Glomerular mesangial cell proliferation
Triptolide Suppresses Glomerular Mesangial Cell Proliferation in Diabetic Nephropathy Is Associated with Inhibition of PDK1/Akt/mTOR Pathway
... regulate cell proliferation, survival and ...during cell cycle progression from G0-G1 to S phase ...cells proliferation [35], autosomal dominant polycystic kidney disease [36] and insulin ...
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Infusion of platelet derived growth factor or basic fibroblast growth factor induces selective glomerular mesangial cell proliferation and matrix accumulation in rats
... of cell proliferation in all kidneys was limited to the ...proteinuria, glomerular leukocyte, or platelet influx developed in any ...group. Glomerular matrix expansion with increased ...
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Rat glomerular mesangial cells synthesize basic fibroblast growth factor Release, upregulated synthesis, and mitogenicity in mesangial proliferative glomerulonephritis
... and cell proliferation are frequent findings in various glomerular diseases in ...potent mesangial cell mitogen in ...rat mesangial cell (RMC) proliferation, we ...
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Glomerular changes and alterations of zonula occludens 1 in the kidneys of Plasmodium falciparum malaria patients
... included proliferation of glomeru- lar cells, protein deposition in the glomerular space, and decreased in the glomerular area, aside from the presence of parasitized red blood cells (PRBCs) inside ...
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The interaction of modified low density lipoproteins with glomerular mesangial cell and its potential influence on glomerulosclerosis
... Their proliferation also seems to be governed by similar ...muscle cell growth is inhibited by heparin in vitro and in vivo (Clowes and Kamowsky, ...inhibits proliferation o f cultured MCs (Striker ...
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Hypercholesterolemia promotes early renal dysfunction in apolipoprotein E-deficient mice
... inhibit mesangial cell proliferation and therefore extracellular matrix production ...age-dependent mesangial expansion and reduction in glomerular filtration rate, as observed in adult ...
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Original Article MicroRNA-124 represents a novel diagnostic marker in human lupus nephritis and plays an inhibitory effect on the growth and inflammation of renal mesangial cells by targeting TRAF6
... induce glomerular mesan- gial and renal tubular epithelial cells via secret- ing IL-1β, IL-6, and TNF-α ...errant proliferation and the apoptosis of mesan- gial cells are frequently observed in LN ...using ...
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Original Article Clinical manifestations, pathological findings, long-term follow-up and prognosis in pediatric patients with IgM nephropathy
... revealed glomerular- capsule adhesions, interstitial inflammatory cell infiltration, and interstitial ...mild proliferation of mesangial cells and the mesangial matrix) were more likely ...
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Original Article Downregulation of lncRNA NEAT1 inhibits mouse mesangial cell proliferation, fibrosis, and inflammation but promotes apoptosis in diabetic nephropathy
... motes glomerular fibrosis through upregulating expression of pro-fibrotic factor transforming growth factor β1 (TGFβ1) ...facilitates cell proliferation and fibrosis ...inhibits cell ...
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Mesangial cell apoptosis: the major mechanism for resolution of glomerular hypercellularity in experimental mesangial proliferative nephritis
... of mesangial apoptosis leading to phagocytosis by neighboring mesangial cells was obtained in self-limited mesangial proliferation induced in rats by ...in glomerular cell number ...
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Lovastatin inhibits proliferation of rat mesangial cells
... inhibit proliferation of several cell ...reduced mesangial cellularity and glomerular injury in experimental renal ...and proliferation in rat glomerular mesangial ...
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Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin dependent kinase antagonist
... by mesangial cell (MC) proliferation and matrix ...FCS-induced proliferation ( P , ...experimental mesangial proliferative glomerulo- nephritis (Thy1 model) were divided into two ...MC ...
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Evidence for a mouse mesangial cell derived factor that stimulates lymphocyte proliferation
... the glomerular mesangium are served by at least two populations of cells-- a cell bearing microfilaments that regulates blood flow, and a phagocytic cell bearing Ia determinants and Fc ...mouse ...
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Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis Alpha smooth muscle actin is a marker of mesangial cell proliferation
... Mesangial cell proliferation is common in glomerulonephritis but it is unclear if proliferation is associated with any in vivo alteration in ...whether mesangial of mesangial ...
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Overexpression of the serpin megsin induces progressive mesangial cell proliferation and expansion
... the glomerular disease observed in megsin transgenic mice still remains ...unknown. Mesangial ECM mass is constantly regulat- ed by its synthesis and degradation (9–13), the latter being determined by the ...
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Effects of Dangguibuxue decoction on rat glomerular mesangial cells cultured under high glucose conditions
... Cell proliferation was evaluated by MTT (3-[4,5-dimeth- ylthiazol-2-yl]-2, 5-diphenyltetrazolium bromide) assay as described elsewhere [18, ...Briefly, mesangial cells (4 × 10 4 ) were plated in ...
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Inhibition of mesangial cell proliferation by E2F decoy oligodeoxynucleotide in vitro and in vivo
... of mesangial proliferative GN in a rat anti-Thy ...the mesangial matrix (mesangiolysis; references 53, ...MC proliferation accompanied by the glomerular accumulation of various ECM components ...
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Transforming growth factor beta Murine glomerular receptors and responses of isolated glomerular cells
... resident glomerular cells and the accumulation of mesangial matrix are histologic abnormalities which are observed in the course of many progressive glomerular ...mouse glomerular endothelial, ...
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Original Article Mitofusin 2 expression in IgA1 induced rat glomerular mesangial cells and IgA nephrology animal model
... between glomerular mesangial cell (GMC) proliferation and the expression of Mitofusin 2 (Mfn2), then to further confirm the underlying signal pathway take part in regulating mesangial ...
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Case Report Skin amyloidosis and mesangial proliferation with focal segmental sclerosing glomerulonephritis: a case report
... T cell of the glomerulus may direct attack glomerulus inherent cell and CD4+T cell could aggravate glomerulus tissue damage with inflammatory factor ...T cell infiltration in the renal ...
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