Glucose lowering
Pharmacokinetic and pharmacodynamic modeling of oral mitiglinide on glucose lowering in healthy Chinese volunteers
... plasma glucose levels have been studied in several hypoglycemic drugs [23, ...inhaled glucose in healthy humans has not been published ...on glucose lowering after a single oral ...decreasing ...
8
Impact of Glucose-Lowering Medications on Cardiometabolic Risk in Type 2 Diabetes
... beyond glucose-lowering, except in confirming the absence of a class adverse effect on heart failure and assuring safety in the presence of renal ...
18
Original Article Structure-activity relationship of berberine derivatives for their glucose-lowering activities
... on glucose consumption was similar to that of BBR, although it had better glucose-lowering efficacy in diabetic animals due to improved pharmaco- kinetics ...
7
Avoiding hypoglycemia: a key to success for glucose-lowering therapy in type 2 diabetes
... Hypoglycemia is common not only in type 1 diabetes, but also in type 2 diabetes. It has negative consequences for both the daily life and well-being of the patient, for the glycemic control of diabetes, and for long-term ...
9
Once-Weekly Glucose-Lowering Therapy for Type 2 Diabetes
... Efficacy in Clinical Trials The clinical effectiveness and tolerability of exenatide QW were demonstrated in six randomized, active-controlled trials (n = 3,223) in which mean A1C reductions over ~ 6 months ranged from ...
6
Nationwide trends in glucose-lowering drug use, Denmark, 1999–2014
... By using Medstat, we were able to obtain complete sales data on glucose-lowering drugs in Denmark during a 16-year period. Limitations of our study include lack of information on whether drugs were ...
7
Compared with insulin glargine, insulin degludec narrows the day to day variability in the glucose lowering effect rather than lowering blood glucose levels
... the glucose-lowering effect of insulin [fluctuations of blood glucose levels (BG) seen during the same time period] that occur when insulin glargine (glargine) is replaced with insu- lin degludec ...
8
Neuronal GLP1R mediates liraglutide’s anorectic but not glucose lowering effect
... improves glucose tolerance and causes weight loss ...control glucose and body weight in type 2 diabetic patients ...improves glucose tolerance while inhibition increases food intake and worsens ...
9
Influence of Benazepril on Glucose Lowering Effect of Glipizide in Normal and Diabetic Rats
... The aim of the present work was to assess the influence of benazepril on the glipizide action in healthy and streptozotocin induced diabetic albino rats using single and repeated treatments of selected doses (3mg, 6mg ...
9
SGLT2i: beyond the glucose-lowering effect
... of glucose-lowering drug that, because of their unique action mechanism, do not depend on insulin or islet β-cells in vivo to exert pharma- cological ...blood glucose and glycosylated hemoglobin, but ...
10
FGF19 action in the brain induces insulin independent glucose lowering
... promote glucose lowering through insulin-independent mechanisms is novel in the sense that previous work in this area has focused largely on hypothalamic control of hepatic Si (32, ...of glucose ...
11
Influence of Lisinopril on Glucose Lowering Effect of Glipizide in Normal and Diabetic Rats
... the glucose lowering effect of ...blood glucose levels were established in normal healthy ...blood glucose levels were analyzed as mentioned ...
11
STUDIES ON GLUCOSE LOWERING EFFICACY OF THE ACACIA SUMA ROXB ROOT
... on glucose tolerance test in normal rats is shown in Table ...blood glucose level was increased rapidly from the fasting blood glucose value and after that subsequently decreased after 30 min of ...
5
Blood Glucose Lowering Effect and Safety of the Aqueous Leaf Extracts of Zanha africana
... peripheral glucose uptake and regulate the activity and/or expression of the rate- limiting enzymes involved in carbohydrate metabolism pathway by acting as insulin secretagogues or insulin mimetics [29] ...
9
Evaluation of the hypoglycaemic activity of Bauhinia monandra leaf in Alloxan diabetic rats and INS 1 insulin cells
... blood glucose level to reduce to a level similar to that of the normoglyceamic rats at 4hrs (Table ...blood glucose lowering effect (Table 2) and the diminishing blood glucose lowering ...
16
<p>A Recent Achievement In the Discovery and Development of Novel Targets for the Treatment of Type-2 Diabetes Mellitus</p>
... including glucose-lowering agents like which suppress hepatic glucose production and increase glucose uptake, insulin secretagogues, like sulphonylureas and meglitinides, which enhance insulin ...
15
Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production
... of glucose per day to the systemic ...of glucose (∼91 grams) excreted in the urine secondary to SGLT2 inhibition by dapagliflozin on day ...its glucose lowering ...plasma glucose ...
7
<p>Evaluation of in vitro and in vivo Anti-Diabetic, Anti-Hyperlipidemic and Anti-Oxidant Activity of Flower Crude Extract and Solvent Fractions of <em>Hagenia Abyssinica</em> (Rosaceae)</p>
... utilize glucose and it is seen as the “ gold standard ” in diagnosing diabetes ...on glucose tolerance test in normal mice is shown in Table ...of glucose administration, the peak of blood ...
17
Pharmacist led therapeutic carbohydrate restriction as a treatment strategy for type 2 diabetes: the Pharm TCR randomized controlled trial protocol
... for lowering blood glu- cose, promoting weight loss, and achieving T2D ...facilitate lowering of A1C while safely reducing the use of glucose-lowering medications in T2D, particularly in more ...
9
Thesis
... blood glucose levels of the mice. One factor that effected blood glucose levels was induced stress the mice ...blood glucose levels, which can be seen by the spikes in blood glucose within the ...
7