Glycogen phosphorylase
Anomeric spironucleosides of -D-glucopyranosyl uracil as potential inhibitors of glycogen phosphorylase
... of glycogen phosphorylase (GP) might prevent unwanted glycogenolysis under high glucose conditions and thus aim at the reduction of excessive glucose production by the ...
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Glycogen Phosphorylase in Acanthamoeba spp.: Determining the Role of the Enzyme during the Encystment Process Using RNA Interference
... that glycogen is the main source of free glucose for the synthesis of cellulose in Acanthamoeba, partly as glycogen levels fall during the encystment ...discoideum), glycogen phosphor- ylase has been ...
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Anomeric spironucleosides of -D-glucopyranosyl uracil as potential inhibitors of glycogen phosphorylase
... 6. Goyard, D.; Kónya, B.; Chajistamatiou, A.S.; Chrysina, E.D.; Leroy, J.; Balzarin, S.; Tournier, M.; Tousch, D.; Petit, P.; Duret, C.; et al. Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against ...
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Toxoplasma gondii Requires Glycogen Phosphorylase for Balancing Amylopectin Storage and for Efficient Production of Brain Cysts
... that glycogen synthase is more expressed in the tachyzoite and TgGP is less expressed in the bradyzoite stage (6), suggesting that tachyzoites have more potential for amylopectin accumulation if the regulatory ...
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Molecular mechanisms of McArdle's disease (muscle glycogen phosphorylase deficiency) RNA and DNA analysis
... for phosphorylase mRNA by Northern ...muscle phosphorylase mRNA could be detected, while in three other cases, normal length mRNA was present in lower ...the phosphorylase gene as compared with ...
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RECENT TARGET BASED DISCOVERY OF ANTI DIABETIC AGENTS
... 19 Chen.L.et al 69 has designed and synthesized a series of novel benzamide derivatives and their inhibitory activities against glycogen phosphorylase GP in the direction of glycogen syn[r] ...
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“Clinical Assessment of Cardiovascular Disorders by Cardiac Biomarkers” by Akansha Gupta, Prabhat Shukla, Vrish Dhwaj Ashwlayan, India.
... glycogenolysis which is composed of two identical subunits like BB and MM iso-enzymes which are found in the human heart; however, the BB isoenzyme is the most important myocardial enzyme. It is known that ...
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Regulation of glycogen synthase and phosphorylase activities by glucose and insulin in human skeletal muscle
... changed glycogen phosphorylase ...regulates glycogen synthesis by a mechanism that involves dephosphorylation of glycogen synthase but not ...low glycogen synthase activities found in ...
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Quantification of the glycogen cascade system: the ultrasensitive responses of liver glycogen synthase and muscle phosphorylase are due to distinctive regulatory designs
... of glycogen phosphorylase (GP) and glycogen synthase (GS), enzymes involved in glycogen degradation (glycogenolysis) and synthesis (glycogenesis) respectively ...and glycogen synthesis ...
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A study of antioxidant activity, enzymatic inhibition and in vitro toxicity of selected traditional sudanese plants with anti diabetic potential
... their glycogen phosphorylase inhibition, Brine shrimp lethality and antioxidant activity using (DPPH) radical scavenging activity and iron chelating ...
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Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans
... hepatic glycogen synthesis exclusively through activation of glycogen synthase flux (protocol II versus ...hepatic glycogen cycling. The glycogen phosphorylase rate was z 60% of the ...
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THE EFFECT OF SEROTONIN (5 HYDROXYTRYPTAMINE) ON GLYCOLYSIS IN THE PERFUSED VENTRICLE OF THE FRESHWATER BIVALVE ANODONTA CYGNEA: EVIDENCE FOR PHOSPHORYLATION/DEPHOSPHORYLATION CONTROL OF PHOSPHOFRUCTOKINASE
... Biethinger et al. 1991). In contrast, phosphorylation of PK, possibly by cyclic-GMP- dependent protein kinase, alters its kinetic properties towards a less active enzyme form (Plaxton and Storey, 1984, 1985; Michaelidis ...
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Glycolytic and Associated Enzymes of Rainbow Trout (Oncorhynchus Mykiss) Red Cells: In Vitro and In Vivo Studies
... Maximal activities of glycolytic and associated enzymes of rainbow trout red cells Enzyme Glycolytic enzymes Glycogen phosphorylase Phosphoglucomutase Hexokinase Phosph.oglucoisomerase P[r] ...
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A regulatory role for cortisol in muscle glycogen metabolism in rainbow trout Oncorhynchus mykiss Walbaum
... muscle glycogen resynthesis after a bout of exhaustive exercise in rainbow ...in glycogen phosphorylase a (Phos a) activity and rapid increase in glycogen synthase (GSase I) activity, compared ...
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Glycerol synthesis in the rainbow smelt Osmerus mordax
... that glycogen is a source of glycerol in rainbow ...in glycogen phosphorylase activity in muscle, and perhaps liver, in winter and (2) the rapid depletion of liver glycogen reserves during ...
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ANTIHYPERGLYCEMIC AND ANTIOXIDANT POTENTIALS OF SESBANIA GRANDIFLORA LEAVES STUDIED IN STZ INDUCED EXPERIMENTAL DIABETIC RATS
... down glycogen (glycogenolysis) and by de novo synthesis of glucose (gluconeogenesis) from non-carbohydrate precursors such as lactate, amino acids and ...glycerol. Glycogen is the primary intracellular ...
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The traditional Chinese formulae Ling gui zhu gan decoction alleviated non alcoholic fatty liver disease via inhibiting PPP1R3C mediated molecules
... Background: Ling-gui-zhu-gan decoction (LGZG), a classic traditional Chinese medicine formula, has been confirmed to be effective in improving steatosis in non-alcoholic fatty liver disease (NAFLD). However, the ...
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Involvement of cellular metabolism in age-related LTP modifications in rat hippocampal slices
... Our morphological studies showed that in aged rats the laminar structure of the hippocampal formation is severely distorted and beta-amyloid plaques were present (Figure 4). These profound morphological alterations raise ...
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Regulation of hepatic gluconeogenesis and glycogenolysis by catecholamines in rainbow trout during environmental hypoxia
... A Liver pyruvate kinase activity for series I at 0-2 and 5-0mmoll ' phosphoenolpyruvate PEP concentrations and the ratio of activities at 0-2/5-OPEP and B glycogen phosphorylase activity[r] ...
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Adrenergic regulation of glycogenolysis in rat liver after cholestasis Modulation of the balance between alpha 1 and beta 2 receptors
... The effects of extrahepatic cholestasis upon adrenergic regulation of glycogenolysis and upon the numbers of adrenoceptors in rat liver were studied using isolated hepatocytes and plasma membranes, respectively. A 60% ...
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