Germ Cell Tumors
The spermatogonial stem cell niche in testicular germ cell tumors
... of Cell Biology and Histology and 2 Analytical and High Resolution Biomedical Microscopy Core Facility, University of the Basque Country, Vizcaya, Spain ABSTRACT Spermatogonial stem cells (SSCs) are pluripotent ...
12
Hematopoietic Stem-Cell Transplantation in the Treatment of Germ-Cell Tumors
... for germ-cell tumors is generally dictated by stage, risk subgroup, and tumor ...testicular tumors may be treated with orchiectomy with or without retroperitoneal lymph node ...whose ...
13
Pathobiology of germ cell tumors applying the gossip test!
... This brings me to an important spin off from our need for fresh tumor tissue for karyotyping. It forced us to collect tumor tissue at the operation theatres, first in the three Northern provinces of the Netherlands, and ...
11
Testicular germ cell tumors: the changing role of the pathologist
... Testicular germ cell tumors (TGCTs) are a heterogeneous g r o u p o f n e o p l a s m s d e r i v e d f r o m n e o p l a s t i c transformation of germ cells in the testis, but with different ...
5
Nodal/Cripto signaling in fetal male germ cell development: implications for testicular germ cell tumors
... Testicular germ cell tumors (TGCT) encompass a broad group of cancers, each displaying different levels of pluripotency and differentiation as well as malignancy ...TGCT cell of origin is ...
10
Endocrine disruptors, gene deregulation and male germ cell tumors
... 1 Department of Cellular and Molecular Biology. Centro de Investigaciones Biológicas (CSIC), Madrid, Spain, 2 Hospital General Universitario Gregorio Marañón, Madrid, Spain and 3 Department of Biomedicine and Prevention, ...
16
Clinical Profile of Children with Extra Cranial Germ Cell Tumors
... differential diagnosis, newly appreciated, and controversial issues. Mod Pathol. 2005;18:S61–S79. 51. Schropp KP, Lobe TE, Rao B, Mutabagani K, Kay GA, Gilchrist BF, et al. Sacrococcygeal teratoma: The experience of four ...
101
High-Dose Chemotherapy and Stem-Cell Rescue for Metastatic Germ-Cell Tumors
... erm-cell tumors are curable even in the presence of metastatic ...metastatic germ-cell tumors can be classified into good-, intermediate-, and poor-risk disease, with corresponding cure ...
9
Subject: Hematopoietic Stem Cell Transplantation for Germ Cell Tumors 9/17/14
... Germ cell tumors are a type of tumor that begins in the cells that give rise to sperm or ...eggs. Germ cell tumors can occur almost anywhere in the body and can be either benign ...
10
Extragonadal Germ Cell Tumors in Children and Adolescents - a 20 Year Study
... Abstract Germ cell tumors (GCTs) are rare neoplasms which are seen in all age groups and both sexes. GCTs in the pediatric age group show considerable variation from their adult counterparts in ...
8
Original Article Clinical characteristics of malignant ovarian germ cell tumors
... Departments of 1 Gynecologic Oncology, 2 Obstetrics, Tianjin Central Hospital of Gynecology Obstetrics, Tianjin, China Received June 16, 2016; Accepted April 20, 2017; Epub July 15, 2017; Published July 30, 2017 ...
8
Genomic screening of testicular germ cell tumors from monozygotic twins
... Several genes have been described as associated with TGCT susceptibility including TERT, SPRY4, BAK1, DMRT1, ATF7IP and KITLG . In the present study, a genomic screening approach was performed for a pair of 26-year old ...
9
Malignant Mixed Germ Cell Tumors of the Ovary: A Series of Rare Cases
... mixed germ cell tumors of the ovary were encountered among 528 patients of ovarian tumors from Sep- tember 2009 to January 2018 in the department of Obstetrics and Gynecology, Guru Gobind ...
6
Pathogenesis of Testicular Germ Cell Tumors from a Developmental Point of View
... Chapter 6 Introduction The most abundant malignancies among male population between the ages of 17 and 45 years are germ cell tumors (GCTs; Adami et al. 1994). They comprise a heterogeneous group of ...
183
Quality of Life among Long Term Survivors of Ovarian Germ Cell Tumors.
... nondysgerminomatous tumors. The most common types of nondysgerminomatous tumors are yolk sac tumor, immature teratoma, and mixed germ cell tumors, with embryonal carcinoma, ...
64
Testicular germ cell tumors and related research from a historical point of view
... Testicular germ cell tumors and related research from a historical point of view IVAN DAMJANOV* ,1 and NICOLAI WEWER-ALBRECHTSEN 2 1 Department of Pathology and Laboratory Medicine, The University of ...
5
Differential expression of Mediator complex subunit MED15 in testicular germ cell tumors
... Abstract Background: Testicular germ cell tumors (TGCT) are the most common cancer entities in young men with increasing incidence observed in the last decades. For therapeutic management it is ...
6
Management of the primary malignant mediastinal germ cell tumors: experience with 54 patients
... Methods: A total of 54 patients with PMMGCT in a follow-up from 1990 to 2009. We evaluated the role of the surgical treatment and the effect of multimodality treatment strategy for patients with PMMGCT. Results: ...
6
Pretreatment Diagnosis of Suprasellar Papillary Craniopharyngioma and Germ Cell Tumors of Adult Patients
... with germ cell tumors who were older than 16 years of age were diagnosed at our ...mixed germ cell tumor; and 7 pa- tients with germinoma were diagnosed on the basis of clinical and ...
10
Primary Spinal Germ Cell Tumors: A Case Analysis and Review of Treatment Paradigms
... spinal germ cell tumors are exceedingly ...spinal germ cell tumors and a review of the ...intramedullary germ cell ...
7