genome-wide association scan
Genome wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein kinase C gene
... Genome-wide association scan of neuropathic pain symptoms post-total joint replacement highlights a variant in the protein-kinase C PRKCA gene.. The genetics of neuropathic pain symptoms[r] ...
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A genome wide association scan on estrogen receptor negative breast cancer
... of a gene to the gene. To elucidate pathways with more biological relevance, we further conducted pathway ana- lysis based on a subset of SNPs with known regulatory functions. Recent studies have observed that whereas ...
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Genome wide association scan for chronic periodontitis implicates novel locus
... We selected 20 single nucleotide polymorphisms that had consistent results in both analyses of the total sample and self-reported Whites only to test in two independent co- horts (Table 2). Inclusion of sex, ethnicity, ...
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Genome-Wide Association Scan Identifies Candidate Polymorphisms Associated with Differential Response to Anti-TNF Treatment in Rheumatoid Arthritis
... Population admixture (that is, sam- pling of subjects from two or more sub- populations) has been recognized as a major cause for inconsistent results and spurious associations for genetic studies (19,20). U.S. ...
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A Genome Wide Association Scan of Bovine Tuberculosis Susceptibility in Holstein Friesian Dairy Cattle
... Genome wide analysis of the association between the TB EBV and each SNP was performed after correcting for the underlying population ...The genome wide Manhattan plot displaying the ...
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A genome wide association scan for rheumatoid arthritis data by Hotelling's T2tests
... First, we applied the Hotelling ’ s test statistics and performed a genome-wide scan on the NARAC data by analyzing one SNP at a time. The NARAC data contained a total of 2062 individuals (868 cases ...
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Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data.
... of association with osteoarthritis for the signals highlighted from the overlap analysis (tables 1 and 2) was carried out using 4324 stage 2 cases from the arcOGEN Consortium and 6518 population-based controls ...
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Genome-wide association Scan of dental caries in the permanent dentition
... We explored all signals with “suggestive significance” (P-value ≤ 10E-5) using several online bioinformatics tools and databases, such as SCAN (http://www.scandb. org/) [25], and WGAViewer ...
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A Twin Study of Breastfeeding With a Preliminary Genome-Wide Association Scan
... Breastfeeding has been an important survival trait during human history, though it has long been recog- nized that individuals differ in their exact breastfeeding behavior. Here our aims were, first, to explore to what ...
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A Genome-wide Pleiotropy Scan for Prostate Cancer Risk
... the association between rs16844874 and rs2216405 and circulating sarcosine concentrations in one of the BPC3 studies with available data (Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial, ...this ...
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GENOME-WIDE ASSOCIATION STUDIES IN PHARMACOGENOMICS
... Genome wide association studies (GWAS) are genetic studies in which dense array of genetic markers that capture substantial proportion of common variations in the genome sequence are typed in ...
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Genome wide scan reveals association of psoriasis.pdf
... the association of at least seven genetic loci and psoriasis (each with combined P o 5 10 8 ...confirmed association include HLA-C, three genes involved in IL-23 signaling (IL23A, IL23R, IL12B), two genes ...
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Genome wide linkage scan for loci influencing plasma triglyceride levels
... conduct genome-wide linkage scans to map loci that influence fasting triglyceride levels in plasma before and after fenofibrate was administered to GOLDN ...from genome-wide single-nucleotide ...
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Genome-Wide Scan for Adaptive Divergence and Association with Population-Specific Covariates
... indirect genome-scan approaches ultimately resides in the biological interpretation of the footprints of selection identi- fied, ...evaluate association of ecological variables with marker genetic ...
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A genome wide linkage and association scan reveals novel loci for autism
... for genome-wide significance, suggesting that there are not many common loci of moderate to large effect size even in a highly heritable disorder like ...with genome-wide significant evidence ...
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Genome wide gene based association study
... human genome, chromosomal regions on which to apply multilocus association tests should be defined in ...multilocus association test is performed in each ...then scan each chromosome ...
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Patient complexity and genotype-phenotype correlations in biliary atresia: a cross-sectional analysis
... the association of BA with these immunity disorders [29], the findings reminded us that immunity deregulation has been postulated to play a major role in BA pathogenesis [30], which notably, has been supported by ...
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Genome-wide linkage scan on estimated breeding values for a quantitative trait
... A genome-wide linkage scan was performed on Replicate 1 of the simulated data for fasting triglyceride ...A genome-wide linkage scan was run on both the new breeding value traits ...
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A Genome-Wide Scan of DNA Methylation Markers for Distinguishing Monozygotic Twins
... CpG island (CGI) methylation. According to the MeDIP score, among 27,841 CGIs, the range of partially methy- lated, completely methylated, and unmethylated regions of eight samples were 11,324–18,050, 4,189–5,474, and ...
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A Genome Wide Association Study for Longevity in Cattle
... The second selected SNP was at bp position 22,346,858 of chromosome 14. The fdr method selected 3 SNPs one more, and the q-value threshold a total of 4 SNPs in the region between bp positions 22,260,373 to 22,563,086 on ...
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