Genome sequencing
Genome sequencing and crop improvement
... generation sequencing technologies and these provide a valuable resource for the mining of molecular markers (Imelfort et ...plant genome sequencing are given in table ...in genome ...
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Medical implications of technical accuracy in genome sequencing
... whole genome and exome sequencing were absent from benchmark calls but fell within high-confidence regions; therefore, one could consider these variants false ...systematic sequencing errors; these ...
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Ultrasensitive single genome sequencing: accurate, targeted, next generation sequencing of HIV 1 RNA
... final sequencing data ...single-genome sequencing (SGS), which virtually eliminates PCR error, bias, and recombination but is constrained by the limited number of sequences that can be obtained ...
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A comparison of whole genome sequencing with exome sequencing for family based association studies
... whole genome sequencing, and Table 3 lists the top 10 SNPs from GWAS together with 3 exome-sequencing ...whole genome sequen- cing is chr3:106206487 (rs2590204, p = ...exome sequencing, ...
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Whole-genome sequencing in bacteriology: state of the art
... high-throughput sequencing. A number of sequencing techniques have been subsequently introduced making bacterial genome sequencing significantly cheaper and ...for sequencing of large ...
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Genome sequencing: a systematic review of health economic evidence
... the sequencing of the human genome has become a major biological and clinical research ...for genome sequencing, we conducted a thorough systematic review of the literature from 17 ...whole ...
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Whole-genome sequencing in an autism multiplex family
... ASDs are highly heritable and that the vast majority of the mutations identified are inherited mutations. We note that one rare exception was published recently, which demonstrated that some familial ASDs were asso- ...
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Whole-genome sequencing and the clinician: a tale of two cities
... whole-genome sequencing data con fi rmed that the causative COL6A3 variant was detected, but not inter- pretively fl agged, due to the inadequacy of our ( JH, NMP) pipeline (at the time) for predicting ...
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Quantifying the mapping precision of genome wide association studies using whole genome sequencing data
... whole-genome sequencing (WGS) data from 3642 unrelated individuals of European descent, we show that the association signals at rare causal variants (minor allele frequency ≤ ...
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A plant pathology perspective of fungal genome sequencing
... Clearly, genome sequencing projects have placed an affecting food security or commercial ...fungal genome sequencing may (at least partly) be attributed to food ...of genome ...
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On the Ethics of Clinical Whole Genome Sequencing of Children
... exome sequencing (WES) to diagnose a pediatric patient with a rare digestive ...whole genome sequencing (WGS) and has since re- ceived requests from around the world to perform ...of ...
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Statement on bioinformatics and capturing the benefits of genome sequencing for society
... Human Genome Organisation’s (HUGO) Committee on Ethics, Law and Society (CELS) under- took a Working Group exploration of the key ethical issues arising from genome sequencing, focusing on bio- ...
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Snake Genome Sequencing: Results and Future Prospects
... Snake genome sequencing is in its infancy—very much behind the progress made in sequencing the genomes of humans, model organisms and pathogens relevant to biomedical research, and agricultural ...
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Whole Genome Sequencing in Epidemiology of Campylobacter jejuni Infections
... of genome sequencing in surveillance would be expected to facilitate the identification of possible case clusters, which should allow for the implementation of more effective intervention strategies targeted ...
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Clinical use of whole genome sequencing for Mycobacterium tuberculosis
... Whole genome sequencing (WGS) has been shown to provide a rapid and comprehensive view of the genotype of the organism, and thus enable reliable prediction of the drug susceptibility phenotype within a ...
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The invasome of Salmonella Dublin as revealed by whole genome sequencing
... MM: conceived and designed the study, carried out data analyses and interpretation, conducted literature search and review, and wrote the first draft. SH, PL and RH: contributed to data interpretation, and critically ...
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Mutational analysis of non-coding genome in prostate cancer using whole genome sequencing
... “whole genome sequencing of large numbers of relapsing primary and metastatic PCas promises to define a genetic cartography that assists in tumor classification, elaborates mechanisms of carcinogenesis and ...
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Whole-genome sequencing of matched primary and metastatic hepatocellular carcinomas
... Notably, a frameshift insertion in WNT5A and an in- frame deletion in DAAM2 were detected only in lung metastases; both WNT5A and DAAM2 are involved in the Wnt signaling pathway. Recent genome sequencing ...
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Prediction of Staphylococcus aureus Antimicrobial Resistance by Whole Genome Sequencing
... Whole-genome sequencing (WGS) could potentially provide a single platform for extracting all the information required to pre- dict an organism’s phenotype. However, its ability to provide accurate ...
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Whole genome sequencing of nine esophageal adenocarcinoma cell lines
... Recent genome-wide sequencing projects have shown that EAC is one of the most highly mutated solid cancers with a high degree of heterogeneity (Dulak et ...whole genome sequencing and aligned ...
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