Genomics and Proteomics
The proBAM and proBed standard formats: enabling a seamless integration of genomics and proteomics data
... (HUPO) Proteomics Standards Initiative, we introduce here two novel standard data formats, proBAM and proBed, that have been developed to address the current challenges of integrating mass spectrometry-based ...
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Integrated Molecular Signature of Disease: Analysis of Influenza Virus-Infected Macaques through Functional Genomics and Proteomics
... vivo genomics experiments with influenza virus-infected macaques by focusing on the innate immune response at day 2 postinoculation and on gene expression in affected lung tissue with viral genetic material ...and ...
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Genomics and Proteomics of Mycobacteriophage Patience, an Accidental Tourist in the Mycobacterium Neighborhood
... Genomics and Proteomics of Mycobacteriophage Patience, an Accidental Tourist in the Mycobacterium Neighborhood Genomics and Proteomics of Mycobacteriophage Patience, an Accidental Tourist in the Mycob[.] ...
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Platelet genomics and proteomics in human health and disease
... Genomics and proteomics in hematological disease Transcript profiling is being used to investigate a number of platelet disorders, although no published studies have focused directly on [r] ...
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Genomics, microRNA, epigenetics, and proteomics for future diagnosis, treatment and monitoring response in upper GI cancers
... Recently, it has been suggested that in order to more accurately elucidate the origin of cancers, a detailed per- sonalized and individualized conceptual model is needed in terms of both strategy and content [20]. Both ...
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Integrated genomics and proteomics of the Torpedo californica electric organ: concordance with the mammalian neuromuscular junction
... shotgun proteomics of insoluble electric organ fractions in which mass spectral mapping was based on a preliminary library composed of 607 cDNA sequences ...
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Environmental genomics and proteomics of plant associated microbial dimethylsulfide degradation in a coastal salt marsh
... Figure 5.7 DGGE for bacterial 16S rRNA gene of 12C and 13C-labelled DNA fractions 3 to 12 recovered from ‘heavy’ and ‘light’ gradients of phyllosphere leaf washings of Spartina anglica p[r] ...
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Human genomic diversity, viral genomics and proteomics, as exemplified by human papillomaviruses and H5N1 influenza viruses
... This paper discusses specific examples illustrating the phenomenon of diversity of hosts and pathogens, with special reference to human papillomaviruses and H5N1 influenza viruses.. We a[r] ...
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The host range, genomics and proteomics of Escherichia coli O157:H7 bacteriophage rV5
... Based upon the proposed assignment to a genus being the presence of 40% conserved proteins [28,75], the five fully sequenced phages could be grouped in the “V5likevirus” genus. The submitting author is now of the opinion ...
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Functional genomics and proteomics of the cellular osmotic stress response in `non model' organisms
... To overcome current limitations for proteomics in non- model species and to increase the success rate of protein identification, a number of technical improvements can be made. In particular, efforts directed at ...
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Biomarkers for Bone Tumors: Discovery from Genomics and Proteomics Studies and Their Challenges
... were quite a number of studies per formed on Ewing sarcoma in relation to the search for biomarkers (Table 2). In 2012, Yu et al. (80) proposed circu lating cellfree mitochondrial DNA (ccf mtDNA) for application as ...
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Proteogenomics in Microbiology: Taking the Right Turn at the Junction of Genomics and Proteomics
... In any newly sequenced bacterial genome annotated through the computational methods of functional and comparative genomics, proteins with unknown functions account for 30–40% of all encoded proteins [75–77]. There ...
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Genomics and proteomics: Applications in autoimmune diseases
... In this review, we examine recent genomic and proteomic studies of clinical relevance, and provide examples of the following: (a) identification of new pathways and nove[r] ...
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Genomics and proteomics approaches to the study of cancer-stroma interactions
... FCR-L participated in the design of the study and analysis of the data, carried out cell culture, RaSH experiments and drafted the manuscript. PPJr helped with RaSH experiments. AV and GMP carried out proteomics ...
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Life Language Processing: Deep Learning-based Language-agnostic Processing of Proteomics, Genomics/Metagenomics, and Human Languages
... a genomics setting by proposing short k-mers as computationally inexpensive while being effective in the phenotype prediction in comparision with conventional gene presence/absence and SNPs ...
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Sarcoptes scabiei: genomics to proteomics to biology
... canis proteome is predicted to contain one chymotrypsin-like protein and at least 13 trypsin-like serine proteases and ten serine proteaselike proteins in addition to 18 serine protease-[r] ...
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The genomics of micronutrient requirements
... questionnaires (FFQ) are usually preferred over diet records or 24-h recalls because they are more suitable and accurate in assessing long-term or habitual exposure to specific nutrients (Mason 2003). However, repeated ...
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Proteomics: taking over where genomics leaves off
... called proteomics. The term proteomics was coined in 1995 by an Australian postdoctoral fellow Marc Wilkins as a complement of genomics, the study of genes (Wilkins et ...
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Proteomics of Toxoplasma gondii
... bioinformatics, proteomics has become established as an integral component in the post-genomics era by providing first-hand data on the functional products of gene ...
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Whither genomics?
... of genomics often called proteomics: the development and use of techniques to measure the post-trans- lational modification state, localization, binding partners, and ideally the catalytic activity of every ...
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