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Golgi apparatus

Association of the Cellular Coactivator HCF-1 with the Golgi Apparatus in Sensory Neurons

Association of the Cellular Coactivator HCF-1 with the Golgi Apparatus in Sensory Neurons

... At least one function of HCF-1 in this context involves coordinating removal of repressive chromatin marks with pro- moting activating marks on nucleosomes across the viral IE gene promoter-enhancer domains. A component ...

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The N-glycosylation processing potential of the mammalian Golgi apparatus

The N-glycosylation processing potential of the mammalian Golgi apparatus

... the Golgi apparatus. Glycans entered the in silico Golgi apparatus one at a time, hence our model does not account for substrate competition or the potential effects of protein load in the ...

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The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing

The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing

... For further confirmation of the requirement of OPTN for TBK1 activation, we used primary cells from mice in which both the UBD and ZF domains of OPTN had been deleted (OPTN 470T ) [27]. The truncated protein was produced ...

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Ultrastructural Pathology of Golgi Apparatus
of Nerve Cells in Human Brain Edema

Ultrastructural Pathology of Golgi Apparatus of Nerve Cells in Human Brain Edema

... that Golgi fragmentation is an early and probably irreversible lesion in neurodegeneration, caused by a variety of mechanisms that may “trigger” ...the Golgi apparatus, a process that involves the ...

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Protein transport and the reassembly of the Golgi apparatus during telophase in HeLa cells

Protein transport and the reassembly of the Golgi apparatus during telophase in HeLa cells

... the Golgi apparatus is a system that Wattenberg has reconstituted which demonstrated that glycoprotein and glycolipid transport through this organelle proceed with the same kinetics, suggesting that ...

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Vesicular Trafficking of Incoming Human Papillomavirus 16 to the Golgi Apparatus and Endoplasmic Reticulum Requires γ Secretase Activity

Vesicular Trafficking of Incoming Human Papillomavirus 16 to the Golgi Apparatus and Endoplasmic Reticulum Requires γ Secretase Activity

... and protein disulfide isomerase (PDI). As shown in Fig. 7a and b, there was relatively little staining in uninfected cells, but markedly increased ER staining was observed in infected cells 20 h after infection, when ...

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Mineral Fabrication and Golgi Apparatus Activity in the Mouse Calvarium

Mineral Fabrication and Golgi Apparatus Activity in the Mouse Calvarium

... the golgi apparatus (juxtanuclear ...while golgi body activity was demonstrated by transfection with a specific green fluorescent construct (GFP/mannosidase ...culture golgi body activity and ...

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The novel BTB-kelch protein, KBTBD8, is located in the Golgi apparatus and translocates to the spindle apparatus during mitosis

The novel BTB-kelch protein, KBTBD8, is located in the Golgi apparatus and translocates to the spindle apparatus during mitosis

... the Golgi apparatus is located at the periphery of the nucleus, close to the ...the Golgi needs to be segregated and distributed to the two daughter ...the Golgi complex become fragmented and ...

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Human Rhinovirus 16 Causes Golgi Apparatus Fragmentation without Blocking Protein Secretion

Human Rhinovirus 16 Causes Golgi Apparatus Fragmentation without Blocking Protein Secretion

... Transfected HRV16 nonstructural proteins 2B, 3A, and 3AB inhibit cellular secretion. As 2B induced ER aggregates and 3A and 3AB induced Golgi apparatus disruption, we evaluated if these events had any ...

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Impact on the Endoplasmic Reticulum and Golgi Apparatus of Turnip Mosaic Virus Infection

Impact on the Endoplasmic Reticulum and Golgi Apparatus of Turnip Mosaic Virus Infection

... and Golgi apparatus into that structure for the compartmentalization of viral gene products needed for virus ...Curiously, Golgi bodies were not found in the perinuclear com- partments for GFLV and ...

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NKG2D Ligand MICA Is Retained in the cis-Golgi Apparatus by Human Cytomegalovirus Protein UL142

NKG2D Ligand MICA Is Retained in the cis-Golgi Apparatus by Human Cytomegalovirus Protein UL142

... Human cytomegalovirus (HCMV) evades T-cell recognition by down-regulating expression of major histo- compatibility complex (MHC) class I and II molecules on the surfaces of infected cells. Contrary to the “missing-self ” ...

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Characterization of a Novel Golgi Apparatus-Localized Latency Determinant Encoded by Human Cytomegalovirus

Characterization of a Novel Golgi Apparatus-Localized Latency Determinant Encoded by Human Cytomegalovirus

... the Golgi apparatus ...the Golgi apparatus, as it did not colocalize with a marker for the endo- plasmic reticulum (protein disulfide isomerase [PDI]) or early endosomes (early endosomal ...

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Retention and targeting in the Golgi apparatus

Retention and targeting in the Golgi apparatus

... and Golgi (COPI) membranes using stage specific in vitro transport assays to synchronise movement of cargo to and from the IC, and GDP- and GTP-restricted forms of Sari and ARFl proteins to control coat ...

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Balanced trafficking between the ER and the Golgi apparatus increases protein secretion in yeast

Balanced trafficking between the ER and the Golgi apparatus increases protein secretion in yeast

... To increase the protein secretory capacity in a SEC16 overexpression strain by enlarging the retrograde traf- ficking pathway, two ARF GAPs mediating COPI vesi- cle formation, Gcs1p and Glo3p were overexpressed (Fig.  ...

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Morphological analysis of the Golgi apparatus in Schizosaccharomyces pombe

Morphological analysis of the Golgi apparatus in Schizosaccharomyces pombe

... the Golgi apparatus (reviewed in Warren, ...the Golgi apparatus was observed by immunofluorescence, as a disperse but punctate stain throughout the cell cytoplasm (Burke, et ...the ...

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Q&A: What is the Golgi apparatus, and why are we asking?

Q&A: What is the Golgi apparatus, and why are we asking?

... the Golgi (Figure 3a). Second, the Golgi adds post-translational modifications to the cargo proteins traveling through from the ...the Golgi has a major role in the biosynthesis of proteoglycans in ...

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Fierce Competition between Toxoplasma and Chlamydia for Host Cell Structures in Dually Infected Cells

Fierce Competition between Toxoplasma and Chlamydia for Host Cell Structures in Dually Infected Cells

... host Golgi apparatus using the following equation: [sum intensity (pathogenic vacuole center)/sum intensity (entire host Golgi apparatus)] ⫻ ...

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Illuminating the Sites of Enterovirus Replication in Living Cells by Using a Split-GFP-Tagged Viral Protein

Illuminating the Sites of Enterovirus Replication in Living Cells by Using a Split-GFP-Tagged Viral Protein

... In this study, we used a split-GFP system (34) to tag the 3A protein of CVB3, a small protein of 89 amino acids with a C-terminal hydrophobic domain that inserts into the RO membranes (35). This split-GFP system is based ...

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Membrane Phospholipid Asymmetry Counters the Adverse Effects of Sterol Overloading in the Golgi Membrane of Drosophila

Membrane Phospholipid Asymmetry Counters the Adverse Effects of Sterol Overloading in the Golgi Membrane of Drosophila

... the Golgi apparatus, for example, by VAP’s recruitment of OSBP to the ER (Ma et ...the Golgi apparatus, and when overexpressed or mutated, they can suppress defects caused by Osbp ...

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A novel mechanism for persistence of human cytomegalovirus in macrophages.

A novel mechanism for persistence of human cytomegalovirus in macrophages.

... a Golgi apparatus resident enzyme (28); and a polyclonal goat anti- human antibody to transferrin receptor which is also an early endosome marker ...

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