graft versus host
Pathogenesis of the graft-versus-host reaction in chick embryos
... 1 INTRODUCTION The development of the graft-versus-host concept 1 Evidence in favour of the graft-versus-host concept The nature of the effector cell 2 Genetic relation between host and [r] ...
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Pathophysiology, prevention, and treatment of acute graft-versus-host disease
... Over the last five decades, allogeneic hematopoietic stem cell transplant (HSCT) has become the treatment of choice for many hematologic malignancies, immunodefi- ciency disorders, hemoglobinopathies, genetic disorders, ...
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The immunogenetics of chronic graft versus host disease and its relevance for the graft versus leukemia effect.
... The debate whether (chronic) graft versus host disease (cGvHD) after bone marrow transplantation reduces the chance of leukemic relapse is certainly not definitively settled, but the maj[r] ...
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Original Article Effects of regulatory dendritic cells on graft-versus-host disease and graft-versus-leukemia in mice after allogeneic bone marrow transplantation
... acute graft-versus-host disease (GVHD) and graft-versus-leukemia (GVL) in leukemia mouse model after allogeneic bone marrow transplantation (al- ...
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Differential roles of IL 1 and TNF α on graft versus host disease and graft versus leukemia
... in graft-versus-host disease (GVHD) after experimental bone marrow trans- plant (BMT) when cyclophosphamide (Cy) is added to an otherwise well-tolerated dose (900 cGy) of total body irradiation ...in ...
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Cytokine mediators of chronic graft versus host disease
... Chronic graft-versus-host disease (cGVHD) is a multi- system inflammatory disease characterized by tissue fibrosis and mucosal lichenoid plaques that develop late after BMT and now represents the ...
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Nitric oxide production in host versus graft and graft versus host reactions in the rat
... or graft-versus-host disease, with the exception of the skin and sponge matrix graft models, where elevated serum NO2-/NO3- levels were never ...
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The MEK inhibitor trametinib separates murine graft-versus-host disease from graft-versus-tumor effects
... however, graft-versus-host disease (GVHD) limits its indication and success ...against host antigens ...and graft-versus-tumor (GVT) effects against residual host tumor ...
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Correlation of T-Cell Subsets and Hypercholesterolemia of the Donor and Its Association with Acute Graft-versus-Host Disease
... preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow ...the graft and the risk of acute graft-versus-host ...
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Bilateral corneal ulceration in ocular graft-versus-host disease
... Purpose: To report on corneal ulceration in ocular graft-versus-host disease (GVHD). Methods: This was a retrospective, observational case series investigating corneal ulceration and perforation in a ...
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HDAC Inhibition and Graft Versus Host Disease
... Histone deacetylase (HDAC) inhibitors are currently used clinically as anticancer drugs. Recent data have demonstrated that some of these drugs have potent antiinflammatory or immunomodulatory effects at noncytotoxic ...
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The paranasal sinuses of patients with acute graft versus host disease
... After engraftment allogeneic transplant, fever is not uncommon. Common causes include si- nusitis, pulmonary cytomegalovirus or aspergil- losis, hepatosplenic candidiasis, and venous catheter infections. Approximately ...
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Novel regulatory therapies for prevention of Graft-versus-host disease
... without graft rejection and ...inhibiting graft-versus-host reactions and selectively eliminating activated T cells in response to donor antigens in minor histocompatibility disparity [38] and ...
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Graft versus host disease and microchimerism in a JAK3 deficient patient
... Background: The lymphohematopoietic cells originating from feto-maternal trafficking during pregnancy may cause microchimerism and lead to materno-fetal graft versus host disease (GVHD) in severe ...
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Graft versus host disease can be separated from graft versus lymphoma effects by control of lymphocyte trafficking with FTY720
... recognizing host alloantigens is associ- ated with beneficial graft-versus-tumor effects in recipients of allogeneic hematopoietic cell trans- ...desired graft-versus-leukemia or ...
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HIF 1α inhibitor echinomycin reduces acute graft versus host disease and preserves graft versus leukemia effect
... Acute graft-versus-host disease (aGVHD) remains a major obstacle against favorable clinical outcomes following allogeneic hematopoietic stem cell transplantation ...weakening graft- ...
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The gut microbiota and graft versus host disease
... acute versus chronic GvHD ...of Graft-versus-host disease (GvHD) is a common complication of hematopoietic cell transplantation that negatively impacts ...
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Review Article Association of gut decontamination and graft versus host disease in allogeneic hematopoietic stem cell transplantation: a meta-analysis
... er C, Koestler J, Peter K, Zhu W, Sporrer D, Hehlgans T, Kreutz M, Holler B, Wolff D, Eding- er M, Andreesen R, Levine JE, Ferrara JL, Gess- ner A, Spang R and Oefner PJ. Metagenomic analysis of the stool microbiome in ...
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Graft versus Host Disease After Blood Transfusions in a Premature Infant
... Graft versus Host Disease After Blood Transfusions in a Premature Infant. Services[r] ...
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Mesenchymal stromal cells for the prophylaxis and treatment of graft-versus-host disease—a meta-analysis
... prevent graft rejection and reduce the tumor ...severe graft-versus-host disease and its effi- cacy is comparable with HLA-matched HSCT ...
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