ternally inherited mitochondrial (mtDNA) and paternally inherited Y chromosomes (chrY) are ...common ...
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Genomic ancestry as a predictor of haemodynamic profile in heart failure
... of ancestry were normally distributed, except for the variable O/C ...log-transformed. Genetic ancestry variables were used as continuous vari- ...African ancestry while the second model used ...
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Detecting individual ancestry in the human genome
... global ancestry and population ancestry methods (for example, [69]), or using the output from these algorithms as summary sta- tistics [40], can improve the identification of population ...
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Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores
... European genetic ancestry calculated using fastNGSadmix [11] using 1KPG as the reference panel, (2) self-identified as “Caucasian,” and (3) did not have pathogenic or likely pathogenic variants in the ...
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Family tree and ancestry inference: is there a need for a ‘generational’ consent?
... provide ancestry services based mainly on the analysis of a DNA sample provided by the ...African Ancestry asks clients to confirm that they have the right to submit samples from others: “By submitting a ...
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No evidence for assortative mating within a willow warbler migratory divide
... neutral genetic markers are homogeneous across their ...and genetic markers of two chromosomal regions previously identified show steep clines across the ...morphology, genetic markers and feather ...
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Book Review
... the genetic ancestry test (the rather problematic method of using ancestry information contained in DNA to suggest physical characteristics of the assailant, for example, skin ...
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Genetic Influences on Evening Preference Overlap with Those for Bipolar Disorder in a Sample of Mexican Americans and American Indians
... Willour et al. (2012) was of European ancestry. It is likely that neither the signal identified in our study nor the sig- nal identified by Willour and colleagues is the causal sig- nal and, furthermore, that LD ...
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‘Health and ancestry start here’: Race and prosumption in direct-to-consumer genetic testing services
... the genetic makeup of African Americans and their likelihood to develop hypertension, heart failure, or type 2 ...purely genetic relationship between racial group and disease predisposition is misleading at ...
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Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease
... European ancestry con- fer risk of RA in African-Americans, whereas discordant genetic loci appear to be the minority ...European genetic admixture [9], and this is likely to be the case for several ...
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