germ layers
Nucleosome organizations in induced pluripotent stem cells reprogrammed from somatic cells belonging to three different germ layers
... three germ layer somatic cells; the similarity of the nu- cleosome organizations between these cells and normal ESCs was then ...three germ layers of the viable all-iPSC mice were selected for the ...
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Differentiation of human osteosarcoma 3AB OS stem like cells in derivatives of the three primary germ layers as a useful in vitro model to develop several purposes
... multiple layers which strongly acquired osteocyte-like features and potently stained for ALP and ARS and produced OSC and OPN; they pro- duced neutral lipid-laden adipocytes which strongly stained for lipid ...
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Differentiation of Human Embryonic Stem Cells into Embryoid Bodies Comprising the Three Embryonic Germ Layers
... Our findings demonstrate that hES cells readily differentiate to cystic EBs in a similar manner and time scale to those reported for mES cells. In ES cells derived from the primate rhesus mon- key, it was reported that ...
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Coco regulates dorsoventral specification of germ layers via inhibition of TGFβ signalling
... To identify specific Coco-regulated TGFβ ligands, CocoMO injections were coupled with injection of MOs targeting specific TGFβ ligands (ActivinMO or Xnr5/6MO + β-Gal tracer) in order to test whether we could inhibit this ...
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Ilyanassa Notch signaling implicated in dynamic signaling between all three germ layers
... Ilyanassa Notch signaling implicated in dynamic signaling between all three germ layers MAEY GHARBIAH1, AYAKI NAKAMOTO1, ADAM B JOHNSON2, J DAVID LAMBERT2 and LISA M NAGY1* 1Department of Molecular an[.] ...
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Development of separated germ layers of rodent embryos on ectopic sites: a reappraisal
... Int J U \ lIioI 35 177 189(1991) 177 Development of separated germ layers of rodent embryos on ectopic sites a reappraisal SOZICA LEVAK SVAJGER', VLADIMIR KNEZEVIC' and ANTON SVAJGER" 1/nstitute of Bi[.] ...
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Generation of the germ layers along the animal vegetal axis in Xenopus laevis
... A series of initial experiments by Nieuwkoop suggested that a signal released by vegetal pole cells induces the overlying pro- spective ectoderm to form mesoderm in the marginal zone, thus generating the three ...
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Antagonism between β catenin and Gata a sequentially segregates the germ layers of ascidian embryos
... Many animal embryos use nuclear β -catenin (n β -catenin) during the segregation of endomesoderm (or endoderm) from ectoderm. This mechanism is thus likely to be evolutionarily ancient. In the ascidian embryo, n β ...
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Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells
... karyotyping and/or e-Karyotyping, and teratomas shown to be abnormal by eSNP-karyotyping, did not exhibit ECL cells and robustly differentiated into derivatives of all three germ layers. A causative ...
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Early differentiation patterning of mouse embryonic stem cells in response to variations in alginate substrate stiffness
... definitive germ layers, and was then undetectable as germ layer formation and segregation is completed [26]. This may directly relate to the state of differentiation that the ESD3 cells were in at ...
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Phosphatidylserine receptor is required for the engulfment of dead apoptotic cells and for normal embryonic development in zebrafish
... three germ layers (ectoderm, mesoderm or endoderm) that participate in the development of somites, primordial pharyngea and neuromeres, and in primary organogenesis and tailbud formation (Kimmel et ...
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... It is an autosomal dominant inherited disorder characterized by multiple tumor-like growths called hamartomas arising from all germ layers and an increased risk of cancer of breast, thyr[r] ...
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Erlacher, Christian (2009): Genetic analysis of the FLRT family of proteins during early mouse embryonic development. Dissertation, LMU München: Fakultät für Biologie
... Figure 10 Expression of FLRT during early post implantation development (A’,D’,G’,J’) Schematic drawings showing various stages of embryonic development and indicating developmental hallmarks, such as AVE migration ...
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Opening a can of centipedes: new insights into mechanisms of body segmentation
... The evolution of body axis segmentation is the subject of an historical debate in which the search for homolo- gies has recently focused on the developmental mecha- nisms underlying segment formation in three taxa: ...
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Fish Stem Cell Cultures
... Derivation and initial characterization by using above criteria represent a first step in the derivation of new ES cells. Several independent experiments are required to investigate the pluripotency in vitro and in ...
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Stem cells research: a boon for science and society
... HES/ES cells are derived from an epiblast, the inner mass of a blastocyst, stage of roughly 100 cells which is totipotent in nature i.e. they can give rise to fully functional organisms as well as every cell type in the ...
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Why does Jack, and not Jill, break his crown? Sex disparity in brain tumors
... different germ layers such as lung cancer (endoderm and mesodermal origins) and melanoma (neuroectodermal origin), suggesting that it may involve differences in non-cell autonomous effects on cancer cell ...
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Origin and evolution of endoderm and mesoderm
... Endoderm and mesoderm can separate in various ways from ectoderm. The variability of the cellular processes raises the question, whether these so differently produced germ layers are really of the same ...
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Regulation of Both Cell State and Gene Expression with Nutrient Gradient as Conserved Mechanism Differentiating the Cell Fates for Embryonic Gastrulation: A Theory
... three germ layers of gastrula in ...three germ layers of gastrula, with the endoderm manifesting expression of gene classes in nutritious condition and giving rise to the epithelium of ...
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Three-Dimensional Stem Cell Bioprinting
... Figure 1: The most common stem cell types. Each one has their own unique pathway and includes several possible descriptions. A) Somatic Cells, also known as adult stem cells, do not differentiate into a different type of ...
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