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genetic association

Genetic susceptibility to allergic bronchopulmonary aspergillosis in asthma: a genetic association study

Genetic susceptibility to allergic bronchopulmonary aspergillosis in asthma: a genetic association study

... and genetic susceptibility to ABPA, we conducted a much larger genetic association study, involving almost 100 ABPA patients and using atopic asthmatic patients as controls, as well as a second ...

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3D Facial Morphological Analysis for Genetic Association

3D Facial Morphological Analysis for Genetic Association

... the genetic association of human facial morphological variation recently becomes a more and more active research field, which aims to quantitatively analyze the possible relation measure between the gene ...

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Evidence for genetic association of RORB with bipolar disorder

Evidence for genetic association of RORB with bipolar disorder

... Here we report association studies for RORA and RORB in a pediatric bipolar disorder cohort. Bipolar disorder in children and adolescents is characterized by more rapid cycling and switching compared to adult ...

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Reporting and evaluating genetic association studies

Reporting and evaluating genetic association studies

... All genetic association studies must address the issue of multiple testing and comparisons [1,3,9]. While it is widely considered that the Bonferroni correction is too conservative a correction for most ...

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Genetic model misspecification in genetic association studies

Genetic model misspecification in genetic association studies

... the genetic determinant of a trait is generally not known with certainty a ...in genetic association studies, a dominant model might be erroneously modelled as additive, an error inves- tigated ...

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Genetic association study of PDLIM5 and HTR2A variants in Malaysian subjects diagnosed with bipolar disorder; a genetic modelling approach

Genetic association study of PDLIM5 and HTR2A variants in Malaysian subjects diagnosed with bipolar disorder; a genetic modelling approach

... by genetic association studies that relate several polymorphisms on PDLIM5 with mental ...significant association found in schizophrenia [21], major depression [22] and BPD ...

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Addressing Sources of Bias in Genetic Association Studies

Addressing Sources of Bias in Genetic Association Studies

... concordant association testing results with the CAD case-control samples from the WTCCC, indicating there is a lower probability of making Type I Errors with such a batch ...in association results due to ...

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Pedigree association: assigning individual weights to pedigree members for genetic association analysis

Pedigree association: assigning individual weights to pedigree members for genetic association analysis

... Objective: Methods exist to appropriately perform association analyses in pedigrees. However, for genome-wide association analysis, these methods are computationally impractical. It is therefore important ...

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Statistical Methods in Genetic Association Studies

Statistical Methods in Genetic Association Studies

... about 30 SNP loci are enough to get a mean accuracy of 90% correct assignment. When the number of SNP loci used is more than 100, YRI gets 100% correct assign- ment, CEU and CVJ also get nearly perfect assignment ...

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Association between common variation at the FTO locus and changes in Body Mass Index from infancy to late childhood : the complex nature of genetic association through growth and development

Association between common variation at the FTO locus and changes in Body Mass Index from infancy to late childhood : the complex nature of genetic association through growth and development

... FTO/BMI association varies by age ...the association between common variation at FTO and BMI appears to be reduced in magnitude, with smaller studies being unable to detect association ...this ...

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Statistical Methods in Genetic Association Studies and a Genetic Risk Score for Predictive Modeling of Disease Risk: from Gene Discovery to Translation.

Statistical Methods in Genetic Association Studies and a Genetic Risk Score for Predictive Modeling of Disease Risk: from Gene Discovery to Translation.

... and genetic variants have arisen, many variants are associated/correlated with each ...common genetic variants relate to one another [Frazer, et ...the genetic contribution to common ...of ...

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Sex chromosomes and genetic association studies

Sex chromosomes and genetic association studies

... For loci on the X chromosome, the methods discussed above can readily be adapted by stratification by sib pair. However, a complication is presented by unlike-sex sib pairs. The conditional argument requires one to argue ...

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The Genetic Overlap Between Hair and Eye Color

The Genetic Overlap Between Hair and Eye Color

... 56-464-14192, Genetic Association Infor- mation Network (GAIN) of the Foundation for the Na- tional Institutes of Health, Rutgers University Cell and DNA Repository (NIMH U24 MH068457-06), the Avera Insti- ...

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Body Mass Index and Depressive Symptoms: Testing for Adverse and Protective Associations in Two Twin Cohort Studies

Body Mass Index and Depressive Symptoms: Testing for Adverse and Protective Associations in Two Twin Cohort Studies

... shared genetic background of body weight and de- pressive ...several genetic variants related to depression are also related to inflammation (Raison & Miller, ...31-SNP genetic risk marker for ...

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Association between TNF, IL1B, IL6, IL10 and IFNG polymorphisms and recurrent miscarriage: a case control study

Association between TNF, IL1B, IL6, IL10 and IFNG polymorphisms and recurrent miscarriage: a case control study

... the association of eight selected cytokine gene polymorphisms with risk of recurrent miscarriage among Chinese ...their association with the risk of recurrent miscarriage in a number of populations, and ...

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Comparison of multilevel modeling and the family based association test for identifying genetic variants associated with systolic and diastolic blood pressure using Genetic Analysis Workshop 18 simulated data

Comparison of multilevel modeling and the family based association test for identifying genetic variants associated with systolic and diastolic blood pressure using Genetic Analysis Workshop 18 simulated data

... family-based genetic association studies ...family-based genetic association studies, especially for longitudinal family-based sequence data, has not been fully investi- ...family-based ...

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Genetic variation in inflammatory and bone turnover pathways and risk of osteolytic responses to prosthetic materials

Genetic variation in inflammatory and bone turnover pathways and risk of osteolytic responses to prosthetic materials

... We used knowledge of the haplotype architecture of candidate genes to conduct a screen for common variants across the whole of each gene, including its regulatory flanking sequences. We used a 2 stage design to reduce ...

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Development and characterization of microsatellite markers for Solen grandis using Illumina sequencing approach.

Development and characterization of microsatellite markers for Solen grandis using Illumina sequencing approach.

... related genetic analyses should be ...detecting genetic diversity, association mapping, genetic linkage mapping, and population and evolution analysis owing to their advantages such as hyper- ...

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Evolving temporal association rules with genetic algorithms

Evolving temporal association rules with genetic algorithms

... cyclic association rules are defined as rules that occur in user-defined intervals at regular periods throughout a ...mining association rules from partitions of the dataset and then pattern matching the ...

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Genetics and sychosis

Genetics and sychosis

... to genetic influences, in that monozygotic (MZ) twin pairs have considerably higher concordance (~45%) than dizygotic (DZ) twin pairs (~5-10%) (Cardno ...with genetic influences, in that biological ...

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