genetic-risk
Association between genetic risk scores and risk of narcolepsy: a case control study
... of genetic variations potentially underlying narcolepsy and prepared the grounds for building new risk prediction ...genomic risk estimates obtained from SNP genotyping into a genetic ...
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Lobular breast cancer: incidence and genetic and non genetic risk factors
... and genetic risk factors, and have shown that there were notable differences with ...use. Genetic risk factors vary depending on breast cancer histology, and CDH1 proves that genes involved in ...
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Is Ankyrin a genetic risk factor for psychiatric phenotypes?
... LA, Genetic Risk and Outcome in Psychosis (GROUP), Melle I, Djurovic S, Abramova L, Kaleda V, Sanjuan J, de Frutos R, Bramon E, Vassos E, Fraser G, Ettinger U, Picchioni M, Walker N, Toulopoulou T, Need AC, ...
5
Chromatin landscapes and genetic risk in systemic lupus
... of genetic risk for juvenile idiopathic arthritis (JIA) identified by genetic fine mapping using Illumina Immunochip arrays are enriched for H3K4me1 and or H3K27ac histone marks, epigenetic ...
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Variation in Both IL28B and KIR2DS3 Genes Influence Pegylated Interferon and Ribavirin Hepatitis C Treatment Outcome in HIV 1 Co Infection
... a genetic marker for a closely related tightly linked KIR gene that mediates the biological ...both risk loci, KIR2DS3 and IL28B-T, significantly increases the odds of failing to achieve SVR when compared ...
6
Evaluation of 64 candidate single nucleotide polymorphisms as risk factors for neural tube defects in a large Irish study population
... identify genetic risk factors for NTDs, we evaluated potentially functional single nucleotide polymorphisms (SNPs) that are biologically plausible risk factors for NTDs but that have never been ...
15
Breast cancer risk perception: what do we know and understand?
... of genetic risk counselling on risk accuracy has been shown repeatedly [10,12,14–16], and additional information in the form of a personal letter [10] or audiotape of the consultation [28], or a more ...
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The relationship between common genetic markers of breast cancer risk and chemotherapy induced toxicity : a case control study
... common genetic variants are confirmed to be associated with breast ...polygenic risk score was created from the 94 breast cancer risk variants, all of which were genotyped or successfully imputed in ...
14
Unlocking the treasure trove: From genes to schizophrenia biology
... The number of known genetic risk factors and evident genetic complexity speak to a need for high-throughput mutation screening to understand disease pathogenesis. So where, and how, do we begin to ...
5
Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci
... two-fold risk or greater for ...(average) risk to men in the 90–99% category of the PRS was ...average risk over the 90–99% category, so that the percentile of the PRS at which the risk ...
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The relationship between common genetic markers of breast cancer risk and chemotherapy-induced toxicity: A case-control study
... common genetic variants are confirmed to be associated with breast ...polygenic risk score was created from the 94 breast cancer risk variants, all of which were genotyped or successfully imputed in ...
13
Non genetic risk factors of long QT syndrome
... Environmental and genetic factors interact to define susceptibility to drug-induced long QT syndrome. Al- though erythromycin induces long QT syndrome, sub- stantial variability exists with regard to its ...
6
Combined effect of modifiable and non modifiable risk factors for colorectal cancer risk in a pooled analysis of 11 population based studies
... modifiable risk profiles can appre- ciably reduce the long- term absolute risks of developing ...modifiable risk scores can potentially be reduced to the average population risk through lifestyle ...
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Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium
... decreased risk of breast cancer (Johansson et al, 2007; Zhao et al, ...with genetic risk scores in the third tertiles are at increased risk of high grade PCA at 15% and of all PCA cases at 13% ...
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Common genetic effects on risk taking preferences and choices
... shown genetic correlations between several psychological characteristics and the tenden- cy to be an ...general risk preferences and the domain-specific risk preferences and the choice variables, ...
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Pre Weaning Morbidity and Mortality of Crossbred Calves in Bahir Dar Zuria and Gozamen Districts of Amhara Region, Northwest Ethiopia
... potential risk factors for mor- tality and morbidity and to determine the type and prevalence of major diseases of crossbred calves in Bahir Dar Zuria and Gozamen districts of Amhara ...(39.5%). Risk ...
8
Training genetic programming classifiers by vicinal-risk minimization
... Finally, implementation of VRM training used here is very simple and amounts to drawing an augmented training set, in advance, from the Parzen density estimate of the original data. For the case of small datasets where ...
24
The breast cancer susceptibility-related polymorphisms at the TOX3/LOC643714 locus associated with lung cancer risk in a Han Chinese population
... elevated risk of breast cancer and the other human diseases [16– ...increased risk of lung cancer in the ...cancer risk (Table 2), confirmed by logistic regression analyses in which lung cancer ...
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Original Article Association of six SNPs in SLC7A7 with glioma risk in a Chinese population
... intolerance [32]. A recent study carried out a study with 119 patients with pathologically confirmed glioblastoma, and reported that over expression of SLC7A7 is associated with poor outcomes in patients with ...
7
Cluster randomized controlled trial of a psycho educational intervention for people with a family history of depression for use in general practice
... of, risk-reducing strategies ’ ...of risk factors for development of depression and risk-reducing strategies, and perceived risk of developing depression or having a recurrence of family ...
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