genome maintenance
Features Distinguishing Epstein-Barr Virus Infections of Epithelial Cells and B Cells: Viral Genome Expression, Genome Maintenance, and Genome Amplification
... viral genome in their nucleus fired to express ...viral genome and expressing GFP and the EBERs made EBNA1, the genome maintenance protein, and less than 10% of cells made ...
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Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin induced nephropathy in mice
... Adriamycin (ADR) is a commonly used chemotherapeutic agent that also produces significant tissue damage. Mutations to mitochondrial DNA (mtDNA) and reductions in mtDNA copy number have been identified as contributors to ...
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Multiple Regulators of Ty1 Transposition in Saccharomyces cerevisiae Have Conserved Roles in Genome Maintenance
... the genome of Saccharomyces cerevisiae are transpositionally competent but rarely ...for genome maintenance suggests that Ty1 and yeast have coevolved to link transpositional dormancy to the ...
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The HU Protein Is Important for Apicoplast Genome Maintenance and Inheritance in Toxoplasma gondii
... own genome, a 35-kb DNA molecule that largely encodes proteins required for organellar transcription and ...apicoplast genome maintenance and function is a vali- dated target for drug therapy for ...
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Investigating the role of NSMCE2 in cell cycle progression and genome maintenance
... the transfer of SUMO from E2 onto the substrate. These SP-RING motif ligases can be further sub-divided into PIAS family proteins or ‘others’. The PIAS proteins, for example PIAS1, have a shared 400 amino acid sequence ...
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Mitochondrial Genome Maintenance: Roles for Nuclear Nonhomologous End-Joining Proteins in Saccharomyces cerevisiae
... Respiration loss in yeast, scored by decreases in colony-forming units on a nonfermentable carbon source, can result from multiple types of mtDNA instability, including point mutations, large-scale deletions or ...
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Delineating the Requirements for Spontaneous DNA Damage Resistance Pathways in Genome Maintenance and Viability in Saccharomyces cerevisiae
... Although the ready identification of TLS ⫺ /NER ⫺ / Spontaneous mutation rates of haploid DNA damage resistance mutants: Since dissection analysis revealed that REC ⫺ spore colonies indi[r] ...
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Maintenance of genome stability by Fanconi anemia proteins
... of genome maintenance involves the interaction of Ub-FANCD2 and Bloom helicase (BLM) and their co-localization to the nucleus when replication forks ...
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Transcriptome-wide analyses indicate mitochondrial responses to particulate air pollution exposure
... the mitochondrial apoptotic pathway is tightly regulated by several factors such as Bcl-2 family members, altered in women, and the PI3K/AKT (busulfan) pathway modulated in men [37, 38]. Moreover, the TCA cycle, ...
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Hmi1p and UvrD : two Superfamily I helicases and their respective roles in S. cerevisiae mtDNA maintenance and E. coli methyl-directed mismatch repair
... The partial complementation result is enigmatic and an analysis of what this may mean is needed in order to suggest possible roles. It is simplest to think of a partial complementation phenotype as evidence that the ...
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A Spread-Deficient Cytomegalovirus for Assessment of First-Target Cells in Vaccination
... differences in the abilities of EC and Hc to activate a CD8 ⫹ T-cell response. In contrast to EC, Hc, one of the most impor- tant first targets for MCMV during acute infection (61), in- duced only a poor CD8 ⫹ T-cell ...
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The SMC5/6 Complex Interacts with the Papillomavirus E2 Protein and Influences Maintenance of Viral Episomal DNA
... The papillomavirus E2 protein is an essential viral regulatory factor with important functions in viral transcription, viral DNA replication, and viral genome maintenance (9). These E2 functions appear to ...
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The E1 Protein of Human Papillomavirus Type 16 Is Dispensable for Maintenance Replication of the Viral Genome
... for maintenance replication of the viral ...for maintenance replication of the viral genome, we used the HDK-K4DT cells harboring the E1-defective HPV16 genomes es- tablished with exogenous E1 ...
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The role of duplications in the evolution of genomes highlights the need for evolutionary-based approaches in comparative genomics
... a genome-wide catalog of gene trees to determine precise orthology and paralogy relationships across these ...Whole genome duplication cir- cumvents these constraints and relaxes the dichotomy, resulting in ...
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Enhancing Capacity Utilization of Coal Fired Thermal Power Plant through Better Operation and Maintenance Practices
... Performance evaluation of major HT auxiliary equipment were carried out at Unit 1 of 250 MW coal fired thermal power plant of Dahanu Thermal Power Station (CPRI, 2010, Investigation into performance of Thermal Power ...
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Maintenance of Genome Integrity by Mi2 Homologs CHD-3 and LET-418 in Caenorhabditis elegans
... In C. elegans, the germ line is the only tissue to undergo apoptosis as a response to stress, making it an ideal system for the identification of genes involved in maintaining cellu- lar homeostasis and promoting genetic ...
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A Modernization Procedure for the Maintenance of Printing Machinery
... The similarities between the manufacturing processes, raw materials and products of printing machines result in similar defective, corrective and maintenance features, which should be considered during management ...
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Common Threads in Persistent Viral Infections
... long-term maintenance of the viral genome, modulation of viral gene expression, viral subversion of apoptotic pathways, and avoidance of clearance by the immune ...
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Maintenance of Mitochondrial Morphology Is Linked to Maintenance of the Mitochondrial Genome in Saccharomyces cerevisiae
... the maintenance reticulum, a comparatively high rate of mtDNA escape, of mitochondrial compartments and genome integrity and, in combination with yme1, are deficient for growth on nonfermentable carbon ...
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Epigenetic reprogramming in mouse pre implantation development and primordial germ cells
... demethylation. Genome- wide quantification of underlying histone modifications would also provide key information about how epigenetic reprogramming ...quantify genome- wide epigenetic modifications from ...
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