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grey matter

Complement is activated in progressive multiple sclerosis cortical grey matter lesions

Complement is activated in progressive multiple sclerosis cortical grey matter lesions

... hippocampus grey matter (GM) were identified by histological and immunohistochemical assessment ...deep grey matter—thalamus), in comparison to non-neurological controls ...ing grey ...

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Meningeal and cortical grey matter pathology in multiple sclerosis

Meningeal and cortical grey matter pathology in multiple sclerosis

... white matter as subpial, rather than leukocortical demyelinated lesions ...white matter; and the fact that the center of the lesion is in the grey and not in the white matter [27] as most ...

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Dissociated grey matter changes with prolonged addiction and extended abstinence in cocaine users

Dissociated grey matter changes with prolonged addiction and extended abstinence in cocaine users

... as grey matter volume, may provide an indication of what might be different from the onset of abstinence in those who maintain ...gray matter volume in the parietal-occipital sulcus, medial and right ...

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Limbic grey matter changes in early Parkinson's disease

Limbic grey matter changes in early Parkinson's disease

... disease-related grey matter ...amygdala grey matter deficit, we consider the second interpretation as more like- ly despite absence of temporal cortical deterioration evi- dence from VBM in ...

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Grey matter volume alterations in CADASIL: a voxel-based morphometry study

Grey matter volume alterations in CADASIL: a voxel-based morphometry study

... Different volumetric approaches, mainly based on a priori hypotheses, have been used to assess the involve- ment of specific cortical regions in the disease and their relation to patients’ clinical status [8, 10, 11]. ...

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Clinical correlates of grey matter pathology in multiple sclerosis

Clinical correlates of grey matter pathology in multiple sclerosis

... white matter (WM) was driven by the higher sensitivity of the conventional MRI techni- ques to the WM changes ...to grey matter (GM) changes [23-28] have shown that the GM damage is more preva- lent ...

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Field strength dependence of grey matter R2* on venous oxygenation

Field strength dependence of grey matter R2* on venous oxygenation

... hard to interpret if the underlying function was not in fact linear. Future studies designed specifically to explore these relationships should use a multi-echo EPI readout and vascular crushing to separate the different ...

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Computational genetics analysis of grey matter density in Alzheimer’s disease

Computational genetics analysis of grey matter density in Alzheimer’s disease

... We first mapped each of the SNPs from the GWAS to individual genes using a window of 500 kb upstream and downstream from the gene sequence. This window size was se- lected to capture as many regulatory SNPs as possible ...

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Voxel based meta analysis of grey matter changes in Alzheimer’s disease

Voxel based meta analysis of grey matter changes in Alzheimer’s disease

... There are several methodological limitations of this study, some of which are inherent to all meta-analytical approaches. One limitation is the accuracy of the results, because peak-based meta-analyses are based on ...

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Multimodal MRI of grey matter, white matter, and functional connectivity in cognitively healthy mutation carriers at risk for frontotemporal dementia and Alzheimer's disease

Multimodal MRI of grey matter, white matter, and functional connectivity in cognitively healthy mutation carriers at risk for frontotemporal dementia and Alzheimer's disease

... connectivity. The resulting group-level ICA spatial maps were compared to previously described resting-state net- works [67–71], and we selected default mode network components and salience network components for dual ...

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Diffuse reduction of cerebral grey matter volumes in Erdheim-Chester disease

Diffuse reduction of cerebral grey matter volumes in Erdheim-Chester disease

... In this study we present group-level analysis of cortical thickness and subcortical volumes in 11 ECD patients compared to age-matched healthy controls. Despite the small number of patients, reduction of cortical ...

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A geometric network model of intrinsic grey matter connectivity of the human brain

A geometric network model of intrinsic grey matter connectivity of the human brain

... (white matter) connectivity and grey matter architecture to be included; however, to reemphasise, we concentrate here only on the dense and short-range connections that exist within the cortical ...

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Spread of pathology in amyotrophic lateral sclerosis: assessment of phosphorylated TDP-43 along axonal pathways

Spread of pathology in amyotrophic lateral sclerosis: assessment of phosphorylated TDP-43 along axonal pathways

... of grey matter and ten images of white matter were taken at 200x magnification (approximately 8 % of the aver- age motor strip) and the number of inclusions observed in neuronal cell bodies ...

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Quantification of neurodegeneration by measurement of brain-specific proteins

Quantification of neurodegeneration by measurement of brain-specific proteins

... The observation that GFAP levels were 3–fold higher in the spinal cords of mice with chronic EAE compared to control animals is in keeping with the observation that extensive gliosis is a pathological hallmark of the ...

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23   Lessons of ALS imaging: Pitfalls and future directions   A critical review

23 Lessons of ALS imaging: Pitfalls and future directions A critical review

... While meta-analyses could potentially presage the sort of infor- mation large multicentre studies can offer, surprisingly few meta- analyses have been carried out in ALS. An individual patient data (IPD) meta-analysis of ...

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Update on cerebral small vessel disease: a dynamic whole-brain disease

Update on cerebral small vessel disease: a dynamic whole-brain disease

... white matter and subcortical grey matter, including recent small subcortical infarct, lacunes, white matter hyperintensities (WMHs), prominent perivascular spaces (PVS), cerebral microbleeds ...

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Holographic Microwave Imaging Array for Brain Stroke Detection

Holographic Microwave Imaging Array for Brain Stroke Detection

... Figure 5 displays the 2D and 3D views of a 3D head model that contains skin, fat, skull, cerebral spin fluid (CSF), grey matter, white matter and an ischemic or hemorrhagic stroke area. The ...

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Boundary Extraction in Images Using Hierarchical Clustering based Segmentation

Boundary Extraction in Images Using Hierarchical Clustering based Segmentation

... viz. Grey matter, White matter and the stroke affected ...(white matter) and blue (Grey matter) it has misclassified some of the pixels not belonging to the diseased area as ...

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Expression of ecotropic murine leukemia virus in the brains of C58/M, DBA2/J, and in utero-infected CE/J mice.

Expression of ecotropic murine leukemia virus in the brains of C58/M, DBA2/J, and in utero-infected CE/J mice.

... infectious ecotropic MuLV clone AKR-623 (2). At 7 months of age, the mice of both litters were sacrificed and their brains were analyzed by Northern or in situ hybridization for eco- tropic MuLV RNA expression. ...

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Proteomic Analysis of Mouse Brain Subjected to Spaceflight

Proteomic Analysis of Mouse Brain Subjected to Spaceflight

... the grey matter, enolase 2 (ENO2) was upregulated after flight, also suggesting glycolysis may be ...the grey matter, SEC22B (SEC22 homolog B, vesicle trafficking protein), also complexes with ...

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